Clinical trials: Sleep Disorders
Apnea
A Study of Breathing Sound-based Classification of Patients With Breathing Disorders
Sleep-disordered breathing can damage the cardiovascular system, and may also lead to dysregulation of the autonomic nervous system, endocrine disorders, and hemodynamic changes, causing multi-system and multi-organ damage.
- Trial name
- NCT05868694
- Testing
- polysomnography
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Huai'an No.1 People's Hospital
Mental Health Wellness 1, Sedentary Behavior
Health Parameters of University Students After Pandemic Isolation
The COVID-19 pandemic caused by the SARS-CoV-2 coronavirus represents threats to global health and economy. The high pathogenesis of SARS-CoV-2 extent that the Mexican government declared a national health emergency, agreeing to…
- Trial name
- NCT05282537
- Testing
- In person academic activities
- Where
- Mexico
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Obstructive Sleep Apnea (OSA)
Development of Advanced Leak Detection Technologies for Positive Airway Pressure Devices Therapies
This study will take between 1-2 months (with first patient first visit to last patient last visit). Each participant will use the supplied PAP device and mask for a period of up to 14 nights.
- Trial name
- NCT04741854
- Testing
- Positive Airway Pressure (PAP) Therapy
- Where
- Australia
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- ResMed
Chronic Pain, Chronic Insomnia
Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain
The goal of this study is to test two behavioral interventions for chronic insomnia in individuals with chronic pain and use prescribed opioid medication to treat their chronic pain.
- Conditions
- Chronic Pain, Chronic Insomnia, Opioid Use
- Trial name
- NCT06345872
- Testing
- CBT-I, Treatment as usual, Tapered Withdrawal
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Gastroesophageal Disease
To Determine if Sleep Deprivation Results in Increased Esophageal Acid Exposure
The purpose of this study is to determine if sleep deprivation results in increased esophageal acid exposure in healthy controls and gastroesophageal reflux disease (GERD) patients.
- Trial name
- IRUSESOM0428 (NCT01093339)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Southern Arizona VA Health Care System
Sleep, Newborn
Effects of Music-Based Interventions on Sleep Patterns and Physiological Responses in Premature Newborns: A Systematic Review and Meta-Analysis
Sleep in the neonatal period is a fundamental biological requirement for regulating growth, neurodevelopment, and the immune system.
- Trial name
- NCT07127419
- Volunteers
- 1,415 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Obstructive Sleep Apnea
Right Ventricular Function in Patients With Obstructive Sleep Apnea
The purpose of this study is to determine whether patients with obstructive sleep apnea have any changes in right ventricular function evaluated by three dimensional echocardiography.
- Trial name
- NCT01201200
- Where
- Brazil
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Recurrent Tonsillitis, Peritonsillar Abscess
Auricular Acupuncture for The Treatment of Post-Tonsillectomy Pain
The goal of this study is to assess the role of battlefield acupuncture in the reduction of pain scores status post adult tonsillectomy.
- Conditions
- Recurrent Tonsillitis, Peritonsillar Abscess, Obstructive Sleep Apnea
- Trial name
- NCT01790477
- Testing
- Auricular Acupuncture
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Aging, Mental Disorder
Self-Care for Dementia Caregivers
The Self-care for Dementia Caregivers Study is a behavioral health intervention that uses digital monitoring tools and motivational health coaching to help caregivers of persons with dementia engage in a regular routine of sleep…
- Conditions
- Aging, Mental Disorder, Eating, Healthy, Physical Inactivity
- Trial name
- Care2 (NCT05309577)
- Testing
- Behavioral Self-Monitoring + Motivational Interviewing
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Intensive Care Unit Syndrome, Prediction
Machine Learning-based Longitudinal Study of Post-ICU Syndrome Development Trajectory in Critically Ill Patients and Construction of Clinical Early Warning Models: a Research Protocol for Longitudinal Study
This project intends to track and evaluate whether post-ICU syndrome will occur 7 days, 1 month, 3 months and 6 months after ICU patients are transferred out of the ICU through a longitudinal study, apply the latent category…
- Conditions
- Intensive Care Unit Syndrome, Prediction, Cognitive Impairment, Sleep Disorder
- Trial name
- NCT06427265
- Where
- China
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital Of Guizhou Medical University
Sleep Disorder; Breathing-Related, Pain
Prospective Randomized Trial of CPAP for SDB in Patients Who Use Opioids
Patients with chronic pain who use opioids appear to be at increased risk for breathing issues during sleep, termed sleep disordered breathing (SDB).
- Conditions
- Sleep Disorder; Breathing-Related, Pain, Sleep Apnea, Obstructive Sleep Apnea
- Trial name
- PRESTO (NCT04928157)
- Testing
- Positive Airway Pressure (PAP)
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obstructive Sleep Apnea, Tonsillitis
Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery
A RCT to compare hydromorphone versus fentanyl for pain control following tonsillectomy or adenotonsillectomy surgery.
- Trial name
- NCT04230681
- Testing
- Hydromorphone, Fentanyl
- Where
- United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Sleep, Sleep Deprivation
Sleep Loss and Glucose Metabolism in People With Family History of Type 2 Diabetes.
The use of sugar and starch-like foods for energy (carbohydrate metabolism) changes when people sleep. However, it is still not known if differences in the amount of nighttime sleep have an effect on the carbohydrate metabolism…
- Conditions
- Sleep, Sleep Deprivation, Insulin Resistance, Type 2 Diabetes
- Trial name
- NCT00721019
- Testing
- 5-hour bedtime, 8.5-hour bedtimes
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Chicago
HIV Infections, Frailty
Sleep Quality and Frailty Among People Living With HIV
With effective antiretroviral therapy (ART), people living with HIV (PLWH) are living longer and are increasingly experiencing aging-related conditions such as frailty and sleep problems.
- Conditions
- HIV Infections, Frailty, Sleep Quality, Oral Frailty
- Trial name
- NCT07880054
- Testing
- No intervention (observational assessments)
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Sun Yat-sen University
Sleep Bruxism, Childhood
Sleep Hygiene Measures for Sleep Bruxism in Children
The aim of the study is to evaluate the efficacy of sleep hygiene measures for the possible improvement of sleep bruxism in children through a randomized controlled clinical study of children under 8 years of age with probable…
- Trial name
- NCT04501237
- Testing
- Bruxers with sleep hygiene instructions
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Healthy Volunteers, Alcohol Use Disorder (AUD)
Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms
Background: Alcohol use disorder (AUD) is a leading cause of disease and death worldwide. New treatments for AUD are needed. Dopamine, a chemical that carries signals between brain cells, is thought to play a role in alcohol…
- Trial name
- NCT06484075
- Testing
- Siemens 3T PRISMA MR Scanner, PET/CT Scanner, Suvorexant
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Overweight and Obesity, Health Behavior
Location-based Smartphone Technology to Guide College Students Healthy Choices Ph II
College students are in a newly independent phase of life; many of whom encounter unhealthy dietary decision- making, barriers to physical activity, and poor sleep behaviors.
- Conditions
- Overweight and Obesity, Health Behavior, Sleep Deprivation
- Trial name
- NCT02996864
- Testing
- Healthy Detours App, Fat Secret App
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Brain Injuries, Traumatic, Post-traumatic Stress Disorder
Morning Bright Light to Improve Sleep Quality in Veterans
One of the principal complicating factors associated with traumatic brain injury (TBI) is sleep-wake disturbances (e.g., insomnia, excessive daytime sleepiness, and circadian rhythm sleep disorders).
- Trial name
- NCT03578003
- Testing
- Morning Bright Light Therapy
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Portland VA Medical Center
Jet Lag Disorder, Jet Lag
A Study on the Effectiveness of a Dietary Supplement FitoAvia for Jet Lag
Purpose of the study: Evaluation of the effects of dietary supplement Fitoavia in people with dyssynchrony Objectives of the study: 1. Assessment of the condition of patients with jet lag of 4 hours or more 2.
- Conditions
- Jet Lag Disorder, Jet Lag, Jet Lag Type Insomnia, Cognition Improvement
- Trial name
- NCT07695870
- Testing
- Fitoavia, Questionnaire and Physical Exam, cognition tests
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MiraxBioPharma
Epilepsy
Embrace: Seizure Characterization
The study is intended to characterize sleep, stress, and seizures in daily life with the Empatica Embrace watch and smartphone-based diary-alert system.
- Trial name
- NCT03206502
- Testing
- Embrace + Alert App
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Empatica, Inc.