Clinical trials: Sleep Disordered-breathing
Preeclampsia, Gestational Diabetes
The Association Between High Risk Pregnancy and Sleep-disordered Breathing
The aim of the present study is to establish, using polysomnographic criteria and prospective nature, whether sleep apnea in pregnancy is more prevalent in women with high risk pregnancies including preeclampsia, gestational…
- Conditions
- Preeclampsia, Gestational Diabetes, Premature Labor
- Trial name
- NCT01022619
- Where
- 2 sites in Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Insomnia, Hypersomnia
Sleep Disorders and Their Cardiovascular Correlates in Atahualpa.
Little is known on the prevalence of sleep disorders and their role in the increased prevalence of cardiovascular diseases in the developing world.
- Conditions
- Insomnia, Hypersomnia, Sleep-disordered Breathing, Stroke
- Trial name
- NCT01877616
- Testing
- diagnostic test
- Where
- Ecuador
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Hospital Clínica Kennedy
Sildenafil, Sleep Apnea
The Effect of Sildenafil on Sleep-Disordered Breathing in Obese Patients With Sexual Dysfunction
Sildenafil has been shown to aggravate sleep-disordered breathing in patients with severe obstructive sleep apnea. The aim of the present study is to examine the frequency of sleep-disordered breathing in obese patients who are…
- Conditions
- Sildenafil, Sleep Apnea, Sexual Dysfunction, Obesity
- Trial name
- NCT00893191
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Sleep Disordered Breathing, Sleep Apnea, Central
Evaluation of the Philips Respironics BiPAP autoSV Devices in Subjects With Sleep Disorders
Comparing two BiPAP autoSV devices in participants with complex sleep apnea and determining if the new device will treat those participants no worse than when compared to its predecessor device.
- Trial name
- NCT01626989
- Testing
- BiPAP auto Advanced, BiPAP auto SV4
- Where
- 3 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Philips Respironics
Apnea, Obstructive
Validation of the French Version of the OSA-18 Questionnaire
Obstructive sleep apnea (OSA) is characterized by repetitive partial and/or total closure of the upper airway during sleep, inducing oxygen desaturation and sleep disturbance. Its prevalence in the pediatric population is 1-5%.
- Trial name
- French OSA18 (NCT07136909)
- Testing
- Completion of the OSA-18 questionnaire by parents, during hospitalization planned as part of routine care.
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Sleep-Disordered Breathing, Sleep Architecture
Screening of OSA in Hospitalized Stroke Patients Using BSP
Obstructive sleep apnea (OSA) is prevalent in patients with stroke and has a negative effect on outcomes by predisposing them to recurrent stroke, increasing mortality, and so forth.
- Conditions
- Sleep-Disordered Breathing, Sleep Architecture, Stroke, Acute
- Trial name
- NCT05466864
- Testing
- Belun Sleep platform
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Sleep-Disordered Breathing, Sleep Architecture
Validation of Belun Ring Gen3 Deep Learning Algorithms With Subxiphoid Body Sensor
Hypothesis: BR's Gen3 DL algorithms, combined with its subxiphoid body sensor, can accurately diagnose OSA, categorize its severity, identify REM OSA and supine OSA, and detect central sleep apnea (CSA).
- Conditions
- Sleep-Disordered Breathing, Sleep Architecture, Arrhythmia
- Trial name
- NCT06255613
- Testing
- Belun Ring, Belun Cor
- Where
- 2 sites in United States
- Volunteers
- 79 people
- Sponsor
- Belun Technology Company Limited
Sleep Disordered Breathing
Pharmacological Intervention for Symptomatic Mild Sleep Disordered Breathing
Currently, there is no pharmacological intervention for mild symptomatic obstructive sleep disordered breathing (SDB) in the form of loud habitual snoring, inspiratory flow limitation (i.e.
- Trial name
- NCT04611750
- Testing
- AD036
- Where
- 2 sites in United States, Australia
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep Related Breathing Disorder, Congestive Heart Failure
Impact of Resynchronization Therapy on Sleep Disordered Breathing in Advanced Congestive Heart Failure
Background and Introduction: SDB is increasingly recognized as a co-morbidity with significant impact on overall health. The disorder has been implicated in the development of hypertension, atherosclerotic cardiovascular disease…
- Trial name
- IMPACT (NCT00521534)
- Testing
- CRT with atrial overdrive pacing
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- VA Pittsburgh Healthcare System
Healthy, Healthy Adult
Assessment of Heart Rate Variability HRV During Descent DE From 2850m to Sea Level and During Re-ascent A From Sea Level to 2850m in Healthy Individuals H
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level and re-ascent from sea level to 2850m on heart rate variability and other hemodynamic parameters in healthy individuals, who live…
- Conditions
- Healthy, Healthy Adult, High Altitude Effects, High Altitude
- Trial name
- NCT07801846
- Testing
- Descent and re-ascent (2850m, sea level)
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Obstructive Sleep Apnea, Sleep-Disordered Breathing
A Short Term Open, Randomized Cross-over Trial Exploring the Effect of Carbonic Anhydrase Inhibition by Acetazolamide on Sleep Apnea Associated Hypertension and Vascular Dysfunction
This is a short term open, randomized cross over trial to explore and compare the efficacy of pharmacological carbonic anhydrase (CA) inhibition on obstructive sleep apnea (OSA) related hypertension.
- Conditions
- Obstructive Sleep Apnea, Sleep-Disordered Breathing, Blood Pressure, Hypertension
- Trial name
- NCT02220803
- Testing
- Acetazolamide, nasal Continuous Positive Airway Pressure (nCPAP)
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Göteborg University
Sleep Disordered Breathing, Obstructive Sleep Apnea
The Evaluation of a Nasal Mask for the Treatment of Obstructive Sleep Apnea (OSA): Comfort & Performance Trial
This investigation is designed to evaluate the performance (treatment and leak), comfort (subjective feedback), stability (subjective feedback, leak) as well as the participant's overall acceptance of the Saturn mask amongst OSA…
- Trial name
- NCT03075722
- Testing
- Saturn nasal mask
- Where
- New Zealand
- Volunteers
- 14 people
- Sponsor
- Fisher and Paykel Healthcare
Heart Failure, Sleep Apnea Syndromes
ECG Derived Respiration for Automated Screening of Sleep Disordered Breathing in Chronic Heart Failure Patients
The prevalence of sleep disordered breathing (SDB) reaches more than 50% in chronic heart failure patients (CHF). The main consequence is an increase risk of fatal and non-fatal cardiovascular events.
- Conditions
- Heart Failure, Sleep Apnea Syndromes, Polysomnography
- Trial name
- NCT02116686
- Testing
- ventilatory polygraphic recordings
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Sleep-Disordered Breathing, Sleep Architecture
Ring-type Pulse Oximeter for Evaluation for Sleep Assessment Study
Recently, various electronic lifestyle activity monitoring devices (ELAM) are increasingly commercially available. However, the quality and reliability of the data from ELAM are unclear, compared with polysomnography (PSG), which…
- Trial name
- ROSA (NCT06221124)
- Testing
- Belun Ring Pulse Oximeter
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Belun Technology Company Limited
Sleep Apnea Syndromes, Snoring
Upper Airway Stability During Wakefulness and Sleep
Negative expiratory pressure is a technique that has been the focus of many studies in the last few years. Airway response to the application of a negative expiratory pressure (NEP) can be used to detect the presence of upper…
- Trial name
- NCT03893552
- Testing
- Negative expiratory pressure
- Volunteers
- 100 people
- Sponsor
- Université Catholique de Louvain
Lung Cancer
Early Diagnosis and Treatment of Sleep Disordered Breathing in Lung Cancer
Sleep-disordered breathing at night is a common medical problem. It leads to daytime fatigue, impairment in concentration and daily activities, and a higher risk of cardiovascular disease and life-threatening events.
- Trial name
- NCT03443908
- Testing
- CPAP
- Where
- United States
- Sponsor
- Mark M. Fuster, MD
Sleep Apnea, Sleep-Disordered Breathing
Alice PDx User/Validation Extended Trial
The objective of this study is to test the usability of the Alice PDx device by both the end user (patient/participant) and the sleep technician.
- Trial name
- NCT00841906
- Testing
- Alice PDx with only written instructions, Alice PDx with written and verbal instructions
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Philips Respironics
Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa), Obstructive Sleep Apnea
Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders
Background: Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is the most common periodic fever syndrome of childhood.
- Conditions
- Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa), Obstructive Sleep Apnea, Tonsillitis, Tonsil Disorder
- Trial name
- NCT05656365
- Where
- 3 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Obstructive Sleep Apnea
Validation of a New Automatic Bi-level Algorithm in the Treatment of Sleep-disordered Breathing
Between 2%-4% of adult population suffers from obstructive sleep apnea (OSAS)(1), which is characterized by obstructive snoring, repetitive apnea and hypopnea in sleep, repetitive cyclic oxygen saturation, as a result from sleep…
- Trial name
- NCT00910195
- Testing
- CPAP treatment with subsequent Bi-Level-APAP treatment, Bi-Level-APAP treatment with subsequent CPAP treatment
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Sleep Disordered Breathing Central, Heart Failure
Prevalence and Dynamic of Sleep-disordered Breathing in Patients Pre and Post Heart Transplantation
Sleep-disordered breathing is believed to appear at a high prevalence in end-stage heart failure patients and the presence of sleep-disordered breathing has been associated with increased mortality.
- Conditions
- Sleep Disordered Breathing Central, Heart Failure, Heart Transplantation
- Trial name
- HTx-HDZ-SDB-1 (NCT03026634)
- Testing
- Sleep-disordered breathing
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia