Clinical trials: Sleep Disorders, Intrinsic
Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA), Hypertension , β1 Subunit of Maxi-k+ Channel and Cardiovascular Risk
To describe the relationship between OSA and clinical Hypertension (performing ABPM), endothelial dysfunction (performing flowmetry), and its relation at the basic research (determining the β1 subunit in Peripheral Leukocytes in…
- Trial name
- OSAS (NCT01791270)
- Testing
- Continuous positive airway pressure (CPAP) therapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Angeles Sanchez Armengol
Sleep Apnea Syndromes, Sepsis
Impact of Sleep Apnea on Sepsis Mortality
By clinical record review, this retrospective study aims to compare the mortality of sepsis patients with versus without obstructive sleep apnea, who were diagnosed and treated in Taipei Veterans General Hospital, Taiwan.
- Conditions
- Sleep Apnea Syndromes, Sepsis, Mortality
- Trial name
- NCT03654456
- Testing
- OSA
- Where
- Taiwan
- Volunteers
- 280 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Sleep Apnea, Obstructive, Sleep Apnea, Central
Application of Forced Breath Technique While CPAP Therapy for Apnea Classification
This study analyzes the application of the Forced Breath Technique (FBT) to classify apneas during CPAP therapy with a prismaLAB (device name) therapy device.
- Trial name
- FBT-CPAP (NCT03432910)
- Testing
- CPAP Titration using a Bilevel S/T mode with minimal pressure support and background rate
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Heinen und Löwenstein GmbH & Co. KG
Wheel-chair Dependent Elders
Improvement and Mechanism of Wheel-chair Music Aerobic Exercise on Depression and Insomnia Among the Elderly in Long-term Care Facilities
Investigators anticipate to develop a customized WC-MAE for the improvement of insomnia and depression in wheel-chair dependent elders, and to identify related mechanisms as biomarkers for prediction and prevention of insomnia…
- Trial name
- NCT02256020
- Testing
- Original lifestyle, Wheel-chair music aerobic exercise (WC-MAE)
- Where
- Taiwan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Chang Bing Show Chwan Memorial Hospital
Treatment of Excessive Daytime Sleepiness in Narcolepsy
Effects of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy.
3. RATIONALE FOR BF2.649 IN NARCOLEPSY Narcolepsy is a disabling syndrome affecting the generation and organizations of sleep and wakefulness, first described by Westphal and Gelineau in 19th century.
- Trial name
- NCT01638403
- Testing
- BF2.649, Vigil, palcebo
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Bioprojet
Disc Herniation
The Effect of White Noise in Patients Undergoing Lumbar Disc Herniation Surgery
The aim of this clinical trial is to determine the effectiveness of listening to white noise on the sleep quality, comfort level, satisfaction level of patients after lumbar disc herniation surgery.
- Trial name
- NCT05687305
- Testing
- White Noise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Insomnia, TBI (Traumatic Brain Injury)
Behavioral Treatment of Insomnia in Active-Duty Service Members With Traumatic Brain Injury
The objective of the study is to conduct a randomized controlled trial of Cognitive Behavioral Therapy for Insomnia (CBT-I) in a sample of active-duty sailors with a history of traumatic brain injury (TBI).
- Trial name
- CBTBI (NCT06867666)
- Testing
- In Person CBT-I, CBT-I via COAST
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Noctem, LLC
Sleep Apnea, Obstructive, Tonsillitis
Laryngeal Mask Airway in Pediatric Adenotonsillectomy
The study will compare how often the tubing kinks when a LMA (laryngeal mask airway) with modified retractor is used compared to use of an endotracheal tube (ETT) and non modified retractor is used.
- Trial name
- LMA (NCT01695980)
- Testing
- ETT with non modified retractor, LMA with modified retractor
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Eastern Virginia Medical School
Obesity Hypoventilation Syndrome
Toffee Full Face and Toffee Nasal Mask Evaluation in Obesity Hypoventilation Syndrome (NZ)
This investigation is to evaluate the performance, comfort and ease of use of the Toffee full face and toffee nasal mask masks amongst Obesity Hypoventilation Syndrome (OHS) patients in an overnight study.
- Trial name
- NCT02486380
- Testing
- Toffee full face mask/toffee nasal mask
- Where
- New Zealand
- Volunteers
- 4 people
- Sponsor
- Fisher and Paykel Healthcare
Insomnia
Combined Effects of Prunus Cerasus and Apocynum Venetum On Sleep and Anxiety in Adults With Insomnia
Lay Summary: This study is about the effect of using a unique formula called Sip2Sleep®, a product currently available on the market which is a combination of montmorency tart cherry extract and Venetron® (Apocynum venetum leaf…
- Trial name
- Sip2Sleep (NCT06299488)
- Testing
- Sip2Sleep: Montmorency Cherry and Apocynum Venetum
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Lakshmi Nutraceuticals LLC
COPD, Insomnia
Colorado Marijuana Users Health Cohort
In Colorado, marijuana is currently used for both recreational and medicinal purposes.To learn more about the positive and negative long term medical effects of marijuana use.
- Conditions
- COPD, Insomnia, Cannabis
- Trial name
- NCT02735954
- Testing
- Marijuana
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Insomnia, Insomnia Disorder
Internet-based Treatment for Chronic Insomnia
Study Objectives. Despite effective cognitive behavioral treatments for chronic insomnia, such treatments are underutilized. This study evaluates the impact of a 6-week, online treatment for insomnia.
- Trial name
- NCT00821041
- Testing
- Cognitive Behavioral Therapy
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- University of Manitoba
Obstructive Sleep Apnea (OSA)
Heart and Brain Blood Flow in Obstructive Sleep Apnea
Obstructive sleep apnea causes repeated pauses in breathing during sleep. Breathing efforts against an occluded airway may change how blood flows through the heart and how blood drains from the brain.
- Trial name
- OSA4DFlow (NCT07913269)
- Where
- 2 sites in Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sleep Apnea, Sleep Apnea, Obstructive
Effect Of Sleep Apnea Treatment On Temporo-Mandibular Disorders
Aims of this research are to detect if an improvement in sleep pattern in patients suffering from obstructive sleep apnea (OSA), produces a reduction in pain and dysfunction in the orofacial area by examining variation in…
- Conditions
- Sleep Apnea, Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Pain
- Trial name
- NCT04948541
- Testing
- osa treatment, no treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Anna Alessandri Bonetti
Sleep Onset Insomnia
Effect of Background Noise on Sleep Quality
Insufficient and low-quality sleep is a major public health problem that has been linked to motor vehicle crashes, industrial disasters, and medical and other occupational errors.
- Trial name
- Noise (NCT02945254)
- Testing
- NIghtingale (R) device for filtered white noise (Cambridge Sound Management, Waltham, MA)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea
Patient Perception Questionnaire Validation
Validation of the patient perception questionnaire relating to CPAP use
- Trial name
- NCT02067000
- Testing
- Obstructive Sleep Apnea
- Where
- United States
- Volunteers
- 217 people
- Sponsor
- Fisher and Paykel Healthcare
Hypertension, Sleep Apnea
Losartan in Hypertensive Men and Women With Sleep Apnea Before and on Continuous Positive Airway Pressure (CPAP) Treatment
Obstructive sleep apnea (OSA) is a highly prevalent condition in hypertensive patients. The renin-angiotension-aldosterone-system (RAAS) has a central role in blood pressure control.
- Trial name
- LosartanPAP (NCT00701428)
- Testing
- Losartan, CPAP
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Skaraborg Hospital
Exercise Recovery
Training Health Recovery and Improvement Via Levagen+® Evaluation
INTRODUCTION: Sports supplements and ergogenic aids are widely used for performance enhancement in recreational and professional sports.
- Trial name
- THRIVE (NCT07359534)
- Testing
- Levagen+® Palmitoylethanolamide (PEA)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Westminster
Sleep Disorders, Circadian Rhythm
Effects of Vitamin B12 on the Body's Internal Clock
Circadian rhythms are 24-hour cycles that influence natural functions in the body such as heart rate, blood pressure, and body temperature. Circadian rhythms provide the body with an internal clock and affect sleep patterns.
- Trial name
- NCT00120484
- Testing
- Vitamin B12
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea
Patient Education and PAP Compliance in OSA
Obstructive sleep apnea (OSA) is a common disorder with serious complications. Positive airway pressure (PAP) is the first line treatment of OSA, which eliminates obstructive events, reduces daytime sleepiness, and improves…
- Trial name
- NCT02756299
- Testing
- Educational Support, Standard Support
- Volunteers
- 115 people
- Sponsor
- Marmara University
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