Clinical trials: Sleep Apnea Syndromes, Obstructive
Obstructive Sleep Apnea
Effects of Different Treatment Modalities for Obstructive Sleep Apnea on Temporomandibular Joint
this study aims to evaluate the subjective symptoms, clinical and radiographic signs of temporomandibular disorders related to the use of CPAP, MAD and physical therapy in the treatment of patients with obstructive sleep apnea.
- Trial name
- NCT05510882
- Testing
- different treatment modalities for OSA
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Obstructive Sleep Apnea
Titration of Oral Appliance Therapy: a Prospective, Randomized Cross-over Trial.
In this prospective randomized cross-over trial, 3 different titration procedures will be compared: 1. titration of the mandibular advancement device (MAD) in the home setting based on both the physical limits of the patient's…
- Trial name
- NCT03716648
- Testing
- DISE-assisted titration, PSG-guided titration, subjective titration
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- University Hospital, Antwerp
Obstructive Sleep Apnea of Child
Single Cell Sequencing of Tonsillar Tissue in Children With OSA
Obstructive sleep apnoea (OSA) in children is a prevalent sleep disorder, and is characterised by repetitive complete or partial upper airway obstruction during sleep.
- Trial name
- NCT05115968
- Testing
- Tonsillectomy
- Where
- Hong Kong
- Volunteers
- 16 people
- Sponsor
- Chinese University of Hong Kong
Airway Edema, Obstructive Sleep Apnea
Comparison of the Effect of Supine and Prone Position on the Ultrasonographic Airway Measurements
The aim of this study is to compare the preoperative and postoperative ultrasonographic measurements of patients undergoing in the prone position and the change in upper airway edema.
- Conditions
- Airway Edema, Obstructive Sleep Apnea, Respiratory Complication
- Trial name
- NCT05197400
- Testing
- preoperative airway ultrasonography, postoperative airway ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Sleep Apnea, Obstructive
Force Sensing Resistor for Obstructive Sleep Apnea Patients After Tongue Base Reduction Surgery
Obstructive sleep apnea syndrome (OSA) is a sleep-related breathing disorder defined by repetitive episodes of apnea and hypopnea.
- Trial name
- NCT05133011
- Testing
- Tongue base reduction surgery
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- National Cheng-Kung University Hospital
Moderate Obstructive Sleep Apnea Syndrome
Upper Airway Reeducation in Moderate Obstructive Sleep Apnea Syndrome
The aim of this study is to evaluate the effectiveness of a specific reeducation performed by speech therapists in moderate obstructive sleep apnea syndrome, as an alternative to the continuous Positive Anyway Pressure (CPAP) and…
- Trial name
- SAOSGENIO (NCT05911971)
- Testing
- Experimental
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obstructive Sleep Apnea
Comparison Between UPPP and Tonsillectomy in Adult OSA
The aim of this randomized control study is to evaluate the effect of tonsillectomy with or without uvulopalatoplasty in treating adults with moderate to severe sleep apnea.
- Trial name
- NCT02523248
- Testing
- tonsillectomy, Uvulopalatopharyngoplasty
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska University Hospital
Obesity Hypoventilation Syndrome (OHS)
Evaluation of Upper Extremity Functions in Obesity Hypoventilation Syndrome Patients
Obesity Hypoventilation Syndrome (OHS) is a disease characterized by daytime hypercapnia and sleep-related respiratory disturbances in individuals with a body mass index (BMI) greater than 30 kg/m², without any other condition…
- Trial name
- NCT06766110
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Istanbul University - Cerrahpasa
Obstructive Sleep Apnea Syndrome
Respiratory Muscle Training Combined With Aerobic Exercise in Obstructive Sleep Apnea Syndrome
In this study, which was planned to evaluate the effects of inspiratory and expiratory respiratory muscle training in addition to aerobic exercise in individuals with OSAS; 40 cases over the age of 40 who were diagnosed with…
- Trial name
- NCT05210998
- Testing
- Gradual Aerobic exercise training AND Respiratory muscle training, Gradual Aerobic exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul University - Cerrahpasa
Obstructive Sleep Apnea
Investigating a Wrist-sensor Oximeter to Screen for Sleep Apnoea.
The primary study objective is to investigate sensitivity and specificity of a wrist sensor pulse oximeter (the Oxitone Medical Oxitone 1000M device) to screen for obstructive sleep apnoea.
- Trial name
- NCT04018547
- Testing
- Patient wears a wrist sensor oximeter device for one to two nights.
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Oxitone Medical Ltd.
Apnea, Obstructive, Exercise Addiction
Development and Investigation of the ApneaTheraPlay
Obstructive Sleep Apnea Syndrome (OSAS) is commonly treated with CPAP devices, but adherence rates are low. Exercise has been shown to strengthen respiratory muscles, improve upper airway function, and enhance sleep quality.
- Conditions
- Apnea, Obstructive, Exercise Addiction, Physiotherapy and Rehabilitation
- Trial name
- NCT07214636
- Testing
- Structured Pre-Sleep Exercise, ApneaTheraPlay (ATP)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Medipol University
Sleep Apnea Syndromes
The POSAtive Study: Study for the Treatment of Positional Obstructive Sleep Apnea
This study is a prospective, multi-center, randomized crossover of the NightBalance SPT compared to APAP for the treatment of Positional Obstructive Sleep Apnea (POSA).
- Trial name
- NCT03061071
- Testing
- NightBalance Sleep Position Trainer (SPT), Automated Adjusting Positive Airway Pressure (APAP)
- Where
- 11 sites in United States
- Volunteers
- 117 people
- Sponsor
- NightBalance
Sleep Apnea, Obstructive
Group-based Peer Support Versus Individual Education for Patients Undergoing CPAP Treatment
The investigators will compare two alternatives designed to maximize adherence to continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA) - peer-support administered in groups, versus individual…
- Trial name
- NCT02538419
- Testing
- CPAP + Peer Support, CPAP + Individual Education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brigham and Women's Hospital
Sleep Apnea, Obstructive
Auto Continuous Positive Airway Pressure (CPAP) Based Energy Spectrum Analysis of Flow for Treatment of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Nasal Continuous Positive Airway Pressure (CPAP) is the standard therapy for obstructive sleep apnea hypopnea syndrome (OSAHS). This is most commonly administered as a single positive pressure that has been individualized for the…
- Trial name
- NCT00750165
- Testing
- SleepStyle 200 Auto Series CPAP Humidifier
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Fisher and Paykel Healthcare
OSA, Sleep Apnea
Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease?
Obstructive sleep apnea (OSA) is common in older adults and has recently been implicated in pathogenesis of Alzheimer's disease (AD). Research has shown that sleep disruptions have caused memory impairment.
- Conditions
- OSA, Sleep Apnea, Obstructive Sleep Apnea, Alzheimer Disease
- Trial name
- NCT05094271
- Testing
- Supplemental Oxygen, Continuous Positive Airway Pressure Machine, Room Air
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- University of California, San Diego
Obstructive Sleep Apnea, Hypertension
Effects of Antihypertensive Drugs in Patients With Hypertension and Obstructive Sleep Apnea (OSA)
The aim of the present study is to compare the effects of different types of antihypertensive drugs (angiotensin II receptor blockers and long-acting calcium channel blockers) in patients with hypertension and obstructive sleep…
- Trial name
- NCT01028534
- Testing
- Olmesartan and Azelnidipine
- Where
- 2 sites in Japan
- Volunteers
- 150 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Obstructive Sleep Apnea, Refractory Hypertension
Effects of Continuous Positive Airway Pressure (CPAP) in Patients With Resistant Hypertension and Obstructive Sleep Apnea (OSA)
Obstructive sleep apnea (OSA) is an important cause of refractory hypertension but the impact of treatment with continuous positive airway pressure (CPAP) is not completely understood.
- Trial name
- NCT00812695
- Testing
- CPAP
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Obstructive Sleep Apnea, Depressive Symptoms
Quality of Life in Patients With Obstructive Sleep Apnea: The Role of CPAP Associated to Psychological Support
Many researches have shown that patients with Obstructive Sleep Apnea (OSA) and often also the family members have a decreased quality of life, problems related to the sexual sphere, depressive disorders and anxiety problems.
- Trial name
- QUOLOSA (NCT02375321)
- Testing
- CPAP and Psychological support
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- Careggi Hospital
Obstructive Sleep Apnea (OSA)
Evaluate the Efficacy and Safety of GZR18 Injection in Obese Subjects With Obstructive Sleep Apnea Not Treated With Positive Airway Pressure (PAP) Therapy
This study is a multicenter, randomized, double-blind, parallel, placebo-controlled Phase III clinical trial evaluating the efficacy and safety of GZR18 injection in obese subjects with moderate to severe obstructive sleep apnea…
- Trial name
- NCT07493057
- Testing
- GZR18 injection
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Gan & Lee Pharmaceuticals.
Sleep Apnoea, Obesity & Overweight
Tirzepatide Versus Positive Airway Pressure for the Treatment of Obstructive Sleep Apnoea
When used, continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnea (OSA), a condition that is mainly caused by overweight and obesity.
- Conditions
- Sleep Apnoea, Obesity & Overweight, Sleep Apnea Syndrome, Obstructive
- Trial name
- TIRZE-PAP (NCT07846865)
- Testing
- Continuous Positive Airway Pressure, Tirzepatide
- Where
- Australia
- Volunteers
- 256 people
- Sponsor
- Woolcock Institute of Medical Research