Clinical trials: Sleep-Wake Disorders
Aging, Sleep Deprivation
Effects of Chronic Sleep Restriction in Young and Older People
The purpose of this study is to examine the consequences of chronic sleep restriction on nighttime sleep, daytime alertness, performance and memory functions, and metabolic and cardiovascular function, and to determine if the…
- Conditions
- Aging, Sleep Deprivation, Metabolic Syndrome
- Trial name
- NCT00506428
- Testing
- chronic sleep restriction
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Postmenopausal Period, Fatigue
The Effect of Progressive Relaxation Exercises on Sleep Quality and Fatigue in Postmenopausal Period
The population of the study will be postmenopausal women who applied to the KETEM unit of a hospital in western Turkey for examination. This study is a two-group randomized controlled study.
- Conditions
- Postmenopausal Period, Fatigue, Sleep Quality
- Trial name
- NCT05483413
- Testing
- progressive relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Obstructive Sleep Apnea, Cognitive Impairment
Prevalence of Obstructive Sleep Apnea (OSA) and the Association With Cognitive Impairment
The study is aimed to carry out an epidemiology study investigating the prevalence of obstructive sleep apnea (OSA) and the association with cognitive impairment.
- Trial name
- NCT04658290
- Where
- Hong Kong
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea, Obstructive Sleep Apnea-hypopnea
Updating Deep Learning Algorithms for OSA Monitoring
The objective is to enhance the reliability of the algorithm to match that of Level 1 polysomnography by leveraging the diverse data obtained from Level 1 polysomnography to refine the deep learning algorithm.
- Trial name
- NCT06522815
- Testing
- CART-I plus, Polysomnography
- Where
- South Korea
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Sky Labs
Sleep Disorder
The Efficacy of Lower Dose Zolpidem for Achieving Satisfactory Sleep in Women With Disordered Sleep
Sleep difficulties are very common in adults in the U.S. today. Zolpidem (Ambien) is often prescribed as a first line agent to treat sleep difficulties in patients presenting with sleep related complaints to Primary Care…
- Trial name
- NCT03786120
- Testing
- Zolpidem
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Post Traumatic Stress Disorder, Insomnia Disorder
RESILIENT : A Self-Managed Online Platform for Victims of Sexual Assault
There are 636,000 self-reported cases of sexual assault annually in Canada, and nine out of ten persons who have experienced sexual assault are women.
- Conditions
- Post Traumatic Stress Disorder, Insomnia Disorder, Major Depressive Disorder
- Trial name
- NCT05811897
- Testing
- Self-Managed Online Treatment, Therapist-Assisted Online Treatment
- Where
- Canada
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Laval University
Depression, Insomnia
Cognitive Behavioral Therapy for Insomnia and Depression Among Menopausal Women
Considering physical and psychological problems that threaten women during the menopausal period, it seems that therapies that can help women cope with these problems, especially psychological ones, will be useful.
- Conditions
- Depression, Insomnia, Cognitive Behavioral Therapy, Menopausal Depression
- Trial name
- NCT05920460
- Testing
- Cognitive Behavioral Therapy Program
- Where
- 2 sites in Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Eating Attitudes, Lifestyle Risk Reduction
Eating, Sleep, Attitudes, and Stress Risk in Physical Therapy Students
The goal of this observational study is to assess how eating attitudes, sleep attitudes, and perceived stress contribute to early indicators of cardiovascular risk among undergraduate physical therapy students aged 18-30.
- Conditions
- Eating Attitudes, Lifestyle Risk Reduction, Perceived Stress
- Trial name
- EHSAR-S (NCT07303244)
- Testing
- complete validated questionnaires
- Where
- Egypt
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sleep Problems
Understanding Sleep Problems in Children With Autism Spectrum Disorder
The investigators will examine whether sleep problems in children with autism spectrum disorder (ASD) are related to alterations in the production of melatonin (MT), a hormone that plays an important role in regulating sleep-wake…
- Trial name
- REST (NCT00691080)
- Where
- 3 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Healthy
Effects of Donepezil and Memantine on Cognitive Functions After a Sleep Deprivation Challenge in Healthy Volunteers
The aim of this study is to assess the utility of sleep deprivation as a potential model for prediction of clinical efficacy using a combination of cognitive physiological endpoints.
- Trial name
- NCT01461174
- Testing
- Modafinil, Donepezil, Memantine
- Where
- 2 sites in France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Qualissima
Restless Legs Syndrome
Glutamate, Hyperarousal and Restless Legs Syndrome
Restless Legs Syndrome (RLS) research has focused on the sensory features and failed to address an important aspect of RLS; i.e. a 'hyperarousal' or profound chronic sleep loss without significant excessive daytime sleepiness.
- Trial name
- NCT01675323
- Where
- 2 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Mood, Anxiety
Clinical Trial to Evaluate Magtein in Older Adults
A randomized double blind placebo controlled trial to evaluate the effects of a specialized magnesium on mood states and sleep quality in older adults.
- Trial name
- NCT02363634
- Testing
- magnesium threonate
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Miami Research Associates
Sleep Disturbance, Sleep Quality
A Double-Blind, Randomized, Placebo-Controlled Study of the Safety and Effects of Various Cannabinoids on Sleep Quality
This double-blind, randomized, placebo-controlled study will assess the safety and effects of different combinations of CBN, CBG, and THC, with and without CBD and melatonin, for enhancing sleep quality, other factors related to…
- Trial name
- NCT07769164
- Testing
- 2 mg THC + 2 mg CBN + 2 mg CBG + 10 mg CBD + 1 mg Melatonin, 10 mg THC + 5 mg CBN + 5 mg CBG + 20 mg CBD, 10 mg THC + 20 mg CBN + 5 mg CBG
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- Cannabis Science Innovations, LLC
Obstructive Sleep Apnea
Adaptation and Validation of Pediatric Sleep Questionnaire (PSQ) in Arabic
The gold-standard in the diagnosis of Sleep-Related Breathing Disorders (SRBDs) is polysomnography, but the time, effort, and expense of laboratory studies has limited relevant research and particularly epidemiological research…
- Trial name
- NCT06141707
- Testing
- Arabic pediatric sleep questionnaire
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Minia University
Sleep Quality , Physical Fitness and Body Mass Index
Correlation Between Sleep Quality , Physical Fitness and Body Mass Index
It is estimated that 10-13% of adults suffer from chronic insomnia. Short sleep duration is linked to obesity, type 2 diabetes, high blood pressure, and cardiovascular diseases.
- Trial name
- NCT06815900
- Testing
- one group .observational study
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Cairo University
Insomnia, Sleep
Blue Blockers at Night and Insomnia Symptoms
Under entrained conditions, humans maintain a consolidated nocturnal sleep episode that coincides with environmental darkness and endogenous melatonin secretion.
- Trial name
- NCT02698800
- Testing
- Blue blocking (BB) lenses, Clear lenses
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obstructive Sleep Apnea
Delphi Consensus Excessive Daytime Sleepiness in OSA
The objective of this study is to generate expert consensus statements on the differential diagnosis, definition, and management of EDS in patients with OSA who are adequately treated with primary therapy.
- Trial name
- NCT05055271
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King's College London
Obstructive Sleep Apnea
Cardiopulmonary Exercise Test in Patient With Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) can be described as a condition characterized by repetitive obstruction of the upper airway resulting in oxygen desaturation and awakening from sleep, loud snoring, and increased daytime sleepiness .
- Trial name
- NCT03300700
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Insomnia, Anesthesia
Orexin-A Levels in Insomnia Patients
In the pathophysiology of insomnia, the increase of the orexin-A (OXA) peptide released from orexin neurons in the lateral hypothalamus plays an important role. Orexins takes part at the emergence of anesthesia.
- Trial name
- NCT05664295
- Testing
- Jenkins Sleep Disorders scale and Epworth Sleepiness scale
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Restless Legs Syndrome (RLS), End-Stage Renal Disease
Effect of Intra-Dialytic Muscle Energy Technique on Restless Leg Syndrome in Hemodialysis Patients
The goal of this clinical trial is to learn if intra-dialytic Muscle Energy Technique (MET) can reduce symptoms of restless legs syndrome (RLS) in people with end-stage renal disease (ESRD) receiving maintenance hemodialysis.
- Trial name
- MET-RLS (NCT07748065)
- Testing
- Muscle Energy Technique, Routine Medical Treatment and Hemodialysis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
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