Clinical trials: Sleep Architecture
Sleep, Sleep Deprivation
Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators
This study aims to investigate the effect of a 15-minute meditation practice on sleep architecture and high-frequency Heart Rate Variability (HF-HRV), as well as cognitive performance after both a well-rested and sleep-deprived…
- Conditions
- Sleep, Sleep Deprivation, Cognitive Change
- Trial name
- REST (NCT05026541)
- Testing
- Nap Practitioners, Shoonya Meditation
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Postpartum Women
Sleep Architecture as a Digital Biomarker for Postpartum Depression in Hong Kong Mothers
The goal of this study is to develop a postpartum depression (PND) Risk index using the UK Biobank dataset, and to validate the risk index in Hong Kong postpartum women.
- Trial name
- SLEEP-PD-HK (NCT07600593)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cold-water Immersion, High Heat Sauna
Thermodynamic Exposure and Sleep in Military Cadets
This pilot study investigates the effects of cold-water immersion, traditional sauna use, and their combination on sleep architecture and psychological health in military cadets.
- Conditions
- Cold-water Immersion, High Heat Sauna, Combination of Cold-water Immersion and High Heat Sauna
- Trial name
- NCT07201935
- Testing
- Cold Water Immersion, High Heat Sauna
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
HIV
Sleep and Cognition After Atripla to Stribild Switch
Atripla and Stribild are two FDA-Approved one pill a day combination antiretroviral medications given for the treatment of HIV. Both drugs are reasonably well tolerated.
- Trial name
- NCT02283060
- Testing
- Stribild, Atripla
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
MDMA Discontinuation Syndrome
Study of the Effects of MDMA/Ecstasy on Water Regulation, Sleep, and Cognition.
The purpose of this study is to measure the effects of MDMA on sleep, mood, thinking, and how your body retains water. The researchers are interested in the effects that occur a few hours after taking MDMA as well as effects…
- Trial name
- 2C (NCT01053403)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- California Pacific Medical Center Research Institute
Short Sleepers, Normal Sleepers
Homeostatic Regulation of Sleep in Short Sleepers
This single-center study targets adults with distinct sleep profiles, divided into three categories: natural short sleepers, characterized by a reduced nocturnal sleep duration; subjects with idiopathic hypersomnia (IH) followed…
- Conditions
- Short Sleepers, Normal Sleepers, Idiopathic Hypersomnia Patients
- Trial name
- HOMEOSHORT (NCT07584538)
- Testing
- Actigraphy, Polysomnographie (PSG 128), TILE test
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Tourette's Syndrome, Attention Deficit Hyperactivity Disorder
Study of Clonidine on Sleep Architecture in Children With Tourette's Syndrome (TS) and Comorbid ADHD
In the present study, we examine the question "Will day-time aggression in children improve when their night-time sleep is treated with pharmacological intervention (i.e.
- Trial name
- NCT00152750
- Testing
- APO-clonidine
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Sleep, Emotion
The Effects of Acute vs. Chronic of Screen Illumination on: Sleep Efficacy and Architecture, Physiology, Emotion and Behavior: Possible Effect on Human Health
The human eye has a dual role, which is reflected by the various photo-receptors used for vision of images and colors ,Image forming photoreceptors (IFP) and for entrainment of our "Biological clock" located in the hypothalamus…
- Trial name
- NCT02839395
- Testing
- No intervention- base line, Acute, Chronic
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Assuta Medical Center
Healthy, Sleep Quality
Study to Investigate Effects of a Herbal Drug Compared to Placebo on Sleep
To demonstrate the influence of a herbal preparation containing hypericum, passionflower, and valerian on sleep structure, improvement of attention, and well-being in comparison to placebo.
- Trial name
- sleep-EEG (NCT00997256)
- Testing
- Neurapas® balance (Herbal product (Hypericum, Passionflower, Valerian)), film-coated sugar-pill
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Parkinson Disease
Exercise and Sleep in Parkinson's Disease
This study will investigate the impact of two common exercise modalities, cardiovascular and resistance training, on sleep quality and architecture in persons with Parkinson's disease (PD), and whether these potential positive…
- Trial name
- NCT04558879
- Testing
- CT, RT
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McGill University
Sleep Architecture
Microgreens on Sleep
This study aims to investigate the effects of Microgreen use on sleep architecture in athletes. Sleep architecture refers to the structural organization of sleep, including the distribution of non-rapid eye movement (NREM) and…
- Trial name
- GREENSLEEP (NCT07537140)
- Testing
- cabbage for control, microgreen coctail was given orally
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Apnea, Sleep
Effects of CPAP on Cognitive Function, Neurocognitive Architecture and Function in Patients With OSA: The SMOSAT Trial
Multiple clinical studies have indicated that obstructive sleep apnea (OSA), the most common chronic sleep disorder, may affect neurocognitive function, and that treatment for continuous positive airway pressure (CPAP) has some…
- Trial name
- NCT02886156
- Testing
- CPAP, BSC
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Major Depressive Disorder
Effects of Seroquel XR on Sleep Architecture in Patients With Major Depressive Disorder
In this study, patients with major depressive disorder (MDD) who have insomnia symptom are treated with Seroquel XR in an open-label manner for a 4-week period with repeated measurements of insomnia symptoms and sleep parameters…
- Trial name
- NCT01189318
- Testing
- Quetiapine Fumarate Extended Release
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ewha Womans University
Sleep
Evening Screen Content and Sleep Architecture in Older Adults: Crossover RCT
Title The Effect of Evening Technology Use with Calming vs. Exciting Content on Sleep Architecture in Older Adults: A Crossover Randomized Controlled Trial Background The study explores how evening use of digital devices with…
- Trial name
- NCT07001514
- Testing
- Calming digital content, Exciting Digital Content, Non-digital book reading
- Where
- Sweden
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Sleep Bruxism, Adult
Sleep Architecture and Factors Associated With Definitive Diagnosis of Sleep Bruxism
This case-control study will evaluates the association between the definitive sleep bruxism diagnosis by gold-standard polysomnography examination obtained at Pelotas Sleep Institute and the sociodemographic, occupational…
- Trial name
- NCT03825237
- Testing
- Polysomnography
- Where
- Brazil
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Bruxism, Sleep-Related
Smartwatch Analysis of Sleep Bruxism
This study aims to investigate the differences in sleep stages and total sleep duration between individuals diagnosed with sleep bruxism and healthy controls.
- Trial name
- NCT07453121
- Testing
- Smartwatch-based Sleep Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Cappadocia University
Brain Age
Brain Age and Sleep Architecture in Meditators
This is a single-center, cross-sectional study that will recruit approximately fifty seven (57) meditators and fifty one (51) controls.
- Trial name
- BRANCH (NCT05513846)
- Testing
- DREEM EEG Device, SleepImage Ring
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Sleep Architecture, Cognitive Function
The Impact of Glycemic Index on Sleep and Memory Consolidation
The study will test whether the consumption of a low versus a high glycemic index pre-bed drink influences sleep architecture, memory consolidation, nocturnal glucose metabolism, and mood.
- Conditions
- Sleep Architecture, Cognitive Function, Mood, Glucose Metabolism
- Trial name
- NCT05591573
- Testing
- Low glycemic index drink, High glycemic index drink
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swansea University
Hypoxia, Sleep
Autonomic Activity During Nap Under Hypoxia
Sleeping under hypoxic conditions can impair cognition and autonomic nervous activity. A short daytime nap can modify these changes.
- Conditions
- Hypoxia, Sleep, Healthy
- Trial name
- NAPOXIA (NCT04146857)
- Testing
- Normoxia, Hypoxia 1, Hypoxia 2
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Sleep Architecture, Sleep Disorders
Sleep, Cognition and Memory Disorder
The increasing incidence of Alzheimer's disease (AD) and related sleep-disorders with the aging of the population is a major issue of public health. The prevalence of sleep disturbances is about 50% in dementia patients.
- Conditions
- Sleep Architecture, Sleep Disorders, Cognitive Impairment
- Trial name
- SCOAL (NCT01650454)
- Testing
- 2 night polysomnography, battery of neuropsychological tests, virtual reality test
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux