Clinical trials: Sleep Problems, open to volunteers
Overweight and Obesity, Cardiovascular Diseases
Study Consortium for Evaluation of RNPC Program in Obese and Overweight Patients (SCOOP-RNPC)
The investigators hypothesize that weight loss obtained with the French RNPC weight reduction program is beneficial for the general health of overweight/obese patients in the medium term.
- Conditions
- Overweight and Obesity, Cardiovascular Diseases, Metabolic Disease, Diabete Type 2
- Trial name
- SCOOP-RNPC (NCT05857319)
- Testing
- Nutritional Psycho-Behavioral Reeducation Program
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Groupe Éthique et Santé
Sleep
Saffron Extract Supplementation and Sleep Quality in Middle-Aged Adults
This randomized, triple-blind, placebo-controlled clinical trial aims to evaluate the effects of daily saffron extract supplementation (30 mg/day) for six weeks on objective and subjective sleep quality in middle-aged adults with…
- Trial name
- SAFFRON-SLEEP (NCT07497698)
- Testing
- Saffron Extract
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Intensive Care Unit, Critical Care
Effects of Nonpharmacological Interventions in Sleep Quality, Anxiety, and Delirium for Patients of Adult Intensive Care Units
This study will investigate the effect of nonpharmacological intervention in sleep quality, anxiety and delirium among adult ICU patients.
- Conditions
- Intensive Care Unit, Critical Care, Sleep Quality, Anxiety
- Trial name
- Sleep (NCT06774599)
- Testing
- music combined with lavender essential oil group
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Chiayi Christian Hospital
Insomnia Disorder
Virtual Reality Relaxation for Insomnia
The goal of this clinical trial is to evaluate the feasibility, acceptability, and preliminary effects of a virtual reality (VR) relaxation intervention among adults aged 25 to 50 with insomnia disorder.
- Trial name
- NCT07630532
- Testing
- Virtual reality relaxation intervention
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Metabolic Syndrome, Insulin Resistance
Asprosin and miRNA Expression in Young Women With Metabolic Syndrome
Metabolic syndrome is a major risk factor for cardiovascular disease and type 2 diabetes, and its prevalence in young adults is increasing. Early identification of individuals at risk may improve prevention strategies.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Obesity, Abdominal, Dyslipidemias
- Trial name
- ASPRO-MetS (NCT07917364)
- Testing
- Biomarker panel (asprosin, microRNA, BDNF, cortisol), Clinical and questionnaire assessment
- Where
- Poland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences in Nowy Targ
Obstructive Sleep Apnea, Sleepiness
Obstructive Sleep Apnea Therapeutic Intervention for REsiDual Sleepiness
Obstructive sleep apnea (OSA) is a sleep disorder that is commonly treated using positive airway pressure, yet 50% of patients still experience residual sleepiness after successful therapy.
- Trial name
- STIL TIRED (NCT06698809)
- Testing
- Active tPBM
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Obstructive Sleep Apnea, Gastric Cancer (GC)
Prolonged Extubation in Gastric Cancer With OSA
This study aims to investigate the effect of prolonged tracheal intubation removal on the incidenceof postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.
- Trial name
- Gastric Cancer (NCT07362706)
- Testing
- Prolonging the duration of postoperative endotracheal intubation before extubation.
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Qilu Hospital of Shandong University
Obstructive Sleep Apnea of Child, Sleep-Disordered Breathing
Comparison of Two Reeducation Methods in Children With Persistent Sleep Apnea, a Randomized Controlled Trial
Myofunctional therapy has been shown to be effectively reduce symptoms of paediatric obstructive sleep apnea, usually performed after adenotonsillectomy.
- Conditions
- Obstructive Sleep Apnea of Child, Sleep-Disordered Breathing, Adenotonsillar Hypertrophy
- Trial name
- PERSIST-B-RCT (NCT06634264)
- Testing
- Soft Oral Appliance
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Université de Montréal
Cancer, Insomnia
A Prospective Multi-Center Real-World Study of Ciwujia Capsules in the Treatment of Cancer-Related Insomnia
Cancer poses a severe threat to human physical and mental health as well as survival. High diagnostic rates of cancer and various treatments can significantly impact patients' sleep quality, leading to diverse sleep disorders.
- Conditions
- Cancer, Insomnia, Cancer Related Insomnia
- Trial name
- NCT07050121
- Testing
- Ciwujia capsules
- Volunteers
- 3,000 people
- Sponsor
- Shanghai Municipal Hospital of Traditional Chinese Medicine
Postoperative Sleep Disturbance, Breast Cancer Surgery
Lemborexant on Perioperative Sleep Quality in Patients Undergoing Breast Cancer Surgery
Breast cancer is one of the most common malignancies among women worldwide, and surgery remains its primary treatment modality. Perioperative sleep disturbance, anxiety, depression, and acute postoperative pain are common…
- Trial name
- NCT07918300
- Testing
- Lemborexant 5 mg
- Volunteers
- 106 people
- Sponsor
- Beijing Tiantan Hospital
Adolescent, Scoliosis
Sleep Quality in Adolescents With Idiopathic Scoliosis
This controlled cross-sectional observational study aims to compare sleep quality between adolescents with idiopathic scoliosis and age- and sex-similar healthy controls.
- Conditions
- Adolescent, Scoliosis, Adolescent Idiopathic Scoliosis (AIS)
- Trial name
- AIS-SLEEP (NCT07767591)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Physical Therapy, Resistance Exercise
Resistance Exercise and Sleep Quality by Chronotype
This study examines whether doing moderate resistance exercises in the morning can improve sleep quality and well-being in young adults.
- Conditions
- Physical Therapy, Resistance Exercise, Sleep Disturbances, Sleep Quality
- Trial name
- TRE-SLEEP (NCT07234812)
- Testing
- Moderate-Intensity Resistance Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Medipol University
Sleep and Circadian Problems
Perioperative Sleep Recovery Trajectories in Patients of Different Sexes Undergoing Laparoscopic Cholecystectomy
This is an observational clinical study. It does not give new treatments to participants. Researchers want to learn how sleep gets better or worse after laparoscopic gallbladder removal surgery.
- Trial name
- NCT07863804
- Testing
- No study intervention
- Volunteers
- 58 people
- Sponsor
- Li Juan
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose…
- Conditions
- Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension
- Trial name
- POPS or POP02 (NCT04278404)
- Testing
- The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Loneliness, Insomnia
The WISE Study (WhatsApp Intervention for Sleep in the Elderly)
Sleep hygiene education is an educational effort to teach healthy sleep habits and behaviors to improve sleep quality, duration, and regularity naturally without the use of medication; however, this approach has not been…
- Trial name
- WISE (NCT07751458)
- Testing
- Nurse-led WiSE intervention group
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Halu Oleo University
Insomnia, Depression
Acute Psychological Sleep Stabilisation for Patients Hospitalised With Depression
Disturbed sleep occurs in almost all patients in psychiatric inpatient care, and although it is well known that comorbid sleep disorders in depression often persist after treatment of depression and also increase the risk of new…
- Trial name
- NCT06145555
- Testing
- Acute psychological sleep stabilization, Sleep hygiene education
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Primary Insomnia
Acupoint Selection Based on Meridian Theory in Primary Insomnia of Liver Depression and Spleen Deficiency Type
The classical literature combined with modern medicine to select acupoints, in order to intervene in the autonomic nerve function of the superior cervical sympathetic ganglion as an opportunity, put forward the meridian acupoints…
- Trial name
- NCT06782815
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Chuanlong Zhou
Insomnia, Depression
The Sleep Course: An Online Sleep Intervention for Adults With Self-reported Sleep Difficulties
This study evaluates an internet-delivered cognitive behavioural therapy for insomnia (ICBTi) intervention, known as the Sleep Course, within a routine online therapy clinic (the Online Therapy Unit).
- Conditions
- Insomnia, Depression, Anxiety
- Trial name
- NCT06745349
- Testing
- Sleep Course
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Regina
Hereditary Hemorrhagic Telangiectasia (HHT), Obstructive Sleep Apnea (OSA)
Prevalence of Obstructive Sleep Apnea in HHT and HHT-specific Challenges in OSA-therapy - a Retrospective Cohort Study
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder (prevalence approx. 1:5,000-1:8,000) characterized by recurrent epistaxis, mucocutaneous telangiectasias and visceral vascular malformations.
- Trial name
- NCT07886632
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Essen
Sleep Apnea, Obstructive, Larynx
Accuracy of the Sensory Test Using the Laryngopharyngeal Endoscopic Esthesiometer in Obstructive Sleep Apnea
This is a prospective double blinded randomized crossover controlled trial aiming at validating the measurement of laryngopharyngeal mechanosensitivity in patients with suspected OSA using a recently developed laryngopharyngeal…
- Conditions
- Sleep Apnea, Obstructive, Larynx, Sensory Disorder
- Trial name
- NCT03109171
- Testing
- Laryngopharyngeal sensory test
- Where
- 2 sites in Colombia
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Fundación Neumologica Colombiana
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