Clinical trials: Sleep Disorders
Obstructive Sleep Apnea, Hypertension
Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans
The study has been designed to assess the effect of cyclooxygenase inhibition on blood pressure, cerebral blood flow, ventilation and renal hemodynamics following chronic intermittent hypoxia exposure.
- Conditions
- Obstructive Sleep Apnea, Hypertension, Cardiovascular Diseases, Stroke
- Trial name
- NCT01280006
- Testing
- Intermittent hypoxia, Indomethacin, Celecoxib
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Aging, Age Problem
Impact of Comprehensive Dietary Counseling on Dietary Quality, Mental Health, and Quality of Life in Older Adults
As a person ages, an incidence of mental distress such as depression and anxiety increases while the quality of life decreases. Singapore's population is aging rapidly and older adults may suffer from mental distress and…
- Conditions
- Aging, Age Problem, Age-related Cognitive Decline, Age-Related Atrophy
- Trial name
- NCT03702335
- Testing
- Dietary Counselling
- Where
- 2 sites in Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Visual Impairment and Blindness (Excl Colour Blindness)
A Trial of Tai Chi Intervention for Youngsters with Visual Impairments
Investigators conducted a single-blind, randomized trial of Taijiquan exercise as compared with a control intervention consisting of wellness education and jogging for youngsters with visual impairments.
- Trial name
- NCT06450340
- Testing
- Moderate-intensity aerobic exercise refers to rhythmic and long-lasting exercise with increased heart rate, slight sweating and slight wheezing.
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Yanyun Zhang
Pediatric Intensive Care Unit, Comfort
Comfort Intervention in PICU Children
This randomized controlled trial evaluates a family-centered comfort intervention for children hospitalized in a pediatric intensive care unit.
- Conditions
- Pediatric Intensive Care Unit, Comfort, Anxiety in Children, Fear
- Trial name
- CCI-PICU (NCT07441668)
- Testing
- Intervention Family-Centered Comfort, Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Cardiac Dysfunction, Neurocognitive Disease
Football Players Health Study In Person Assessments Study
The aim of the Football Players Health Study (FPHS) is to advance the understanding of the complex and inter-related pathways that can develop into player related illness and disability.
- Conditions
- Cardiac Dysfunction, Neurocognitive Disease, Chronic Pain, Sleep Apnea
- Trial name
- IPA (NCT03866564)
- Testing
- Echocardiography, Neuropsychological Testing, Quantitative Sensory Testing
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Recovery of Function (G11.427.698.620), Athletic Performance
Effects of Magnesium L-Threonate on Sleep, Recovery, and Athletic Performance in Collegiate Athletes
This study is testing whether a special form of magnesium called magnesium L-threonate can help improve sleep quality, recovery, and physical performance in college athletes.
- Conditions
- Recovery of Function (G11.427.698.620), Athletic Performance, Heart Rate Variability (HRV)
- Trial name
- MgT-Athletes (NCT07015047)
- Testing
- Magnesium L-Threonate
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Sleep Deprivation
Impact of Sleep Deprivation on Anesthesiology Residents' Non-technical Skills
Sleep deprivation is common in anaesthesiology residents. Its effects on technical skills have been reported with controversial results.
- Trial name
- NCT02622217
- Testing
- Sleep deprivation
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Paris 5 - Rene Descartes
Postoperative Complications
The Effect of Telephone Nursing Education and Counseling Services Given to Satisfaction Level and Self-Care Strength
In the post-discharge period, it is important to follow the patients from home by telephone and to provide the necessary nursing education and counseling services, increasing the self-care powers of the patients, increasing their…
- Trial name
- NCT05487638
- Testing
- Nursing Education and Counseling Service Provided to Patients by Video Calling on the Phone
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Heat Stroke, Early Waking
Study on the Establishment of a System for Early Warning and Prognostic Evaluation of Patients With Heat Stroke
Heat stroke is a clinical syndrome with high incidence and high fatality rate in summer. Patients with liver, kidney, and brain damage are prone to secondary MODS, and the prognosis is poor due to high medical costs.
- Conditions
- Heat Stroke, Early Waking, MODS, Proteinosis
- Trial name
- NCT05155358
- Testing
- Peripheral blood test
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Schizophrenia, Psychotic Disorders
Efficacy and Mechanisms of Change of an Emotion-oriented Version of Cognitive-behavioral Therapy for Psychosis
The aim of the present single-blind randomized-controlled therapy study is to assess the efficacy of a new form of Cognitive Behavioral Therapy for delusions with a focus on emotion regulation, improvement of self-esteem and…
- Conditions
- Schizophrenia, Psychotic Disorders, Delusions, Emotions
- Trial name
- CBTd-E (NCT02787135)
- Testing
- emotion-oriented Cognitive Behavior Therapy
- Where
- 2 sites in Germany
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Insomnia Disorders
A Study to Determine the Abuse Potential of Single Oral Doses of Lemborexant Compared to Zolpidem, Suvorexant and Placebo in Healthy, Non-Dependent, Recreational Sedative Users
The primary purpose of this study is to evaluate the abuse potential of lemborexant (E2006) in comparison to placebo and 2 controls with known abuse potential (ie, zolpidem and suvorexant) with similar indications (zolpidem and…
- Trial name
- NCT03158025
- Testing
- Zolpidem tablets, Suvorexant tablets, over-encapsulated, Lemborexant tablets
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Sarcopenic Obesity
Sleep Disturbances and Biomarkers of Sarcopenic OBesity
The general objective of this study is to identify biomarkers of sleep quality, sarcopenia, insulin resistance, oxidative stress and inflammation associated with prefrailty in middle-aged and elderly obese subjects through the…
- Trial name
- SleSOB (NCT03175601)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istituto di Fisiologia Clinica CNR
COPD
Pathogenesis and Outcomes of Sleep Disordered Breathing in Chronic Obstructive Pulmonary Disease (COPD)
This research is being conducted to examine the effects of nasal insufflation of warm and humidified air through a small nasal cannula on sleep, breathing pulmonary function, and daytime exercise capability.
- Trial name
- NCT01764165
- Testing
- Oxygen, High flow of room air
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Sleep, Postpartum Depression
The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers
Insufficient and disrupted sleep are rarely addressed in expectant and new mothers, despite evidence that disturbed sleep is a modifiable risk factor for negative health outcomes for mothers and their children.
- Conditions
- Sleep, Postpartum Depression, Pregnancy Related, Insomnia
- Trial name
- NCT06737055
- Testing
- Education about behavioral strategies to improve sleep
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Sleep Disorders
Sleep Disturbances in Hospitalized Children
Background Sleep disturbances are prevalent in hospitalized adult patients manifested as reduced sleep time and sleep efficiency as well as increased awakenings. Insomnia is the most frequent sleep disturbance.
- Trial name
- NCT00749814
- Testing
- Melatonin
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Sleep Disorders
Validation of Home Sleep Testing (WP) Compared to an Overnight Sleep Testing in the Sleep Laboratory
Obstructive sleep apnea syndrome (OSAS) is considered to be a major public health problem. The prevalence of OSAS is estimated at 2% and 4% for adult women and men respectively, most of whom are undiagnosed and untreated.
- Trial name
- NCT01570738
- Where
- Israel
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Itamar-Medical, Israel
Depression
Promoting Sleep and Healthy Aging Research Study (PRO-SHARE)
The objective of this study is to evaluate the ability of a behavioral intervention, cognitive behavioral therapy for sleep quality (CBT-SQ) to reduce sleep complaints, depression recurrence, and cellular and genomic markers of…
- Trial name
- PRO-SHARE (NCT01641263)
- Testing
- Sleep Education Therapy, Cognitve Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Obstructive Sleep Apnea
Skiin-PSG Sleep Apnea
The goal of this observational study is to develop new algorithms to detect apnea and/or hypopnea to provide additional insights to Skiin users and to their circle of care to validate and/or improve the current algorithms of the…
- Trial name
- NCT06247878
- Testing
- Skiin underwear chest band
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Myant Medical Corp.
Obstructive Sleep Apnea
Bioavailability, Bioequivalence and Tolerability of IHL-42X Compared to the Reference Drugs
The goal of this randomised four-period cross-over Phase I study is to assess bioavailability, bioequivalence and tolerability of IHL-42X compared to the reference drugs in healthy volunteers.
- Trial name
- NCT05857384
- Testing
- IHL42X, Acetazolamide 250 MG, Dronabinol 2.5 MG
- Where
- 4 sites in Australia
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Incannex Healthcare Ltd
Sleep, Insomnia
Impact of Sleep Workshops in College Students
The purpose of this pilot study is to assess the impact of sleep workshops on sleep, mood, anxiety and well-being measures in a sample of college students.
- Conditions
- Sleep, Insomnia, Sleep Deprivation
- Trial name
- NCT02665247
- Testing
- C-SIP, Dream discussion
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
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