Clinical trials: Sleep Hypopnea
Obesity Hypoventilation Syndrome, Obesity
The Effect of Obesity Hypoventilation Syndrome on Exercise Capacity, Peripheral Muscle Strength, and Quality of Life in Obese Individuals
Obesity Hypoventilation Syndrome(OHS) is a disease characterized by daytime hypercapnia and sleep-disordered breathing without other causes of hypoventilation in individuals with a body mass index above 30 kg/m2.
- Conditions
- Obesity Hypoventilation Syndrome, Obesity, Hypoventilation, Respiration Disorders
- Trial name
- NCT06142513
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University
Insomnia, Obstructive Sleep Apnea
The Impact of CBT-i on CPAP Therapy Use and Drop Outs in OSAS Patients With Insomnia.
Patients follow the fully standard sleep test according to the normal procedure. This means that they undergo a polysomnography and fill in a questionnaire.
- Conditions
- Insomnia, Obstructive Sleep Apnea, Cognitive Behavioral Therapy, Continuous Positive Airway Pressure
- Trial name
- NCT04306835
- Testing
- Cognitive behavioural therapy for insomnia
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitair Ziekenhuis Brussel
Obstructive Sleep Apnea, Polysomnography
Screening Moderate to Severe Obstructive Sleep Apnea With Wearable Device
The goal of this study is to find the best method to use Wellue O2 ring to screen for moderate to severe obstructive sleep apnea.
- Conditions
- Obstructive Sleep Apnea, Polysomnography, Pulse Oximetry
- Trial name
- NCT06454318
- Testing
- Wellue O2 ring
- Where
- Thailand
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Thammasat University Hospital
Sleep Disordered Breathing, Obstructive Sleep Apnea
The Evaluation of a Nasal Mask for the Treatment of Obstructive Sleep Apnea
This investigation is designed to evaluate the performance as well as the patients overall acceptance of the mask.
- Trial name
- NCT03156413
- Testing
- F&P nasal mask
- Where
- New Zealand
- Volunteers
- 12 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea (OSA)
Pilot Study of the Comparison of the Upper Airway Dynamics of Oronasal vs Nasal Masks With PAP Treatment
Our group has recently found that the choice of positive airway pressure mask can significantly affect the pressure required to adequately treat sleep disordered breathing.
- Trial name
- Mask_MRI (NCT01939938)
- Testing
- Nasal and Oronasal PAP Mask
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Obstructive Sleep Apnea, PTSD
Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD
Approximately 20 million Americans suffer from Obstructive Sleep Apnea (OSA) creating risks for major health problems, including dementia, heart attack, and stroke.
- Conditions
- Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
- Trial name
- NCT02641496
- Testing
- CBT-OSA, Sleep Education
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Dilated Cardiomyopathy
BiPAP for Cardiomyopathy With Central Sleep Apnea
We investigated whether treatment of central sleep apnea-hypopnea with bilevel positive airway pressure (BiPAP) in patients with idiopathic dilated cardiomyopathy (IDCM) would improve LV function.
- Trial name
- NCT00282789
- Testing
- bilevel positive airway pressure, bilevel positive airway pressure (Device)
- Where
- Japan
- Sponsor
- Nagoya University
Heart Failure (HF)
SchlaHF-XT-Register. Sleep Disordered Breathing in Heart Failure Register
The SchlaHF XT Registry is a longitudinal study of patients with heart failure (HF). The study aims to understand the importance of diagnosis and treatment of sleep disordered breathing (SDB) on HF with the following questions…
- Trial name
- NCT02301689
- Where
- Germany
- Volunteers
- 4,749 people
- Sponsor
- ResMed
Obstructive Sleep Apnea
BASET Scoring: A Novel Simple Biometric Score and Potential Tool for Diagnosis and Grading of Obstructive Sleep Apnea Syndrome (OSAS) Patients
this study aims to assess the validity of BASET scoring as a new potential tool for diagnosis and grading the severity of OSAS patients and as screening of the risk factors of OSAS.
- Trial name
- BASET (NCT05511974)
- Testing
- BASET score
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Mansoura University
Obstructive Sleep Apnea (OSA)
Continous Positive Airway Pressure (CPAP) Compliance Study
Does an internet based text or email interaction and education improve CPAP compliance for patients with Obstructive sleep apnea (OSA) and reduce nursing intervention.
- Trial name
- ICAN (NCT01642160)
- Testing
- additional educational material, Standard of care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Obstructive Sleep Apnea
Predictive Analytics and Peer-Driven Intervention for Guideline-based Care for Sleep Apnea
Obstructive sleep apnea (OSA) is a prevalent condition that affects 7 to 12% of the US population and is characterized by repetitive collapse of the upper airway during sleep.
- Trial name
- NCT03345524
- Testing
- Peer-Buddy System, Usual Care
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- University of Arizona
Sleep Disorder
A Prospective Study to Evaluate the WP in Comparison to PSG in Patients Suspected of Sleep Disorders
The current study is a prospective blinded study to collect data regarding the performance of the WP device in detecting sleep disorders.
- Trial name
- NCT06093633
- Where
- 3 sites in United States, Israel
- Volunteers
- 600 people
- Sponsor
- Itamar-Medical, Israel
Obstructive Sleep Apnea, Cardiovascular (CV) Risk
Prospective Evaluation of New Metrics to Assess Cardiovascular Remodeling in Obstructive Sleep Apnea
The goal of this prospective study is to gain insight into the endophenotypic variation in OSA, with a focus on the underlying pathophysiological traits and the cardiovascular alterations associated with the condition.
- Trial name
- CARDOSA (NCT07427589)
- Testing
- Continuous positive airway pressure, Mandibular advancement device, Hypoglossal nerve stimulation
- Where
- Belgium
- Volunteers
- 270 people
- Sponsor
- University Hospital, Antwerp
Insomnia, Apnea
Novel Treatment of Comorbid Insomnia and Sleep Apnea in Older Veterans
The purpose of this study is to determine whether a novel intervention combining cognitive behavioral therapy for insomnia plus a positive airway pressure (PAP) behavioral adherence program provided by allied health personnel for…
- Trial name
- NCT02027558
- Testing
- Insomnia treatment & PAP adherence, General sleep education
- Where
- 2 sites in United States
- Volunteers
- 125 people
- Sponsor
- VA Office of Research and Development
Sleep Disorder, Body Fat Distribution
Relationship Between Normal-weight Central Obesity and Obstructive Sleep Apnea
Comparison of the prevalence of obstructive sleep apnea (OSA), measured by polysomnography in normal weight patients with central obesity by body mass index (BMI) and waist hip ratio (WHR), with normal weight patients without…
- Trial name
- NCT04061226
- Testing
- Overnight polysomnography
- Where
- Czechia
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Obstructive Sleep Apnea
Regulation of Vascular Thrombosis in Sleep Apnea
Sleep Apnea is a prevalent condition that has been increasingly diagnosed in the adult population and is now considered an independent risk factor for the development of cardiovascular disease.
- Trial name
- NCT00859690
- Volunteers
- 14 people
- Sponsor
- Weill Medical College of Cornell University
Hypopnea Syndrome, Apnea, Obstructive Sleep
Impact of Continuous Positive Airway Pressure Therapy on Bilateral Local Hippocampal Gray Matter Volume in Elderly Patients With Obstructive Sleep Apnea - Study BBBSAS
This study evaluates whether treating severe obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) for approximately 6 months modifies local hippocampal and frontal cortex gray matter volume and…
- Trial name
- BBBSAS (NCT07882433)
- Testing
- Continuous Positive Airway Pressure (CPAP) therapy, Multimodal brain MRI with Gadolinium injection
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Hypoxia, OSA
MEA DPA Hypoxic Event Reductions
The goal of the study is to compare deoxygenation events during anesthesia induction and mask ventilation when using standard oral pharyngeal airways or the novel distal pharyngeal airway.
- Conditions
- Hypoxia, OSA, Obesity
- Trial name
- NCT07572500
- Testing
- DPA, OPA
- Sponsor
- Stanford University
Epilepsy, Sleep Apnea
Effects of Treating Obstructive Sleep Apnea in Epilepsy
The purpose of this trial is to work out design issues prior to conducting a definitive phase 3 trial to determine whether treating sleep-related breathing disorders in people with epilepsy results in improvement in seizure…
- Conditions
- Epilepsy, Sleep Apnea, Obstructive Sleep Apnea
- Trial name
- NCT00047463
- Testing
- continuous positive airway pressure (CPAP)
- Where
- 4 sites in United States
- Volunteers
- 68 people
- Sponsor
- Vanderbilt University
Obstructive Sleep Apnea of Adult
ThErapy Adherence Management in Veterans
The study is a prospective, randomized, controlled trial studying adherence to positive airway pressure therapy in a population referred to the VA system for the treatment of sleep disordered breathing.
- Trial name
- NCT03243487
- Testing
- structured adherence management program, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Florida
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