Clinical trials: Sleep Disorders, Intrinsic
Sleep Apnea Hypopnea Syndrome, Physical Activity
Effect of an Aerobic Exercise Program in Patients With Moderate-severe Sleep Apnea
In this paper, it is postulated that in sedentary patients with moderate-severe sleep apnea diagnosed by a sleep test, an increase in physical activity stimulated by the use of a pedometer during a period of 6 months can reduce…
- Trial name
- SAH-2014 (NCT03997877)
- Testing
- Physical activity
- Where
- Spain
- Volunteers
- 176 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Tinnitus
FR-taVNS Tinnitus Tria
Tinnitus is a common neurosensory symptom affecting 12-30% of adults and is closely associated with anxiety, sleep disturbance, and autonomic dysregulation.
- Trial name
- NCT07711639
- Testing
- True Foot Reflexology, True ta-VNS, True Auricular Acupressure
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Tzu Chi University
Restless Legs Syndrome
A Study to Evaluate the Efficacy and Safety of Cabergoline Compared With Placebo for the Treatment of RLS
The purpose of this study is to evaluate the efficacy and safety of cabergoline compared with placebo on periodic leg movements (PLMS) arousl index and sleep efficiency in patients with RLS.
- Trial name
- NCT00627003
- Testing
- Cabergoline
- Volunteers
- 43 people
- Sponsor
- Pfizer
Obstructive Sleep Apnoea (OSA), Hypoventilation Syndrome
Sleep-disordered Breathing Database
The goal of this study is to collect clinical data on patients who have had a sleep study and are given a diagnosis of a sleep related breathing disorder such as obstructive sleep apnoea.
- Trial name
- NCT07402603
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Obstructive Sleep Apnea
Nasal Budesonide in Children With Rhinitis and/or Mild Obstructive Sleep Apnea Syndrome
-Intranasal budesonide therapy may lead to improved symptoms and sleep study findings in children with mild obstructive sleep apnea with and without allergic rhinitis that would not be treated with T\&A.
- Trial name
- NCT00560586
- Testing
- Budesonide
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Louisville
Cancer, Insomnia Chronic
Device Feasibility and Acceptability to Improve Insomnia in Cancer
Sleep disruption is common among young adult cancer survivors for a variety of reasons. Cognitive behavioral therapy for insomnia (CBT-I) has been shown to improve chronic sleep disorders.
- Trial name
- NCT05875129
- Testing
- VAVA prototype
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medstar Health Research Institute
Rheumatic Diseases
A Study on Health - Related Quality of Life in Patients With Rheumatic Diseases Taking Tramadol 37.5mg/Acetaminophen 325mg Tablets
The objective of this observational study is to assess improvement of quality of life in the patients who are administered Tramadol 37.5mg/Acetaminophen 325mg tablets for 10~14 weeks according to the investigator's discretion in…
- Trial name
- NCT00642837
- Testing
- Tramadol/acetaminophen
- Volunteers
- 982 people
- Sponsor
- Janssen Korea, Ltd., Korea
Sleep Disordered Breathing, Obstructive Sleep Apnea
The Natural History and Outcome of Sleep Disordered Breathing in Children
Sleep-disordered breathing in children is characterized by recurrent events of partial or complete upper airway obstruction during sleep, resulting in disruption of normal gas exchange (intermittent hypoxia and hypercapnia) and…
- Trial name
- NCT02043353
- Where
- Israel
- Volunteers
- 2,856 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Decrease of Inflammation of Adipose Tissue, Sleep Apnea Syndrome
Inflammation and Oxidative Stress of Adipose Tissue in Sleep Apnea Syndrome
The main objective of this study is to evaluate the decrease of inflammation of adipose tissue in obese and non-obese patients having a sleep apnea syndrome and treated or not by continuous positive airway pressure (cPAP).
- Trial name
- ADISAS (NCT01196845)
- Testing
- cPAP
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Chronic Kidney Diseases, OSAS (Obstructive Sleep Apneas Syndrome)
The Outcome of Chronic Kidney Disease Patients With Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea (OSA) is highly prevalent in chronic kidney disease (CKD) patients and strongly linked to obesity, metabolic syndrome, and type 2 diabetes.
- Trial name
- NCT06971874
- Testing
- No intervention
- Where
- China
- Volunteers
- 356 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Obstructive Sleep Apnea
Lifestyle Modification Program to Treat Obstructive Sleep Apnea Patients
Obstructive sleep apnea syndrome (OSAS) is a common form of sleep-disordered breathing (SDB) characterized by repetitive episodes of cessation of breathing during sleep due to upper airway collapse.
- Trial name
- OSA (NCT01384760)
- Testing
- Lifestyle modification, Simple lifestyle advice
- Where
- China
- Volunteers
- 185 people
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea
Hypnotics to Improve Polysomnography Yield: Eszopiclone vs Ramelteon?
This study is being conducted to determine if eszopiclone is as effective as ramelteon when used as a pre-medication (sleeping pill) in sleep studies performed to diagnose and treat sleep apnea.
- Trial name
- NCT00811746
- Testing
- Rozerem (Ramelteon), Lunesta (Eszopiclone), Historical Controls
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Southern California Institute for Research and Education
Multiple Sclerosis, Obstructive Sleep Apnea
Prevalence and Impact of Obstructive Sleep Apnea in Multiple Sclerosis
This study will evaluate the influence of sleep apnea on clinical and radiological features of MS. Sleep apnea is associated with hypoxemia during sleep, which is likely detrimental to MS.
- Trial name
- SOMNUS (NCT04603196)
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Beth Israel Deaconess Medical Center
Chronic Pelvic Pain Syndrome (CPPS)
Kinesiophobia, Physical Activity, Sleep, and Quality of Life in Women With Chronic Pelvic Pain
The study will include women who present to the Obstetrics and Gynecology outpatient clinic of Kırşehir Ahi Evran Training and Research Hospital with complaints of pelvic pain and are diagnosed with PCAS after a detailed…
- Trial name
- NCT07833280
- Testing
- questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ahi Evran University Education and Research Hospital
Advanced Malignant Solid Neoplasm, Delirium
Suvorexant for Insomnia to Prevent Delirium in Hospitalized Cancer Patients
This phase IV trial compares suvorexant with standard of care to standard of care alone for improving difficulty sleeping (insomnia) and reducing confusion (delirium) in hospitalized cancer patients.
- Conditions
- Advanced Malignant Solid Neoplasm, Delirium, Hematopoietic and Lymphatic System Neoplasm, Insomnia
- Trial name
- NCT06834386
- Testing
- Best Practice, Electronic Health Record Review, Interview
- Where
- United States
- Sponsor
- Mayo Clinic
Sleep Apnea, Obstructive
Treatment Study of Soft Palatal Implants in Obstructive Sleep Apnea
The purpose of the study is to compare the effectiveness of soft palatal implants with placebo and continuous positive airway pressure treatment in obstructive sleep apnea.
- Trial name
- NCT00263770
- Testing
- soft palate implant, Positive airway pressure (PAP)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Mayo Clinic
Sleep Initiation and Maintenance Disorders, Depression
Improving Sleep and Psychological Functioning in People With Depression and Insomnia
This study will evaluate the safety and effectiveness of treatment with both a sleeping pill and antidepressant medication in improving sleep and psychological functioning in people with depression and insomnia.
- Trial name
- NCT00247624
- Testing
- Eszopiclone, Fluoxetine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Severe Obstructive Sleep Apnea (Apnea Hypopnea Index > 30 Events/Hour), Hypertension
Study of Cardiovascular Disease and Obstructive Sleep Apnea
The purpose of this study is to determine if two medicines (allopurinol and losartan) can influence heart and blood vessel health compared to placebo in patients with sleep apnea who are using continuous positive airway pressure…
- Trial name
- CVD/OSA (NCT01637623)
- Testing
- Losartan, Allopurinol
- Where
- 4 sites in United States
- Volunteers
- 87 people
- Sponsor
- University of Wisconsin, Madison
Insomnia
Driving Performance After Middle of the Night Administration of 3.5 mg Zolpidem Tartrate Sublingual Tablet
A study in healthy volunteers of the next morning driving performance after middle-of-the-night dosing of 3.5 mg zolpidem tartrate sublingual tablet, a sleep aid.
- Trial name
- NCT01106859
- Testing
- zopiclone, zolpidem tartrate sublingual tablet
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Transcept Pharmaceuticals
Obstructive Sleep Apnea, PTSD
Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD
Approximately 20 million Americans suffer from Obstructive Sleep Apnea (OSA) creating risks for major health problems, including dementia, heart attack, and stroke.
- Conditions
- Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
- Trial name
- NCT02641496
- Testing
- CBT-OSA, Sleep Education
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
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