Clinical trials: Sleep Disordered-breathing
Preeclampsia, Hypertension
CPAP in Preeclampsia
Study design: Single blinded randomised control trial Planned sample size: 30 (women randomized 2:1 to receive either CPAP or no CPAP) Objectives: Primary objective: Assess the effects of nasal CPAP on sleep physiology, 24 blood…
- Trial name
- NCT02303834
- Testing
- Continuous Positive Airway Pressure Ventilation (CPAP)
- Where
- 2 sites in Australia
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Sydney
HIV Infections, Sleep
Sleep Quality and Presence of Sleep Disordered Breathing
The purpose of our study is to survey the quality of sleep and sleep disordered breathing in a HIV infected inner city ambulatory African-American Population aged 50 years and older.
- Trial name
- NCT00692965
- Volunteers
- 74 people
- Sponsor
- University of Florida
Sleep-Disordered Breathing, Pulmonary Disease, Chronic Obstructive
Effect of Positive Airway Pressure Therapy on Hospitalization and Mortality in SDB Patients With Comorbid Chronic Obstructive Pulmonary Disease (COPD) or/and Heart Failure (HF)
The aim of the study is to test the hypothesis that treatment of sleep disordered breathing (SDB) in patients with comorbid chronic obstructive pulmonary disease (COPD) and/or heart failure (HF) with positive airway pressure…
- Conditions
- Sleep-Disordered Breathing, Pulmonary Disease, Chronic Obstructive, Heart Failure
- Trial name
- NCT02923505
- Testing
- polygraphy or polysomnography
- Where
- 5 sites in Denmark, France and 1 more
- Volunteers
- 383 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Schizophrenia and Schizophrenia Spectrum Psychosis
Investigation of Using Non-Wearable Devices to Assess Sleep- Disordered Breathing in Hospitalized Patients With Schizophrenia
This research project aims to evaluate the prevalence of comorbid OSA and its impact on disease progression among hospitalized schizophrenia patients using non-wearable devices.
- Trial name
- IUNWD (NCT07192042)
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Blood Pressure, Sleep-Disordered Breathing
High Blood Pressure in Paediatric Patients With Sleep Disorder Breathing.
There are data supporting a possible increase in the prevalence of High Blood Pressure (HBP) in pediatric patients with Sleep Disorder Breathing (SDB).
- Trial name
- NCT03696654
- Testing
- adenotonsillar surgery
- Where
- Spain
- Volunteers
- 286 people
- Sponsor
- Fundacion del Hospital Nacional de Paraplejicos para la Investigacion y la Integracion
Type 2 Diabetes, Obstructive Sleep Apnea
Sleep Disordered Breathing and Diabetes
The hypothesis of this study is: sleep disordered breathing (SDB), specifically, obstructive sleep apnea, is associated with poorer glucose in the existing type 2 diabetic condition.
- Trial name
- NCT00901472
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Chicago
Obstructive Sleep Apnea, Hypercapnia
Home-Based Diagnosis and Management of Sleep-Related Breathing Disorders in Spinal Cord Injury
Patients with spinal cord injury (SCI) usually breathe without any mechanical assistance, but significant breathing problems occur often during sleep, either because the upper airway closes (obstructive sleep apnea; OSA), or…
- Conditions
- Obstructive Sleep Apnea, Hypercapnia, Spinal Cord Injury
- Trial name
- NCT01882257
- Testing
- BiPAP, BiPAP/AVAPS (Phillips Respironics)
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- University of Michigan
Sleep Disordered Breathing, Obstructive Sleep Apnea
The Evaluation of an Alternative Sizing Model in Comparison of a Conventional Sizing Model for Full Face Masks in the Treatment of OSA in Terms of Performance and Comfort
The investigation is a prospective non-blinded and semi-randomized clinical investigation. The investigation is designed to assess the alternative sizing model which the trial mask concept is based on and how it compares to a…
- Trial name
- NCT02851628
- Testing
- Alternative sizing model based trial mask, Prototype Full Face Mask
- Where
- 4 sites in New Zealand
- Volunteers
- 20 people
- Sponsor
- Fisher and Paykel Healthcare
Lung Transplantation, Sleep-disordered Breathing
Sleep-disordered Breathing After Solid Organ Transplantation
Sleep-disordered breathing (SDB) describes a group of disorders in which partial or complete cessation of breathing occurs many times throughout the night, resulting in daytime sleepiness or fatigue that interferes with a…
- Trial name
- NCT03142022
- Testing
- No intervention - Diagnostic polysomnography at 1 year after lung transplantation
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obstructive Sleep Apnea
Nexus Compliance Study
Obstructive sleep apnoea (OSA) is characterised by a partial or complete collapse of the upper airway during sleep. The treatment of choice for OSA is Continuous Positive Airway Pressure (CPAP).
- Trial name
- NCT01013207
- Testing
- CPAP Pre Nexus (S9), Nexus (S9), CPAP Post Nexus (S9)
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- ResMed
Sleep-Disordered Breathing, Obstructive Sleep Apnea
Managing Opioid Related Sleep Apnea With Acetazolamide
Patients with chronic pain who use opioids appear to be at increased risk for breathing issues during sleep, termed sleep disordered breathing (SDB).
- Conditions
- Sleep-Disordered Breathing, Obstructive Sleep Apnea, Central Sleep Apnea, Chronic Pain
- Trial name
- MORPHO (NCT06043830)
- Testing
- Acetazolamide
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of California, San Diego
Heart Failure, Sleep Apnea Syndromes
Treatment of Sleep Disordered Breathing In Acute Decompensated Heart Failure Patients
Heart Failure affects 5-6 million Americans and there are about 550 thousand new cases of heart failure every year. There are approximately 3 million hospital admission for acute decompensated heart failure with hospital…
- Trial name
- ARIA-II (NCT00804349)
- Testing
- Autotitrating Positive Airway Pressure
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Albert Einstein Healthcare Network
Sleep Disordered Breathing
Sleep Disordered Breathing, Adenotonsillectomy, Cognition and Pre-school Age Children
Sleep disorder breathing (SDB) is a condition affecting 10% of children aged 2-6 years. It is a combination of snoring most nights during sleep, patchy sleep, short periods of stopping breathing (apnoea) and usually big tonsils.
- Trial name
- NCT02945306
- Testing
- Adenotonsillectomy, Watchful waiting with supportive care
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- South Tees Hospitals NHS Foundation Trust
Sleep Disordered Breathing
Opioid Safety Program in Pain Clinics (Op-Safe):
In this vital study, the investigators will develop an innovative Opioid Safety (Op-Safe) Program for use in pain clinics. The Op-Safe Program consists of two key components: Educating patients with an informative brochure and…
- Trial name
- NCT02513836
- Testing
- Pre-education intervention, Post-education intervention
- Where
- 5 sites in Canada
- Volunteers
- 304 people
- Sponsor
- University Health Network, Toronto
Sleep-Disordered Breathing, Obstructive Sleep Apnea
A Multi-Center Study to Assess the Performance of Saturation Patterns.
A multi-center, prospective, single-visit study designed to acquire physiologic pulse oximeter waveform data during standard polysomnography (PSG) studies performed at multiple different Sleep Lab Centers.
- Conditions
- Sleep-Disordered Breathing, Obstructive Sleep Apnea, Sleep Apnea, Central Sleep Apnea
- Trial name
- NCT00775346
- Where
- 3 sites in United States
- Volunteers
- 92 people
- Sponsor
- Medtronic - MITG
Healthy, Healthy Adult
Assessment of Lung Function (Lufu) at Sea Level LA vs. High Altitude HA in Healthy Individuals
To study the effect of a re-ascent to high altitude (Quito Ecuador: 2850m) after a one-week stay at sea level (after prior descent from 2850m) on lung function and pulmonary resistance/reactance in healthy individuals, who live…
- Conditions
- Healthy, Healthy Adult, High Altitude Effects, High Altitude
- Trial name
- NCT07804537
- Testing
- Re-ascent from sea level to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Elective Coronary Artery Bypass Grafting (CABG) Surgery, Coronary Artery Disease
Sleep-disordered Breathing and Perioperative Atrial Fibrillation in Cardiac Surgery
In patients undergoing elective coronary artery bypass grafting (CABG) surgery, coronary artery disease, sleep-disordered breathing (SDB), atrial fibrillation (AF) perioperative atrial fibrillation and complications will be…
- Conditions
- Elective Coronary Artery Bypass Grafting (CABG) Surgery, Coronary Artery Disease, Sleep-disordered Breathing (SDB), Atrial Fibrillation
- Trial name
- CONSIDER-AF (NCT02877745)
- Testing
- Stratification, no intervention
- Where
- Germany
- Volunteers
- 1,200 people
- Sponsor
- Michael Arzt
Sleep Apnea Syndrome
Pharyngeal Sensitivity in Diagnosis Algorithm for Sleep Apnea Syndrome
Pharyngeal sensitivity is a determinant parameter of pharyngeal functioning, particularly regarding protective dilator reflexes of upper airway.
- Trial name
- SENSITEST (NCT00885573)
- Testing
- Measurement of pharyngeal sensitivity (SENSITEST)
- Where
- 5 sites in France, Switzerland
- Volunteers
- 52 people
- Sponsor
- University Hospital, Grenoble
Pulmonary Arterial Hypertension (PAH), Sleep-disordered Breathing (SDB)
PAH-SDB: Sleep-Disordered Breathing and Outcomes in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a progressive pulmonary vascular disease characterized by increased pulmonary vascular resistance, right ventricular dysfunction, and clinically important morbidity and mortality.
- Trial name
- PAH-SDB (NCT07852403)
- Testing
- Standardized Overnight Sleep and Cardiorespiratory Monitoring
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Sleep Disordered Breathing, Heart Failure
The Effect of CRT on the Hypercapnic Ventilatory Response
Central Sleep Apnoea (CSA) affects up to half of patients with severe heart failure and is associated with a poor prognosis. CSA is manifest as episodes of deep breathing interspersed with very shallow or absent breathing and is…
- Trial name
- NCT02203383
- Testing
- CRT Implantation
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust