Clinical trials: Sleep Apnea Syndromes, Obstructive
Obstructive Sleep Apnea Syndrome
Cytokine Profiles in Children With Obstructive Sleep Apnea
The purpose of this study is to compare the cytokine profile of tonsillar and peripheral blood mononuclear cells in patients with obstructive sleep apnea (OSA) and to compare the blood mononuclear cell cytokine secretion profile…
- Trial name
- NCT00456573
- Testing
- tonsillectomy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Sleep Apnea Syndromes, Sleep Apnea, Obstructive
How Does the Clinical and Paraclinical Efficacy of an Oral Appliance Evolved According to Propulsion: Control With Each mm of Advancement
The OAMMM study is a mono-centrer , non interventional, prospective study, carried out in CH Valence Oral Appliance is indicated for first line moderate sleep Apnea Syndrome or severe sleep Apnea Syndrome after failure of…
- Conditions
- Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Respiratory Tract Diseases
- Trial name
- OAMMM (NCT05056766)
- Testing
- questionnaires: Epworth Sleepiness Scale; Pichot fatigue questionnaire.
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier de Valence
Nocturia, Obstructive Sleep Apnoea
Clinical Trial of Desmopressin on Nocturia in Obstructive Sleep Apnoea Patients
The purpose of the study is to evaluate the efficacy of desmopressin on symptoms of nocturia in patients with Obstructive Sleep Apnoea (OSA). The improvement of sleep quality and the quality of life will be measured.
- Trial name
- NCT01530451
- Testing
- Desmopressin
- Where
- Hong Kong
- Volunteers
- 9 people
- Sponsor
- Chinese University of Hong Kong
Hypertension, Obstructive Sleep Apnea
Effect of Antihypertensive Agents Over Sleep Apnea
Obstructive sleep apnea and hypertension are well-known cardiovascular risk factors. Their control could reduce the burden of heart disease across populations.
- Trial name
- NCT01896661
- Testing
- Diuretics, Calcium Channel Blockers
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Sleep Apnea, Obstructive, Stroke
Sleep Apnea: Mechanism and Cerebrovascular Consequences
This study will determine the effect of ventilatory stimulation on obstructive sleep apnea in selected patients with stroke. We will select a subset of patients with stroke in the prior 3 months who are most likely to have…
- Trial name
- NCT00108602
- Testing
- acetazolamide
- Sponsor
- US Department of Veterans Affairs
Obstructive Sleep Apnea, Snoring
Childhood Adenotonsillectomy Study for Children With OSAS
The purpose of this research is to determine the effect of adenotonsillectomy surgery (removal of tonsils and adenoids) on obstructive sleep apnea syndrome (OSAS) in children.
- Trial name
- CHAT (NCT00560859)
- Testing
- Adenotonsillectomy (AT) - removal of adenoids and tonsils, Watchful Waiting
- Where
- 6 sites in United States
- Volunteers
- 453 people
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea
Obstructive Sleep Apnea Non-PAP Outcomes and Viable Alternatives
OSANOVA is a non-randomized clinical trial which aims to compare outcomes of mandibular advancement device (MAD) and hypoglossal nerve stimulation (HGNS) therapies in moderate-to-severe OSA patients who fail, decline, or are…
- Trial name
- OSANOVA (NCT07074288)
- Testing
- MAD, HGNS
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine
Snoring, Obstructive Sleep Apnea
Intraoral Tongue Stimulation for Treatment of Primary Snoring
Intraoral Neuromuscular Training for Treatment of Snoring Objective Studies show that improving pharyngeal muscle tone can ameliorate obstructive sleep apnoea (OSA) and snoring.
- Trial name
- NCT03829956
- Testing
- Intraoral tongue stimulator (Snoozeal)
- Where
- United Kingdom
- Volunteers
- 115 people
- Sponsor
- Signifier Medical Technologies
Obstructive Sleep Apnea
Promoting the Use of CPAP Therapy Among OSA Patients
Obstructive sleep apnea (OSA) is the most common sleep breathing disorder in the U.S. Continuous Positive Airway Pressure (CPAP) therapy is the most effective treatment for OSA.
- Trial name
- NCT04372329
- Testing
- CPAP4HealthySleep system
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Sarah Alismail
Sleep Apnea, Obesity
Upper Airway of Women With Obstructive Sleep Apnea After Bariatric Surgery
Evaluation of upper airway with Magnetic Resonance and polysomnographic at the pre and post operative of 23 women having undergone bariatric surgery (with the Y-Roux technique) for treatment of obesity.
- Trial name
- NCT05669469
- Testing
- Bariatric surgery
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Michel Burihan Cahali
Obstructive Sleep Apnoea, Primary Open-angle Glaucoma
PAIR Study-PAP And IOP Relationship: Study 2
Some people with Primary Open-angle Glaucoma (POAG) also suffer from Obstructive Sleep Apnoea (OSA), a common sleep disorder which is known to affect heart and blood vessels, and may contribute to glaucoma progression.
- Trial name
- PAIR2 (NCT03145129)
- Testing
- Continuous Positive Airway Pressure
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Obesity, Obstructive Sleep Apnea
Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy
This Phase 3 clinical trial is designed to evaluate the efficacy and safety of maridebart cafraglutide compared to placebo over a 52-week period in adults with obstructive sleep apnea (OSA) who are receiving positive airway…
- Trial name
- MARITIME-OSA-1 (NCT07225686)
- Testing
- Maridebart cafraglutide
- Where
- 61 sites in United States, Australia and 9 more
- Volunteers
- 250 people
- Sponsor
- Amgen
Obstructive Sleep Apnea
Questionnaires to Identify Chinese Patients at Risk for Obstructive Sleep Apnea
The purpose of this study is to validate the Berlin questionnaire and STOP-BANG (snore, tired, obstruction, pressure, body mass index (BMI), age, neck, gender) as effective screening tools for Chinese subjects who are suspected…
- Trial name
- NCT01171196
- Where
- Hong Kong
- Volunteers
- 378 people
- Sponsor
- The University of Hong Kong
Obstructive Sleep Apnea
Effectiveness of NOA OATMAD
This study is looking at how well the OrthoApnea NOA appliance, a special custom-made mouthpiece, helps treat people with obstructive sleep apnea (OSA).
- Trial name
- NCT07111962
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Alberta
Obstructive Sleep Apnea
Lifestyle Intervention Treatment for Patients With Mild Obstructive Sleep Apnea
The main objective of the study is to determine whether a supervised lifestyle intervention including individualized dietary counseling could be a curative treatment for patients with mild OSA.
- Trial name
- NCT00486746
- Testing
- Lifestyle intervention (physical activity and dietary counseling), General information on healthy lifestyle habits
- Where
- Finland
- Volunteers
- 81 people
- Sponsor
- Kuopio University Hospital
Sleep Apnea, Sleep Apnea, Obstructive
Predictive Accuracy of MATRx Plus in Identifying Favorable Candidates for Oral Appliance Therapy
Obstructive sleep apnea (OSA) is a common disease that is largely un-diagnosed and untreated. Standard treatment for obstructive sleep apnea, nasal continuous positive airway pressure (CPAP), entails use of a nose mask to deliver…
- Conditions
- Sleep Apnea, Sleep Apnea, Obstructive, Sleep Disordered Breathing
- Trial name
- NCT03217383
- Testing
- MATRx plus
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Zephyr Sleep Technologies
Obstructive Sleep Apnea (OSA), Ischemic Optic Neuropathy/Optic Nerve Stroke
Optic Nerve Injury in Obstructive Sleep Apnea Patients
Ischemic optic neuropathy (ION) is damage to the optic nerve caused by ischemia and hypoxia of the optic nerve due to an impairment of the blood supply to the optic nerve from the arteries.
- Trial name
- NCT06748703
- Testing
- CPAP Treatment
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Nanjing Medical University
Obstructive Sleep Apnea, Acute Myocardial Infarction
Prospective Observational Registry for Obstructive Sleep Apnea in Patients With Acute Myocardial Infarction
Obstructive sleep apnea (OSA) has been known as a risk factor for coronary artery disease, heart failure, cerebrovascular accident and atrial fibrillation.
- Trial name
- OSAAMI (NCT03600246)
- Testing
- WATCH-PAT
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Wonju Severance Christian Hospital
Obstructive Sleep Apnea-hypopnea in Multiple Sclerosis Patients
Sleep Apnea in Multiple Sclerosis Positive Airway Pressure Trial
Fatigue is highly prevalent among multiple sclerosis (MS) patients and has pervasive adverse effects on daily functioning and quality of life.
- Trial name
- SAMSPAP (NCT01746342)
- Testing
- Effective continuous positive airway pressure (CPAP)
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- McGill University
Obstructive Sleep Apnea
DISE: Phenotyping Obstruction Patterns
Drug-induced sleep endoscopy (DISE) represents an opportunity to evaluate the upper airway in sleep-like conditions. In its current clinical form, however, DISE does not routinely determine the functional impact of anatomic and…
- Trial name
- DISE-PhOP (NCT05050383)
- Testing
- Pharyngeal Manometry
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- University of Pennsylvania
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