Clinical trials: Sleep Disorders, Intrinsic
Sleep Initiation and Maintenance Disorders
Lendormin D® Tablet (Drug Use Result Survey)
Study to investigate the safety and the efficacy in patients with insomnia, receiving Lendormin D tablet under condition of normal clinical practice.
- Trial name
- NCT02224014
- Testing
- Lendormin D tablets
- Volunteers
- 485 people
- Sponsor
- Boehringer Ingelheim
Obstructive Sleep Apnea
Usability Evaluation of Menai CPAP Masks
The primary objective of this study is to evaluate the subjective performance of the Menai mask systems (full face, nasal, and pillows variants), compared against Comparison mask systems.
- Trial name
- NCT02364375
- Testing
- Menai mask (full face), Menai Standard mask (full face), Menai mask (nasal)
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- ResMed
Obstructive Sleep Apnea
RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA
The goal of this randomised, double-blind phase II/III clinical trial is to determine the safety and efficacy of IHL-42X in subjects with obstructive sleep apnoea who are intolerant, non-compliant, or naïve to positive airway…
- Trial name
- REPOSA (NCT06146101)
- Testing
- IHL-42X Low Dose, IHL-42X High Dose, IHL-42X (Optimal Dose)
- Where
- 20 sites in United States
- Volunteers
- 121 people
- Sponsor
- Incannex Healthcare Ltd
Tinnitus, Hearing Disorders
Evaluation of Potential Causes of Nap Modulated Tinnitus
The proposed research is a non-interventional study made to evaluate different measurements on 1 group of participants, before and after taking a nap, aiming to potentially guide future investigations on nap-modulated tinnitus to…
- Conditions
- Tinnitus, Hearing Disorders, Ear Diseases, Otorhinolaryngologic Diseases
- Trial name
- TinniNap (NCT05467059)
- Testing
- Napping
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Robin Guillard EIRL
Sleep Apnea
Effects of Suvorexant in Participants With Obstructive Sleep Apnea (MK-4305-036)
This study will evaluate the safety, tolerability, and effect of multiple doses of suvorexant (MK-4305) on respiratory function in participants with mild to moderate obstructive sleep apnea (OSA) compared to administration of…
- Trial name
- NCT01300455
- Testing
- Suvorexant
- Volunteers
- 26 people
- Sponsor
- Merck Sharp & Dohme LLC
Obstructive Sleep Apnea
REV 002 Observational Study of the ReVENT Sleep Apnea System: Minimally Invasive Treatment for Obstructive Sleep Apnea
The purpose of this post-market observational study is to assess the effectiveness and patient perception of benefit of the ReVENT Sleep Apnea System in patients diagnosed with Obstructive Sleep Apnea due to primary tongue base…
- Trial name
- NCT02180815
- Testing
- ReVENT Sleep Apnea System
- Where
- 14 sites in Belgium, Czechia and 3 more
- Volunteers
- 50 people
- Sponsor
- Revent Medical International B.V.
Obstructive Sleep Apnea
Pilairo Lab Market Research
The purpose of the study is to observe the Pilairo mask in a lab setting.
- Trial name
- NCT01824979
- Testing
- CPAP mask ( Pilairo), Other CPAP mask
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Fisher and Paykel Healthcare
Insomnia, Sleep Apnea
Validation of the Dayzz Digital Sleep Training App in Insomnia and Sleep Apnea
The prevalence of sleep disorders has achieved epidemic proportions in Western countries. Despite this, assessment and treatment of sleep disorders remains infrequent, unattainable, and often costly.
- Trial name
- NCT03955120
- Testing
- Dayzz mobile sleep training, Treatment as usual
- Where
- Israel
- Volunteers
- 125 people
- Sponsor
- Dayzz Live Well Ltd.
Sleep Quality, Quality of Lifte
Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Improving Sleep in Visually Impaired Patients
Trial title: Effectiveness of Electrical Vestibular Nerve Stimulation in the Improvement of Sleep in Patients with Visual Impairment.
- Conditions
- Sleep Quality, Quality of Lifte, Non-24 Sleep-Wake Disorder
- Trial name
- NCT06956118
- Testing
- Intervention (VeNS Stimulation) Device
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Neurovalens Ltd.
Insomnia, Insomnia Chronic
An Open-label Trial to Evaluate the Safety and Efficacy of Chloral Hydrate in Patients with Severe Insomnia
The primary aim of this Real-World Evidence trial is to establish whether short-term (2 weeks) treatment of Chloral Hydrate is effective in patients with severe insomnia which is interfering with normal daily life, and where…
- Conditions
- Insomnia, Insomnia Chronic, Chloral Hydrate
- Trial name
- RESTORE (NCT06053840)
- Testing
- Chloral Hydrate
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Pharmanovia
Sleep Apnea Syndromes, Sleep Apnea, Obstructive
Safety and Efficacy of a Hypoglossal Nerve Implant for the Treatment of Obstructive Sleep Apnea (OSA)
The objective of the study is to determine the safety and preliminary efficacy in patients utilizing the aura6000 System for the treatment of Obstructive Sleep Apnea (OSA).
- Conditions
- Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Respiration Disorders, Signs and Symptoms, Respiratory
- Trial name
- NCT01532180
- Testing
- aura6000 System
- Where
- Belgium
- Volunteers
- 14 people
- Sponsor
- ImThera Medical, Inc.
Sleep Apnea Syndromes
Janus Feasibility Study
The purpose of this feasibility study is to assess whether an alternative transvenous lead location affects respiration and airway physiology during a commercial remedē® System or commercial transvenous cardiac device (de novo…
- Trial name
- NCT03985527
- Testing
- Transvenous nerve stimulation
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- Respicardia, Inc.
Restless Legs Syndrome
Observational Study of Sifrol® in Patients With Primary Restless Legs Syndrome (RLS)
Study to evaluate treatment effect of pramipexole on RLS severity as measured by IRLS, CGI-I and RLS-6 and to evaluate the time needed to reach maintenance dose of Pramipexole (PPX)
- Trial name
- NCT02248142
- Testing
- Pramipexole
- Volunteers
- 1,029 people
- Sponsor
- Boehringer Ingelheim
Sleep Quality, Menopausal Symptoms
Sleep Quality in CHIMES (MF101)
Menopausal women often complain of difficulty sleeping and the transition from pre- to postmenopausal status is associated with an incresase in self-reported sleep disturbance.
- Trial name
- NCT00454441
- Testing
- MF101
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bionovo
Sleep Apnea
A Validation Study of the NightOwl Home Sleep Apnea Test
The objective of this study is to evaluate the performance of a miniaturized sleep apnea test, called NightOwl. The system consists of a sensor placed on the fingertip and a cloud-based analytics software.
- Trial name
- NCT04764734
- Testing
- NightOwl
- Where
- 4 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ectosense NV
Sleep Apnea, Sleep-Disordered Breathing
Alice PDx User/Validation Extended Trial
The objective of this study is to test the usability of the Alice PDx device by both the end user (patient/participant) and the sleep technician.
- Trial name
- NCT00841906
- Testing
- Alice PDx with only written instructions, Alice PDx with written and verbal instructions
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Philips Respironics
Narcolepsy
A Phase 3 Study to Evaluate the Efficacy and Safety of Samelisant in Patients With Narcolepsy (AWAKE)
The primary objective of this study is to evaluate the effect of Samelisant on excessive daytime sleepiness (EDS) after 12 weeks of treatment.
- Trial name
- NCT07540364
- Testing
- Samelisant
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Suven Life Sciences Limited
Obstructive Sleep Apnea
Evaluation of a Novel Auto-Adjusting Positive Airway Pressure Algorithm for the Treatment of Obstructive Sleep Apnea Clinical Study
This study aims to assess the effectiveness of an investigational algorithm in the treatment of obstructive sleep apnea.
- Trial name
- NCT06769607
- Testing
- Investigational algorithm, Control algorithm
- Where
- Australia
- Volunteers
- 80 people
- Sponsor
- ResMed
Sleep Initiation and Maintenance Disorders
Efficacy Study of LY2422347 to Treat Insomnia
The purpose of this study is to determine whether a compound known as LY2422347 is effective in treating people diagnosed with primary insomnia (difficulty sleeping with no other significant contributing factor, such as…
- Trial name
- NCT00259311
- Testing
- LY2422347
- Where
- 22 sites in United States
- Volunteers
- 400 people
- Sponsor
- Eli Lilly and Company
Obstructive Sleep Apnea
A Study to Examine the Efficacy of a Therapeutic THX-110 for Obstructive Sleep Apnea
This is a sponsored proof of concept study with the purpose to examine the safety, tolerability and feasibility of THX-110 (Dronabinol (synthetic Δ9-THC) and PEA) for the treatment of adults with Obstructive Sleep Apnea.
- Trial name
- NCT03646552
- Testing
- THX-110
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Neurothera Labs Inc.
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