Clinical trials: Sleep Hypopnea
Obstructive Sleep Apnea
High Flow Nasal Cannula for Obstructive Sleep Apnea
This study compare the efficacy of high flow nasal cannula with nasal continuous positive airway pressure. All of participants will be randomized to receive one night high flow nasal cannula therapy and another night for nasal…
- Trial name
- NCT03843372
- Testing
- High flow nasal cannula
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- Chung-Chieh, Yu
Obstructive Sleep Apnea
The Evaluation of a Full Face Mask Seal for the Treatment of Obstructive Sleep Apnea
The investigation is a prospective, randomized, single blinded, crossover study. The investigation is designed to evaluate the performance, comfort and ease of use of the F\&P Trial Full Face Mask Seal amongst Obstructive Sleep…
- Trial name
- NCT03230877
- Testing
- Toffee full face mask with 'Improved Seal', Toffee full face mask with 'Normal Seal'
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Sleep Apnea : Diagnosis and Monitoring
This prospective study aims to evaluate a new medical screening method to detect and discriminate sleep apnea-hypopnea events. A new device called ApneaBand will be tested to propose a new screening method facilitating the…
- Trial name
- ApneaBand (NCT03571477)
- Testing
- ApneaBand
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea
Effectiveness of Stellate Ganglion Block for the Treatment of Obstructive Sleep Apnea
The goal of this clinical trial is to test the efficacy of stellate ganglion block in Obstructive Sleep Apnea. The main question it aims to answer are: Can stellate ganglion block improve Obstructive Sleep Apnea? Patients were…
- Trial name
- NCT06319612
- Testing
- routine rehabilitation treatment, Stellate ganglion block, Lidocaine Hydrochloride
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Obstructive Sleep Apnea
Phototherapy for Non-responders to Oral Appliance Therapy for Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a medical condition where a person has great difficulty with breathing, or stops breathing all together, while asleep.
- Trial name
- NCT06960200
- Testing
- Phototherapy
- Where
- Canada
- Volunteers
- 528 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Obstructive Sleep Apnea
Assessing the Symptoms of Obstructive Sleep Apnea
The purpose of this study is to investigate the correlation between health outcomes associated with the severity of obstructive sleep apnea (OSA) symptomatology, the findings will guide the design of interventional studies.
- Trial name
- OSA (NCT01481636)
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- Bangor University
Excessive Daytime Sleepiness, Narcolepsy
Extension Study of the Safety and Efficacy of Armodafinil in the Treatment of Patients With Excessive Sleepiness
A 12 Month, Open-Label, Flexible Dosage Extension Study of the Safety and Efficacy of Armodafinil (CEP-10953) in the Treatment of Patients with Excessive Sleepiness Associated with Narcolepsy, Obstructive Sleep Apnea/Hypopnea…
- Conditions
- Excessive Daytime Sleepiness, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, Chronic Shift Work Sleep Disorder
- Trial name
- NCT00228553
- Testing
- Armodafinil 100 to 250 mg/day
- Where
- 100 sites in United States, Australia and 5 more
- Volunteers
- 743 people
- Sponsor
- Cephalon
Altitude Hypoxia
Effect of Acetazolamide on Sleep Disordered Breathing in Lowlanders Older Than 40 Years at Altitude
Randomized, placebo controlled trial evaluating the effect of acetazolamide on sleep disordered breathing in lowlanders older than 40 years travelling from 760 m to 3'100 m.
- Trial name
- NCT03536507
- Testing
- ACETAZOLAMIDE oral capsule
- Where
- Kyrgyzstan
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Obstructive Sleep Apnea
Measuring Effectiveness in Sleep Apnea Surgery
The goal of this research is to improve our understanding of the effectiveness of surgical OSA treatment by evaluating its impact on these health-related and functional outcomes and comparing these effects to the changes in…
- Trial name
- NCT00518128
- Testing
- Surgical OSA treatment, Positive Airway Pressure Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Sleep Apnea
A Study of VI-0521 for the Treatment of Obstructive Sleep Apnea / Hypopnea Syndrome in Obese Adults
The primary objectives of this study are to evaluate the safety and efficacy of VI-0521 compared to placebo in the treatment of obese adults with obstructive sleep apnea (OSA) and to assess the relative contributions of weight…
- Trial name
- NCT00745251
- Testing
- VI-0521
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- VIVUS LLC
Sleep Apnea, Obstructive
The Phenotyping and Genotyping of Taiwanese Patients With Obstructive Sleep Apnea
The growing evidence showed that the OSA is a heritable complex genetic disease where the genetic basis contributed the development of OSA and its sequel. The phenotyping of OSA include high level and intermediate level.
- Trial name
- NCT02038751
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- National Taiwan University Hospital
Obesity, Obstructive Sleep Apnea
Severe Obesity Outcome Network Cohort (SOON)
The main objective of the study is to identify the determinant of sleep characteristics of obese patients attempting a tertiary clinical center for obesity management, including bariatric surgery.
- Conditions
- Obesity, Obstructive Sleep Apnea, Sleep
- Trial name
- SOON (NCT02264431)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea
Ambulatory Blood Pressure Control and Cognition in Patients With Obstructive Sleep Apnea (AMPLE)
To compare the blood pressure control and cognitive responses of three groups of patients: those diagnosed with Obstructive Sleep Apnea (OSA) and treated with Continuous Positive Airway Pressure (CPAP) for at least six months…
- Trial name
- AMPLE (NCT06463002)
- Testing
- Ambulatory blood pressure monitoring and Montreal Cognitive Assessment
- Where
- Singapore
- Volunteers
- 150 people
- Sponsor
- National University Hospital, Singapore
OSA
Parallel-Arm Study to Compare AD109 to Placebo With Patients With OSA (SynAIRgy Study)
This is a Phase 3 Randomized Double-Blind Placebo-Controlled 6-month Parallel-Arm Study to Compare a Fixed Dose Combination of AD109 to Placebo in Obstructive Sleep Apnea.
- Trial name
- NCT05813275
- Testing
- AD109
- Where
- 73 sites in United States, Canada
- Volunteers
- 646 people
- Sponsor
- Apnimed
Obstructive Sleep Apnea
Validation and Reproducibility of the Six-minute Step Test in Individuals With Obstructive Sleep Apnea Treated With CPAP
Introduction: The Obstructive Sleep Apnea (OSA) is characterized by obstructed superior airway during sleeping period promoting intermittent hypoxia-reoxygenation events.
- Trial name
- NCT03334331
- Testing
- Six-minute step test, Six-minute walk test
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Universidade Federal de Pernambuco
Decrease of Inflammation of Adipose Tissue, Sleep Apnea Syndrome
Inflammation and Oxidative Stress of Adipose Tissue in Sleep Apnea Syndrome
The main objective of this study is to evaluate the decrease of inflammation of adipose tissue in obese and non-obese patients having a sleep apnea syndrome and treated or not by continuous positive airway pressure (cPAP).
- Trial name
- ADISAS (NCT01196845)
- Testing
- cPAP
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea
Correlation Between Serum Uric Acid and Pulmonary Hypertension in Obstructive Sleep Apnea Syndrome
This study aimed to correlate serum uric acid levels and PAH in OSAHS patients.
- Trial name
- NCT05967754
- Testing
- polysomnography
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Post Traumatic Stress Disorder, Obstructive Sleep Apnea
OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit
Substance use disorder (SUD) and posttraumatic stress disorder (PTSD) frequently co-occur and having both disorders is associated with greater psychological and functional impairment than having either disorder alone.
- Conditions
- Post Traumatic Stress Disorder, Obstructive Sleep Apnea, Substance Use Disorder, Residential Treatment Program
- Trial name
- NCT05156112
- Testing
- Positive Airway Pressure Device
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- VA Office of Research and Development
Sleep Apnea
Comparison Of The Berlin Questionnaire To The Portland Sleep Quiz
This trial is enrolling patients who are already being seen at OHSU sleep disorder center or have been referred for clinical reasons by their physician to the OHSU sleep disorder center and are going to have a sleep study that…
- Trial name
- NCT01269073
- Where
- United States
- Sponsor
- Akram Khan
Sleep Apnea Syndrome, Obstructive
Treatment Failure of Continuous Positive Airway Pressure (CPAP) in Patients With Obstructive Sleep Apnea Syndrome (OSA): A Trial Comparing Polysomnography and the Sunrise Device to Drive Treatment-Adjustment Decisions.
The goal of this clinical trial is to determine whether treatment-adjustment decisions based on one night of home monitoring with the Sunrise device are comparable to decisions based on one night of in-laboratory polysomnography…
- Trial name
- SUNCPAP (NCT07530302)
- Testing
- Sunrise
- Where
- France
- Volunteers
- 105 people
- Sponsor
- University Hospital, Grenoble
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