Clinical trials: Sleep Wake Disorders
Sleep Disorder, Blindness
Melatonin Studies of Totally Blind Children
The purpose of this study is to learn more about abnormal body rhythms in blind boys and girls that keep them from falling asleep at bed-time or cause them difficulty staying alert during the day.
- Trial name
- NCT00795236
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Chronic Obstructive Pulmonary Disease, Sleep Related Hypoventilation
Health Outcomes With CPAP or NIV in Patients With COPD and a Sleep Related Breathing Disorder
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease affecting an estimated 1 in 10 Canadians. Symptoms include persistent shortness of breath, cough and sputum production.
- Conditions
- Chronic Obstructive Pulmonary Disease, Sleep Related Hypoventilation, Obstructive Sleep Apnea, Hypoventilation
- Trial name
- NCT05623709
- Testing
- Positive airway pressure with continuous positive airway pressure or noninvasive ventilation
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Insomnia
Effectiveness of a Guided Self-help Intervention for Improving Sleep in University Students
This randomized controlled trials aims to assess the effectiveness of an online guided self-help intervention ('i-Sleep \& BioClock') based on CBTi principles for university students' sleep problems.
- Trial name
- NCT06023693
- Testing
- i-Sleep & BioClock, Online Psychoeducation
- Where
- Netherlands
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Drowsiness, Sleep Deprivation
TESTING AN MTM THEORY-BASED INTERVENTION ON REDUCING DROWSY DRIVING BEHAVIOR, "STAY AWAKE, STAY ALIVE ©," AMONG COLLEGE STUDENTS
The goal of this randomized controlled educational study is to learn whether a structured, theory-based program can help reduce drowsy driving among college students (18 years and older) in Nevada.
- Conditions
- Drowsiness, Sleep Deprivation, Fatigue
- Trial name
- NCT07434921
- Testing
- MTM Theory based intervention, Standard AAA Knowledge based
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Narcolepsy
Genetic and Clinical Characterization of Type 1 and 2 Narcolepsy in Adult and Pediatric Black and North African Populations
Narcolepsy type 1 (NT1) is a neurological disorder characterized by excessive daytime sleepiness, cataplexy, sleep paralysis, and hallucinations while awake.
- Trial name
- NarcoGen (NCT06786377)
- Testing
- saliva sampling
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Occupational Health, Sleep
Using Cognitive-Behavioral Change and Mobile Technology to Improve RN Sleep and Fatigue
The U.S. registered nurse (RN) workforce is the largest in the Healthcare and Social Assistance Sector and is at high risk for injuries and errors due to poor sleep and fatigue.
- Conditions
- Occupational Health, Sleep, Fatigue, Nurse
- Trial name
- RN-SLEEP (NCT06105307)
- Testing
- RN-SLEEP, Healthy Habit - Educational Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Effect of Kefir on Healthy Adults
Effects of Kefir Consumption on Health Outcomes: Gastrointestinal System, Immunity, Biochemical Parameters, Body Composition, Sleep Quality and Mental Well Being in Healthy Adults
The goal of this clinical trial is to evaluate the effects of the administration of kefir on gastrointestinal system, mental health, biochemical parameters, immunity and inflammation processes as well as the sleep quality…
- Trial name
- KefirCons (NCT06612164)
- Testing
- kefir
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Medipol University
Sleep Disordered Breathing, Able Bodied
Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment
Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure therapy given the modest efficiency of positive…
- Trial name
- CSA (NCT04118387)
- Testing
- Acetazolamide + supplemental oxygen + PAP therapy, Zolpidem + PAP therapy, Buspirone + PAP therapy
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Mood and Sleep Quality
A Study to Evaluate the Efficacy of VL-NL-02 on Sleep Quality.
The goal of this clinical trial is to study the impact of VL-NL-02 in improving sleep quality, restorative sleep complaints, quality of life, stress levels, and sleep stages.
- Trial name
- NCT06056258
- Testing
- VL-NL-02
- Where
- 5 sites in India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Primary Dysmenorrhea
Yoga Effects in Primary Dysmenorrhea
The goal of this clinical trial was to assess whether a yoga-based exercise program could improve aerobic endurance, sleep quality, and reduce menstrual symptoms and pain in young women aged 18-25 with primary dysmenorrhea.
- Trial name
- NCT07020338
- Testing
- Yoga Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Sleep, Sleep Apnea
Research Framework Exploring Sleep Health
This is a digital health study in which participants are recruited to collect sleep and activity data from digital activity trackers.
- Conditions
- Sleep, Sleep Apnea, Obesity, Mood
- Trial name
- REFRESH (NCT05197738)
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Scripps Translational Science Institute
Sleep Apnea Syndromes
Left Atrial Volume and Function Evaluation in Patients With Obstructive Sleep Apnea
The purpose of this study is to determine whether patients with obstructive sleep apnea have any changes in left atrial morphology and function evaluated by echocardiography three dimensional
- Trial name
- NCT00570115
- Where
- Brazil
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Sleep Deprivation
The Stockholm Sleepy Brain Study: Effects of Sleep Deprivation on Cognitive and Emotional Processing in Young and Old
The main purpose of this study is to investigate the effects of partial sleep deprivation (PSD) on resting state brain connectivity, emotional contagion, empathy, and emotional regulation.
- Trial name
- NCT02000076
- Testing
- Partial sleep deprivation allowing 3 h sleep at night, Full sleep
- Where
- Sweden
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mats Lekander
Sleep, Fatigue
Sleep, Mindfulness, and Shift-Level Safety Performance in Perianesthesia Nurses
Perianesthesia (preoperative and postanesthesia care unit, PACU) nurses work rotating, often extended shifts that can disrupt sleep and increase fatigue, both of which are recognized threats to patient safety in high-acuity…
- Conditions
- Sleep, Fatigue, Patient Safety
- Trial name
- NCT07832721
- Testing
- Sleep, Mindfulness, and Shift-Level Safety Observation Toolkit
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Volkan Gokmen
Insomnia
A Study to Evaluate the Pharmacokinetics of LY2624803 in Subjects With Hepatic Impairment
The purpose of this study is to evaluate the impact of hepatic dysfunction on the pharmacokinetics and safety of LY2624803 and its major metabolite, LSN2797276.
- Trial name
- NCT01257178
- Testing
- LY2624803
- Where
- 4 sites in Germany, Hungary and 1 more
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Sleep Apnea, Obstructive
Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome
The primary objectives of the study are to determine the effectiveness of PROVIGIL treatment, compared to placebo treatment, in children and adolescents with excessive sleepiness (ES) associated with obstructive sleep…
- Trial name
- NCT00107809
- Testing
- Modafinil
- Where
- 64 sites in United States, Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cephalon
Mental Illness, Burnout Syndrome
Physician Mental Health Study for Medical Trainees
The purpose of this study is to determine whether use of a suite of smart phone enabled mobile health devices can reduce burnout in medical trainees.
- Trial name
- NCT02950363
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Scripps Translational Science Institute
Restless Legs Syndrome (RLS)
Effect of Rotigotine Patch Treatment on Cardiovascular Markers in Idiopathic Restless Legs Syndrome
Several studies report association between restless legs syndrome (RLS), HTA and cardiovascular diseases . The mechanisms involved in this relationship remained unknown, but several evidences favor the role of periodic limb…
- Trial name
- NCT01823770
- Testing
- Rotigotine
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Sleep
The Sleep Lengthening and Metabolic Health, Body Composition, Energy Balance and Cardiovascular Risk Study
Short sleep duration has been associated with increased risk of weight gain and development of non-communicable diseases. Sleep deprivation studies have suggested the link between restricted sleep and risk of adiposity and…
- Trial name
- SLuMBER (NCT02787577)
- Testing
- Sleep Lengthening
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- King's College London
Sleep, Sleep Disorder
Language of Sleepiness
Subjects will complete an electronic consent form and then fill out questionnaires on a tablet computer. The answers to the questions will be recorded to a secure electronic database, along with the results of a clinical…
- Conditions
- Sleep, Sleep Disorder, Sleepiness
- Trial name
- NCT04323254
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
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