Clinical trials: Sleep Disorders
Sleep Deprivation, Hypoxia
Effect of Acute Sleep Restriction on Responses to Hypoxia
At altitude, humans are exposed to environmental hypoxia induced by the decrease in barometric pressure. On duty or in training, mountain troops, paratroopers or aircrew are regularly exposed to altitude.
- Trial name
- HypSom (NCT05563688)
- Testing
- Hypoxia exposure, Sleep deprivation, Cognitive tasks
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Sleep Disorder (Disorder)
The Effect of NP-2006 on Sleep Quality and Health
The main objective will be to assess the effect of NP-2006 on sleep efficiency in volunteers presented with persistent subclinical insomnia
- Trial name
- NCT07485959
- Testing
- NP-2006
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hanpoong Nature Pharm Co., Ltd.
Alcohol Use Disorder
The Effects of Sex Hormones and Alcohol on Sleep
Rates of heavy drinking and Alcohol Use Disorder (AUD) are increasing in women, but research on alcohol-related harms in women - including alcohol's impact on sleep - has been minimal.
- Trial name
- NCT06143059
- Testing
- Ethanol, Saline
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia, Dental Caries
Bedtime Routines and Children's Health
In Taiwan, the prevalence of sleep problems, myopia, and dental caries in school-age children is high. Little is known regarding the implementation of oral and vision health outcomes around bedtime.
- Conditions
- Myopia, Dental Caries, Sleep, Asthenopia
- Trial name
- NCT05201924
- Testing
- Bedtime routine, Control
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University
Sleep Bruxism, Masseter Muscle Hypertrophy
Changes in Electromyographic Activity in Aligner Treatment of Adult Patients With and Without Nocturnal Bruxism
The purpose of the study is to evaluate the effectiveness of clear aligners on the symptoms and signs reported by bruxism patients.
- Conditions
- Sleep Bruxism, Masseter Muscle Hypertrophy, Grinding Teeth
- Trial name
- EMG_BRUX (NCT06343194)
- Testing
- Bruxoff ®
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Depression, Sleep Disorders, Circadian Rhythm
Longitudinal Ecological Study on Sleep-Wake Patterns in MDD Using Actigraphy
The proposed study will include a longitudinal ecological study (Study 1) and a randomised controlled trial (Study 2). The aims will be to (1) identify the sleep-wake profiles in individuals with Major Depressive Disorder (MDD)…
- Trial name
- NCT06233422
- Testing
- No intervention involved
- Where
- Hong Kong
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Sleep Disturbance, Mental Health Issue
Sweet Scents to Sweet Dreams
The purpose of this study is to determine the effect of herbal pillows on sleep and quality of life in a healthy population using actigraphy, validated questionnaires and daily diary logs.
- Trial name
- SSS (NCT06247696)
- Testing
- Herbal Pillows
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Insomnia, Sleep Disturbance
Exploration of Relationships Between Sleep, Gut Health and Cognition
Our study aims to build on emerging evidence showing relationships between gut health, sleep and brain functions. To achieve this, our study aims to test the feasibility of using non-pharmacological interventions: a…
- Trial name
- NCT05315986
- Testing
- Saffr'Inside; 30mg, Enhanced Sleep Education
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Sleep Quality
EFT AND SLEEP QUALITY
The purpose of this clinical study is to determine whether the application of EFT (Emotional Freedom Techniques) is effective in reducing sleep problems among university students.
- Trial name
- EFT STUDENT (NCT06434454)
- Testing
- EFT Group:Emotional Free Technıcal
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Sleep Wake Disorders, Sleep Disorders, Circadian Rhythm
Biomarkers for Circadian Timing in Healthy Adults
Study investigators want to learn more about the underlying biological clock and to see if the timing of that clock can be estimated from a single blood sample.
- Conditions
- Sleep Wake Disorders, Sleep Disorders, Circadian Rhythm, Sleep Disorders, Intrinsic, Advanced Sleep Phase Syndrome (ASPS)
- Trial name
- NCT03956745
- Testing
- sleep-wake timing, constant routine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea
Inspire Home Study: Utilization of Home Monitoring During Therapy Optimization in Patients With an Inspire Upper Airway Stimulation System (Comparison of Home Sleep Testing vs. In-lab Polysomnography Testing)
Inspire intends to conduct this study to compare Apnea-Hypopnea Index (AHI), between the two randomization arms, at 6 months post-activation
- Trial name
- HOME (NCT04416542)
- Testing
- Home Sleep Testing
- Where
- 5 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Inspire Medical Systems, Inc.
Restless Legs Syndrome
Drug Drug Interaction Study With Gabapentin Enacarbil and Morphine
This double-blind study will evaluate the pharmacokinetics of a single dose of morphine or gabapentin derived from gabapentin enacarbil (GEn) after administration of morphine and GEn alone and in combination as well as the…
- Trial name
- NCT01476124
- Testing
- GEn 600 mg, Morphine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- XenoPort, Inc.
Conditions Influencing Health Status, Body Weight
Body Composition, Nutritional and Cardiovascular Status and Lifestyle Factors of Adults Who Are on Plant-Based Diet
There is an objective lack of data on the body composition, nutritional status, cardiovascular status and lifestyle of adults on a plant-based diet (PBD).
- Conditions
- Conditions Influencing Health Status, Body Weight, Lipid Metabolism Disorders, Uricemia
- Trial name
- SuppWFPBD (NCT03976479)
- Testing
- Body composition, questionnaires, biochemistry and blood pressure results
- Where
- Slovenia
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Boštjan Jakše
Sleep Deprivation, Sleep
Sleep Deprivation's Regulation of Immune System Function and Behavior
The study proposes to investigate whether sleep deprivation will affect a variety of measures, including hormones, immune system functioning, and behaviors related to food intake and hunger.
- Trial name
- SS (NCT01730742)
- Testing
- Neuroeconomics task, Portion Size Task, Blood sample
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Complementary and Alternative Therapies, Aging
The Effect of Music on Sleep Quality and Comfort in Elderly: A Randomized Controlled Trial
The aim of this clinical study is to examine the effects of music on sleep quality and comfort levels in individuals aged 65 and older.
- Conditions
- Complementary and Alternative Therapies, Aging, Geriatric, Sleep Disorder in Elderly
- Trial name
- NCT06843941
- Testing
- Music intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ege University
Dry Eye Disease
Eye Mask on Sleep Quality and Tear Layer Function in Patients With Dry Eye Disease
This randomized clinical trial (RCT) was aimed to determine the effects of eye masking on sleep quality and tear layer function in patients with dry eye disease.
- Trial name
- NCT06016166
- Testing
- Eye mask
- Where
- Iran
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hamideh Sabbaghi
Autonomic Nervous System Diseases, Sleep
Sleep, Autonomic Nervous System and Cardiorespiratory Capacity in Autism Spectrum Disorders Children (APAUTRES)
Autism Spectrum Disorders (ASD) is a neurodevelopmental disorder which involves social and behavioural impairments. Autonomic dysfunctions and disturbed sleep were often associated to ASD.
- Trial name
- APAUTRES (NCT02830022)
- Testing
- physiological explorations
- Where
- France
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Sleep Apnea Syndromes
The Number and Function of Regular T Cell in Patients With Obstructive Sleep Apnea
To compare the number and function of regular T cell of patients with obstructive sleep apnea (OSA) versus that of age-, gender- and BMI (body mass index)-matched controls
- Trial name
- NCT02342028
- Testing
- OSA
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Schizophrenia
Effects of Eszopiclone on Sleep and Memory in Schizophrenia
The investigators will test the hypothesis that the sleep medication, eszopiclone, can normalize brain activity during sleep and improve memory in patients with schizophrenia.
- Trial name
- NCT01641900
- Testing
- eszopiclone
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Sleep Disorders, Circadian Rhythm
Nursing Activity and Quality of Hospitalized Patients' Sleep
This study is to determine the impact of night shift nurse's activity on patients' sleeping patterns in medical services including individual, clinical and environmental factors.
- Trial name
- SOMACTIV (NCT03370354)
- Testing
- Observational
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
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