Clinical trials: Sleep Disordered Breathing
Spinal Cord Injuries, Sleep Disordered Breathing
Role of Mirtazapine in Ameliorating Sleep Disordered Breathing
The purpose of this study is to look at the effect of using Mirtazapine to target a specific pathway in the body, that relies on a natural chemical the body produces called 'serotonin', in patients with spinal cord injury (SCI)…
- Trial name
- NCT04799782
- Testing
- Mirtazapine
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Anemia, Sickle Cell, Sleep-Disordered Breathing
SMILES: Study of Montelukast in Sickle Cell Disease
Sickle cell disease (SCD) is a genetic blood condition causing long term health problems including pain and brain problems which affect quality of life.
- Trial name
- SMILES (NCT04351698)
- Testing
- Montelukast
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Sleep Disordered Breathing (SDB)
Comprehensive Care of Sleep Disordered Breathing
The Comprehensive Care of Sleep Disordered Breathing study (Care-SDB) is a prospective, multi-center, registry-based cohort study designed to investigate the integrated management of sleep-disordered breathing (SDB).
- Trial name
- Care-SDB (NCT07339371)
- Testing
- Clinical Management for SDB
- Where
- China
- Volunteers
- 11,100 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Adenotonsillar Hypertrophy, Obstructive Sleep Apnea
Ketorolac on Postoperative Pain Reduction in Pediatric Patients with Adenotonsillectomy
Postoperative pain management in the pediatric patient undergoing tonsillectomy is challenging. Despite being used in many procedures for postoperative pain management, perioperative ketorolac usage in pediatric tonsillectomy…
- Conditions
- Adenotonsillar Hypertrophy, Obstructive Sleep Apnea, Sleep-Disordered Breathing, Acute Post Operative Pain
- Trial name
- NCT05074056
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Preeclampsia, Gestational Diabetes
The Association Between High Risk Pregnancy and Sleep-disordered Breathing
The aim of the present study is to establish, using polysomnographic criteria and prospective nature, whether sleep apnea in pregnancy is more prevalent in women with high risk pregnancies including preeclampsia, gestational…
- Conditions
- Preeclampsia, Gestational Diabetes, Premature Labor
- Trial name
- NCT01022619
- Where
- 2 sites in Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
High Altitude, Healthy Adult
Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Healthy Individuals H
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in healthy individuals, who live permanently >2600m.
- Conditions
- High Altitude, Healthy Adult, Echocardiography, Pulmonary Resistance
- Trial name
- NCT07804485
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Pain, Postoperative, Tonsillar Hypertrophy
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis, Pediatric Sleep Apnea
- Trial name
- OPTIMAL (NCT06576830)
- Testing
- Methadone, Fentanyl/Hydromorphone
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Duke University
Sleep-disordered Breathing (SDB), Sleep Apnea
Validation of the Smart Mask V1 System and Its Measurements of SpO2 and Pulse Rate
The goal of this clinical study is to investigate a new medical device, the Smart Mask V1 System (herein 'Smart Mask'), and particularly its measurements of blood oxygen levels (SpO2) and pulse rate (PR) in healthy adults aged 18…
- Conditions
- Sleep-disordered Breathing (SDB), Sleep Apnea, Sleep Quality
- Trial name
- SMV1: PPG (NCT07086742)
- Testing
- Smart Mask V1 System
- Where
- Belgium
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Pathway Medtech, LLC.
Pregnancy Related, Sleep
Sleep in Late Pregnancy - Artificial Intelligence Development for the Detection of Disturbances and Disorders
SLeeP AID4 is a single-group, single-arm, Canada-wide, non-randomised, unblinded, in-home, observational study to prospectively collect and build a data set of natural sleep behaviour and physiology in maternal-fetal dyads (and…
- Conditions
- Pregnancy Related, Sleep, Sleep-Disordered Breathing, Sleep Disturbance
- Trial name
- SLeeP AID4 (NCT05376475)
- Testing
- Infrared video-audio camera, Level III home sleep apnea test, Maternal-fetal transabdominal electrocardiographic heart rate monitor
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shiphrah Biomedical Inc.
Obesity & Overweight Sleep, Obstructive Sleep Disordered Breathing
Ultrasound Assessment of Tongue Characteristics in Adolescents With Obesity and Obstructive Sleep Disorders
Obstructive sleep-disordered breathing, including obstructive sleep apnea (OSA), represents a significant yet underdiagnosed condition in the pediatric population, particularly among adolescents with obesity.
- Conditions
- Obesity & Overweight Sleep, Obstructive Sleep Disordered Breathing, Pediatric Obesity
- Trial name
- NCT07613944
- Testing
- Submental ultrasound
- Where
- 2 sites in Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Sleep Apnea Syndromes
Parent-QoL and Sleep Disordered Breathing
In this prospective case-control study the investigators will enrolled parents of 45 children younger than five years of age who were planned to undergo adenotonsillectomy due to an obstructive airway indication in an academic…
- Trial name
- NCT04501848
- Testing
- adenotonsillectomy
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Sleep Apnea, Obstructive
Evaluating the Relationship Between Sleep-Disordered Breathing and Daytime Alertness
Obstructive sleep apnea (OSA) is a serious sleep disorder in which a person repeatedly stops breathing, or experiences shallow breathing for short periods of time during sleep.
- Trial name
- NCT00393913
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Obstructive Sleep Apnea
A Research Study for Children About Heart Changes and Obstructive Sleep Apnea (OSA)
In this research study the investigators want to learn more about the risk of developing blood vessel and heart disease from night-time sleep apnea.
- Trial name
- NCT01837459
- Where
- United States
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Sleep-disordered Breathing, Sleep Apnea, Obstructive
Behavioral Effects of Obstructive Sleep Apnea in Children
Sleep-disordered breathing (SDB) in children may be responsible for disruptive daytime behaviors such as inattention and hyperactivity. Many children undergo tonsillectomy for SDB and disruptive daytime behaviors.
- Conditions
- Sleep-disordered Breathing, Sleep Apnea, Obstructive, ADHD
- Trial name
- NCT00060723
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Sleep Disordered Breathing, Upper Airway Collapsibility
Incidence of Sleep-disordered Breathing and Upper Airway Collapsibility in Postpartum Patients and Its Intervention
The investigators hypothesized that sleeping in a 45 degrees elevated body position decreases the likelihood of upper airway vulnerability to collapse early after delivery.
- Conditions
- Sleep Disordered Breathing, Upper Airway Collapsibility, Upper Airway Obstruction
- Trial name
- NCT01719224
- Testing
- elevated body position, supine body position
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital