Clinical trials: Sleep Hypopnea
Obstructive Sleep Apnea
Efficacy of Stellate Ganglion Block in Obstructive Sleep Apnea
The goal of this clinical trial is to test the efficacy of stellate ganglion block in Obstructive Sleep Apnea. The main question it aims to answer are: Can stellate ganglion block improve Obstructive Sleep Apnea? Patients were…
- Trial name
- OSA (NCT06265792)
- Testing
- routine rehabilitation treatment, Stellate ganglion block
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Zeng Changhao
Complex Sleep Apnea, CPAP Induced Central Sleep Apnea
Bilevel Versus Servoventilation in Complex Sleep Apnea
Randomized trial to evaluate the performance of Bilevel vs. Servoventilation in patients with complex sleep apnea during continuous positive airway pressure (CPAP) treatment.
- Trial name
- CSA-FKKG (NCT01609244)
- Testing
- Bilevel therapy (somnovent ST 22, Weinmann, Hamburg, Germany), servoventilation (Somnovent CR, Weinmann, Hamburg, Germany)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Krankenhaus Kloster Grafschaft
Obstructive Sleep Apnea
Reducing Obstructive Sleep Apnea After Hypoglossal Nerve Stimulation Through Mandibular Advancement
The purpose of this study is to evaluate the effectiveness, feasibility, and safety of mandibular advancement devices (MAD) for treating severe obstructive sleep apnea (OSA) in patients who are CPAP intolerant and have failed…
- Trial name
- ROHMA (NCT07132307)
- Testing
- Mandibular advancement device (MAD)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Washington University School of Medicine
Sleep-Disordered Breathing, Sleep Architecture
Screening of OSA in Hospitalized Stroke Patients Using BSP
Obstructive sleep apnea (OSA) is prevalent in patients with stroke and has a negative effect on outcomes by predisposing them to recurrent stroke, increasing mortality, and so forth.
- Conditions
- Sleep-Disordered Breathing, Sleep Architecture, Stroke, Acute
- Trial name
- NCT05466864
- Testing
- Belun Sleep platform
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Sleeping Disorders
Effects of Sesamin on Sleep Quality and Antioxidative Status
Sesame recognized as a common healthy food. Sesamin is extracted from sesame and has high antioxidant capacity which is commonly added in functional foods.
- Trial name
- NCT05678439
- Testing
- sesame extract
- Where
- 2 sites in Taiwan
- Volunteers
- 33 people
- Sponsor
- Taipei Medical University
Apnea Syndrome, Apnea, Obstructive
Effect of Hypnosis on Adherence to Continuous Positive Airway Pressure.
The prevalence of sleep-disordered breathing is high, with an apnea-hypopnea index of over 15 per hour found in 49.7% of men and 23.4% of women in the general population (1).
- Trial name
- HypnOSA (NCT06397365)
- Testing
- medical hypnosis
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Solelhac Geoffroy
Acute Myocardial Infarction, Sleep Apnea
ASV for Sleep Apnea After Myocardial Infarction
The aim of this randomized controlled trial is to test the effect of 12 weeks Adaptive Servo-Ventilation (ASV) therapy (additionally to optimal medical management of myocardial infarction) on myocardial salvage (MSI=myocardial…
- Trial name
- TEAM-ASV-I (NCT02093377)
- Testing
- Adaptive servo-ventilation
- Where
- 5 sites in Germany
- Volunteers
- 79 people
- Sponsor
- University Hospital Regensburg
Snoring, Sleep Disturbances
Evaluating Sleep Quality With Emerging Technologies
To investigate the sleep quality of the adult orthodontic patient population at the Case Western Reserve University School of Dental Medicine using the NOSE Questionnaire, STOP-BANG Questionnaire, SleepCycle app, and Belun Ring.
- Conditions
- Snoring, Sleep Disturbances, Hypoxia, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT06900530
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Obstructive Sleep Apnea (OSA)
Biomarkers for Obstructive Sleep Apnea
The purpose of the study is to: recruit subjects with untreated sleep apnea; assess overnight changes in their blood and urine chemicals review the overnight changes in blood and urine chemicals after they have been treated for…
- Trial name
- BOSA (NCT00834509)
- Testing
- CPAP
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Acute Ischemic Stroke, Sleep Apnea
Continuous Positive Airway Pressure for the Treatment of Stroke
New stroke therapies are needed. This study seeks to provide the preliminary data needed to plan a future study that will evaluate the efficacy of using continuous positive airway pressure (CPAP) to treat stroke patients who have…
- Trial name
- NCT00368628
- Testing
- continuous positive airway pressure
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Yale University
Arterial Hypertension
"Escape" Phenomenon of the Antihypertensive Therapy Efficacy
A little attention is paid to the AHT efficacy escaping problem, which can be explained by the AHT correction simplicity and rapid achievement of the target BP level.
- Trial name
- ESCAPE (NCT05436730)
- Testing
- Ambulatory blood pressure measurement device, Sphygmocor, VaSera-VS
- Where
- Russia
- Volunteers
- 165 people
- Sponsor
- Federal State Budgetary Institution NATIONAL MEDICAL RESEARCH CENTRE OF CARDIOLOGY NAMED AFTER ACADE
Obstructive Sleep Apnea
Continuous Positive Airway Pressure (CPAP) Promotion And Prognosis - the Army Sleep Apnea Program (ASAP)
The purpose of this study is to assess the efficacy of Eszopiclone in improving short and intermediate-term compliance with continuous positive airway pressure (CPAP) in patients newly diagnosed with obstructive sleep apnea (OSA).
- Trial name
- CPAPASAP (NCT00612157)
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Walter Reed Army Medical Center
Periodic Breathing
Different Loop Gain Phenotypes in Patients With Chronic Systolic Heart Failure and Periodic Breathing
Central sleep apnoea (CSA) is common in patients with chronic systolic heart failure (HFrEF). Various trials have shown a prevalence of 21 - 37% in this group of people.
- Trial name
- NCT03532412
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Obstructive Sleep Apnea
Safety Monitoring for a Novel 3D Printed Mandibular Advancement Device
The purpose of this study is to evaluate the safety profile of the novel oral appliance (OA )device and to assess patient comfort of the novel OA device.
- Trial name
- NCT05018234
- Testing
- Noval Oral Appliance
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Sleep Apnea Syndromes
Sodium Channel Splicing in Obstructive Sleep Apnea (SOCS-OSA)
This study is designed to test whether SCN5A mRNA processing is altered in OSA patients, which may contribute to their increased arrhythmic risk, and whether processing of SCN5A mRNA is modulated by CPAP treatment.
- Trial name
- NCT02725632
- Testing
- CPAP
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Rhode Island Hospital
Obstructive Sleep Apnea
Whitsundays (Nasal) Singapore External Clinical Study 1 Protocol
Each Whitsunday mask or AirFit N30i Quiet mask is worn for 7 nights. The overall purpose of this study is to evaluate the performance of the Whitsundays nasal mask system (a prototype mask) compared to the ResMed AirFit N30i…
- Trial name
- NCT05255744
- Testing
- Positive Airway Pressure (PAP) Therapy
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ResMed
Obstructive Sleep Apnea of Child
Endothelial Dysfunction and Oxidative Stress in Children With Sleep Disordered Breathing.
Sleep disordered breathing (SDB) is a common disease in both adults and children and is caused by the obstruction of the upper airway during sleep.
- Trial name
- NCT02247167
- Testing
- adenotonsillectomy
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Roma La Sapienza
OSA, SCI/D
Novel by Upper Airway Respiratory Muscle Training to Treat OSA in Chronic SCI
It is estimated that spinal cord injury (SCI) affects approximately 12,000 new individuals every year in the United States, with the majority are cervical and/or upper thoracic injuries.
- Conditions
- OSA, SCI/D, Upper Airway Exercise
- Trial name
- NOURMT-OSA (NCT03664765)
- Testing
- UA and RMT
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea, Sleep Apnea
Recording of Multiple Nights Using a New Contactless Device (Sleepiz One Connect) in Obstructive Sleep Apnea
The need for multiple night testing is well recognized in sleep medicine because of a considerable and relevant night-to-night variability.
- Conditions
- Obstructive Sleep Apnea, Sleep Apnea, Respiratory Tract Disease, Respiration Disorder
- Trial name
- NCT05134402
- Testing
- Sleepiz One Connect
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Samuel Tschopp
Sleepiness, SARS-CoV2 Infection
Obstructive Sleep Apnoea Post Covid 19: Role of the Upper Airway Microbiome
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causing coronavirus disease, Covid-19, has spread rapidly across the globe since its emergence in January 2020.
- Conditions
- Sleepiness, SARS-CoV2 Infection, Fatigue Syndrome, Chronic, Snoring
- Trial name
- NCT05116657
- Testing
- Nasal Lavage and Oral Wash
- Volunteers
- 50 people
- Sponsor
- Royal College of Surgeons, Ireland
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