Clinical trials: Sleep Disorders
Bruxism, Bruxism, Sleep-Related
Diaphragmatic Breathing for Sleep Bruxism in Adults: A Randomized Controlled Trial
The goal of this clinical trial is to learn if a diaphragmatic breathing program can reduce sleep bruxism in adults. The main questions it aims to answer are: Can diaphragmatic breathing lower the frequency of teeth grinding…
- Trial name
- DB4SB (NCT07181642)
- Testing
- Diaphragmatic Breathing Program, Neutral Music Listening
- Where
- Tunisia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Prehypertension, Hypertension
HELP-HY: Health Education and sLeep Program in HYpertension
Hypertension is the major risk factor for cardiovascular and cerebrovascular diseases worldwide. The escalating prevalence of inadequate sleep now parallels that of hypertension.
- Trial name
- NCT03255746
- Testing
- Sleep Enhancement, Health Education
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
OSA
Impact of Intermittent Hypoxia on Neutrophil Extracellular Traps
This prospective observational study will enroll 60 moderate-to-severe OSA patients (AHI≧15/hour, 30 obese [BMI>=27] \& 30 non-obese [BMI<27]) and 40 age-, gender-, BMI-matched controls without OSA.
- Trial name
- NCT05485688
- Testing
- sleep apnea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Sleep, Cardiovascular Disease
Impact of Sleep Restriction in Women
The overall goal of this project is to test the hypothesis that long-term, sustained sleep restriction (SR), in women, will lead to increased cardio-metabolic risk.
- Conditions
- Sleep, Cardiovascular Disease, Obesity
- Trial name
- NCT02835261
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Columbia University
Insomnia
The Assessment of Human Sleep and Its Functions
The purpose of this study is to look at the effects of targeted brain stimulation when falling asleep and on sleep quality.
- Trial name
- SS_Sleep (NCT07211646)
- Testing
- Fixed tES, Personalized tES
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- StimScience Inc.
Weight Gain
Sleep-Safe: A Strong African American Families Study
Rapid weight gain during infancy is a powerful, and potentially malleable, risk factor for later overweight and obesity, but limited research has examined the impact of promising interventions when applied to the groups most at…
- Trial name
- NCT03505203
- Testing
- Sleep Soothe, Sleep Safe
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Attention Deficit Disorder With Hyperactivity
Sleep and Memory Consolidation in Adults With Attention Deficit Hyperactivity.
Attention Deficit Disorder With Hyperactivity is associated with deficits in cognition and sleep. In healthy adults, memory consolidation processes are related to sleep spindle activity in the sleep electroencephalogram.
- Trial name
- HYPNOS (NCT05876286)
- Testing
- Neurological examinations
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Sleep Apnea Syndromes
Cardiovascular Impact, Quality e Quantity of Sleep in Bed Partners of Patients With Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a common clinical condition associate with a negative impact not limited to the patients but also to the partner that sleep in the same bed.
- Trial name
- SLEEP-PARTNERS (NCT03011294)
- Testing
- Continuous positive airway pressure (CPAP), Nasal strip
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Moderate to Severe Insomnia
HALO Clarity™ Cranial Alternating Current Stimulation Therapy for Adults With Moderate-to-Severe Insomnia
A prospective, decentralized, individually-randomized, triple-blind* sham-controlled, superiority trial to evaluate the safety and efficacy of HALO Clarity™ device in reducing insomnia severity.
- Trial name
- NCT07659366
- Testing
- Transcranial alternating current stimulator
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Nexalin Technology
Telerehabilitation, Chair-based Yoga
The Effects of Telerehabilitation And Chair-based Yoga In The Elderly
The aim of the study is to investigate the effects of chair-based yoga with rehabilitation on quality of life is affected in elderly people.
- Conditions
- Telerehabilitation, Chair-based Yoga, Elderly People
- Trial name
- NCT05598554
- Testing
- Telerehabilitation, information
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sevval Kadriye Bakir
Multiple Sclerosis, Parkinson Disease
Intestinal Immunity in Neurologic Disease
The purpose of this study is to ascertain the functional profiles of the immune cells within the gastrointestinal tract and to determine how these cells contribute to autoimmune and neurologic diseases.
- Conditions
- Multiple Sclerosis, Parkinson Disease, REM Sleep Behavior Disorder
- Trial name
- NCT06329453
- Testing
- Colon Tissue Biopsy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yale University
Postoperative Sleep Disturbance
Dexmedetomidine Premedication for Post-anaesthesia Sleep Disturbance
The goal of this clinical trial is to learn about the effect of preoperative nasal spry with dexmedetomidine on postoperative sleep disturbance in young to middle-aged women undergoing hysteroscopy.
- Trial name
- NCT06281561
- Testing
- Normal Saline, Dexmedetomidine
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Xiamen University
Sleep Disorders, Circadian Rhythm, Craniopharyngioma
Sleep Wake and Melatonin Pattern in Craniopharyngioma
The hypothalamus is a part of the brain containing a number of nuclei with a variety of functions. It is central in the regulation of hormone secretion, sleep, and circadian functions.
- Trial name
- NCT01881854
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Breathing, Sleep Disorder
Effect of Breathing Exercise on Certain Physiological Parameters, Sleep Quality and Vitality in Elderly
Objective: To determine the effect of breathing exercises on certain physiological parameters, sleep quality and vitality in the elderly.
- Trial name
- NCT04469972
- Testing
- Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Aysun Erdal
Sleep Apnoea
Abu Dhabi Sleep Apnea (ADSA) Study
Obstructive sleep apnoea (OSA) is a common medical problem which, despite increasing awareness, remains under-diagnosed. There is a close association between OSA and obesity; 60-70% of patients diagnosed with OSA are either obese…
- Trial name
- ADSA (NCT02403141)
- Testing
- Questionnaire
- Where
- United Arab Emirates
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Imperial College London Diabetes Centre
Falls, Balance
Toileting at Night in Older Adults: Light to Maximize Balance, Minimize Insomnia
To examine the change in balance that occurs in older individuals when exposed to different colored lights at night.
- Conditions
- Falls, Balance, Insomnia, Aging
- Trial name
- NCT01350505
- Testing
- White light exposure, Dim white light exposure, Very dim white light exposure
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Heat Stress, Physiological Stress
Physiological Strain in Older Adults During a Simulated Heat Wave
A recent report showed that maintaining indoor temperature at or below 26°C safeguards older, heat vulnerable adults against potentially dangerous increases in thermal and cardiovascular strain during an extreme heat event (PMID…
- Trial name
- NCT06633302
- Testing
- Simulated multi-day heatwave exposure
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Electroencephalography, Melatonin
Sedation and Nursing Management in EEG Recording in Children
Electroencephalogram (EEG) has an important place in establishing the correct diagnosis, providing appropriate intervention, and predicting the prognosis in the long term in children.
- Conditions
- Electroencephalography, Melatonin, Chloral Hydrate, Hydroxyzine
- Trial name
- NCT05492812
- Testing
- Sedation and Nursing Management in EEG Recording in Children, Chloral Hydrate, Hydroxyzine
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Sleep Quality, Sleep Wake Disorders
Effect of L. Reuteri LM1063 on Sleep Health Improvement
Purpose: The purpose of this clinical trial is to evaluate the efficacy and safety of Limosilactobacillus reuteri LM1063 on improving sleep health in healthy adults.
- Trial name
- NCT07498712
- Testing
- Limosilactobacillus reuteri LM1063
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lactomason Co., Ltd.
Obstructive Sleep Apnea, Sleep-Disordered Breathing
Tongue Morphology and Posterior Airway Space as Predictors of Response in Patientswith Hypoglossal Nerve Stimulation Therapy
Hypoglossal nerve stimulation (HNS) plays an increasingly important role in managing patients with obstructive sleep apnea (OSA) who do not tolerate CPAP therapy and are not eligible for other alternative treatment options, such…
- Trial name
- NCT06154577
- Testing
- Ultrasonography
- Where
- 2 sites in Switzerland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital, Baselland
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