Clinical trials: Sleep Apnea Syndromes, Obstructive
Sleep Apnea, Chronic Kidney Diseases
Impact of Obstructive Sleep Apnea (OSA) Treatment on Blood Pressure Control in Chronic Kidney Disease
The role of obstructive sleep apnea (OSA) on chronic kidney disease (CKD) is not clear. This randomized clinical trial will test the impact of OSA treatment on blood pressure (BP) and on the estimated glomerular filtration rate…
- Trial name
- NCT05846490
- Testing
- CPAP, Usual care
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- University of Sao Paulo
Heart Failure, Sleep Apnea, Obstructive
Adaptive Servo-Ventilation In Acute Heart Failure Patients Protecting the Heart and Kidneys
The primary hypothesis of this study is: the use of minute ventilation-adaptive servo-ventilation (MV-ASV) during hospitalization will mitigate deterioration in renal function and prevent kidney injury in patients admitted with…
- Trial name
- ASLEEP PK (NCT02796638)
- Testing
- Adaptive Servo-Ventilation
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Veterans Medical Research Foundation
Influenza
Tissue-specific Responses to Influenza Immunization and Their Relation to Blood Biomarkers (SLVP032)
The investigators collected blood and lymphoid tissues routinely discarded during surgery from adults after a routine seasonal influenza vaccination to determine how immune memory develops at the actual site of infection, and how…
- Trial name
- NCT03023709
- Testing
- Fluzone®, FluMist®
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Stanford University
Adenoid Hypertrophy
Conventional Curettage Versus Endoscopic Microdebrider-Assisted Adenoidectomy in Children
The purpose of this randomized clinical trial is to compare two surgical methods for removing enlarged adenoids in children: conventional curettage adenoidectomy and endoscopic microdebrider-assisted adenoidectomy.
- Trial name
- NCT07856771
- Testing
- Conventional Curretage Adenoidectomy, Endoscopic Microdebrider-Assisted Adenoidectomy
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Allama Iqbal Teaching Hospital
Obstructive Sleep Apnea
A Comparison of Surgical Outcome Following Drug-induced Sleep Endoscopic Diagnosis Using Propofol or Dexmedetomidine for Sedation : A Prospective Randomized Trial
Obstructive sleep apnea is a common disease, associated with cardiovascular disease, cerebrovascular disease, and many other medical conditions. Therefore the precise diagnosis and treatment are important.
- Trial name
- NCT01895348
- Testing
- Propofol, propofol-remifentanil, Dexmedetomidine-remifentanil
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Obstructive Sleep Apnea, Fluid Retention
MOdification of Fluid Distribution in 90 Minutes
Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) is a cardiovascular risk factor due to intermittent hypoxia phenomena. Several etiological factors are involved in the pathogenesis of OSAS.
- Trial name
- NCT05786248
- Testing
- Impedancemetry
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Poitiers University Hospital
Chronic Rhinosinusitis (Diagnosis), Nasal Polyps
NO Measurements in Screening for Asthma and OSA, in Patients With CRSwNP
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a condition resulting in varying degrees of nasal congestion, nasal secretion, facial pain and reduced or absent sense of smell.
- Conditions
- Chronic Rhinosinusitis (Diagnosis), Nasal Polyps, Asthma, Obstructive Sleep Apnea
- Trial name
- NCT03963648
- Testing
- Fractioned Exhaled Nitrogen Oxide measurements
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Christian von Buchwald
Sleep Apnea, Obstructive, Metabolism
Treatment of Sleep Apnea to Improve Metabolic Health
Diabetes and prediabetes prevail among obstructive sleep apnea (OSA) patients. OSA and short sleep both detrimentally affect glycemic control regardless of obesity.
- Conditions
- Sleep Apnea, Obstructive, Metabolism, CPAP, Patients Above 18 Years
- Trial name
- GLYCOSACT (NCT06848647)
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Uppsala University
Obstructive Sleep Apnea
Validation of Sleep Apnea Screening Device Phase II
Obstructive sleep apnea (OSA) is the most common type of sleep apnea. The marketplace currently does not have an affordable, easy-to-use, over-the-counter, home-based OSA screening device.
- Trial name
- NCT03025464
- Testing
- Obstructive Sleep Apnea Screening Device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Sleep Apnea, Heart Failure
Diagnosis and Treatment of Sleep Apnea in the Acute Exacerbation of Heart Failure
Congestive heart failure affects 2.3 percent of the population (approximately 4,900,000) with an incidence of 10 per 1,000 of the population after the age of 65 (1).
- Trial name
- NCT00701038
- Testing
- auto adjusting bi-level positive airway pressure device
- Volunteers
- 54 people
- Sponsor
- Rami Khayat
Obstructive Sleep Apnea
Usability Evaluation of Menai CPAP Masks
The primary objective of this study is to evaluate the subjective performance of the Menai mask systems (full face, nasal, and pillows variants), compared against Comparison mask systems.
- Trial name
- NCT02364375
- Testing
- Menai mask (full face), Menai Standard mask (full face), Menai mask (nasal)
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- ResMed
Obstructive Sleep Apnea
RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA
The goal of this randomised, double-blind phase II/III clinical trial is to determine the safety and efficacy of IHL-42X in subjects with obstructive sleep apnoea who are intolerant, non-compliant, or naïve to positive airway…
- Trial name
- REPOSA (NCT06146101)
- Testing
- IHL-42X Low Dose, IHL-42X High Dose, IHL-42X (Optimal Dose)
- Where
- 20 sites in United States
- Volunteers
- 121 people
- Sponsor
- Incannex Healthcare Ltd
Pediatric Obstructive Sleep Apnea
Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea
Background: Obstructive sleep apnea (OSA) occurs when the blockage of the airway causes a person to stop breathing involuntarily for 10 seconds or more throughout the night during sleep.
- Trial name
- NCT05052216
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Obstructive Sleep Apnea, Arrhythmia
Evaluation of Sleep Apnea and Cardiac Rhythm Abnormalities After Surgery Under General Anesthesia
Higher risk of cardiac and respiratory post-operative events is observed in patients with unrecognised Obstructive Sleep Apnea (OSA).
- Trial name
- Etude3A (NCT02833662)
- Testing
- Measure of ODI and heart rhythm
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Sleep Apnea
Effects of Suvorexant in Participants With Obstructive Sleep Apnea (MK-4305-036)
This study will evaluate the safety, tolerability, and effect of multiple doses of suvorexant (MK-4305) on respiratory function in participants with mild to moderate obstructive sleep apnea (OSA) compared to administration of…
- Trial name
- NCT01300455
- Testing
- Suvorexant
- Volunteers
- 26 people
- Sponsor
- Merck Sharp & Dohme LLC
Obstructive Sleep Apnea
REV 002 Observational Study of the ReVENT Sleep Apnea System: Minimally Invasive Treatment for Obstructive Sleep Apnea
The purpose of this post-market observational study is to assess the effectiveness and patient perception of benefit of the ReVENT Sleep Apnea System in patients diagnosed with Obstructive Sleep Apnea due to primary tongue base…
- Trial name
- NCT02180815
- Testing
- ReVENT Sleep Apnea System
- Where
- 14 sites in Belgium, Czechia and 3 more
- Volunteers
- 50 people
- Sponsor
- Revent Medical International B.V.
Obstructive Sleep Apnea
Comparative Efficacy Study of Titratable Versus Active Mandibular Advancement Splint in Sleep Apnea
Sleep apnea is a common disorder that occurs in 3-10 % of the adult population. This disorder disrupts the architecture and quality of sleep.
- Trial name
- SOMNYX (NCT02112435)
- Testing
- Somnyx ®, Narval ORM ® or SomnoDent ®
- Where
- 3 sites in Canada, France
- Volunteers
- 100 people
- Sponsor
- Université de Montréal
Obstructive Sleep Apnea
Evaluation of Sleep Apnea Related Inflammation With CRP, ESR and Neutrophil toLymphocyte Ratio
There is some evidence suggesting that OSA is associated with low level of systemic inflammation and oxidative stress. Low level systemic inflammation and subsequent vascular damage has been implicated as the underlying mechanism…
- Trial name
- NCT02272608
- Testing
- Evaluation of Sleep Apnea Related Inflammation with CRP, ESR and Neutrophil toLymphocyte Ratio
- Volunteers
- 279 people
- Sponsor
- Ordu University
Obstructive Sleep Apnea, CPAP
The Outcome of CPAP Titration Under Sleep Endoscopy
The outcome of CPAP titration under sleep endoscopy: A randomized controlled crossover trial
- Conditions
- Obstructive Sleep Apnea, CPAP, DISE
- Trial name
- NCT03523013
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Obstructive Sleep Apnea
Pilairo Lab Market Research
The purpose of the study is to observe the Pilairo mask in a lab setting.
- Trial name
- NCT01824979
- Testing
- CPAP mask ( Pilairo), Other CPAP mask
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Fisher and Paykel Healthcare
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.