Clinical trials: Sleeping Efficacy
Sleep Deprivation, Sleep
Effects of Napping in Sleep-Restricted Adolescents
To examine the neurobehavioural responses to two successive cycles of sleep restriction and recovery in adolescents, and to determine the benefits of napping on cognitive performance, alertness, and mood.
- Trial name
- NCT02838095
- Testing
- Nap
- Where
- Singapore
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Sleep Apnea, Obstructive
Study of Provent Treatment of Obstructive Sleep Apnea in Patients Who Are Non-compliant With CPAP
The primary objective of the proposed investigation is to evaluate the efficacy of the Provent device in a sample of OSA patients who have either refused or been non-adherent with PAP treatment.
- Trial name
- NCT00901771
- Testing
- Provent
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- St. Luke's Hospital, Chesterfield, Missouri
Menopause, Hot Flashes
Randomized Evaluation of Natural Extract for Menopausal Wellness (RENEW)
This study will evaluate whether an 8-week course of a standardized herbal extract containing Shatavari and natural bio-enhancer ingredients can reduce menopausal symptoms in post-menopausal women.
- Trial name
- RENEW (NCT07834463)
- Testing
- Shatavari (Asparagus racemosus) Extract
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- India Glycols Ltd
Bruxism
Study of the Safety and Efficacy of Botox in Bruxism
The purpose of this study is to determine whether botulinum toxin helps patients with bruxism.
- Trial name
- NCT00908050
- Testing
- Botulinum toxin type A
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Baylor College of Medicine
Sleep Disorder
Safety and Efficacy of Ramelteon in Healthy Subjects
The purpose of this study is to determine the phase-advance in circadian rhythms in healthy adults subjects taking ramelteon, once daily (QD).
- Trial name
- NCT00671190
- Testing
- Ramelteon
- Where
- 13 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Takeda
Cancer, Insomnia
Efficacy of Auricular Pressure Beans with Electroacupuncture and Estazolam Treating Insomnia Caused by Cancer
The core objectives of this study are to assess the short-term and long-term efficacy of auricular acupoint pressure beans combined with electroacupuncture and estazolam in the treatment of cancer-caused insomnia.
- Trial name
- NCT06859190
- Testing
- estazolam 1-2 mg, Auricular pressure bean combined with electroacupuncture
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Qinghai Red Cross Hospital
Insomnia Chronic, Oppositional Defiant Disorder
SLEEP-COPE: Sleep Intervention for Oppositional Children
Children with Oppositional Defiant Disorder (ODD) are at risk for insomnia, arousal dysfunction, mood problems, and noncompliance.
- Trial name
- NCT06350292
- Testing
- SLEEP: COPE
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of South Florida
Insomnia Chronic, Insomnia Disorder
Digital CBT-I for Chronic Insomnia
This study evaluates the effectiveness and safety of a digital Cognitive Behavioral Therapy program for Insomnia (CBT-I) in individuals with chronic insomnia.
- Trial name
- NCT06695000
- Testing
- digital CBT-I
- Where
- 5 sites in South Korea
- Volunteers
- 120 people
- Sponsor
- WELT corp
Obstructive Sleep Apnea
AD109 Dose Finding in Mild to Moderate OSA
This is a randomized, 3-period, placebo-controlled, crossover, phase 2 clinical study to examine the efficacy and safety of 2 doses of AD109 vs placebo in patients with mild obstructive sleep apnea.
- Trial name
- NCT04631107
- Testing
- AD109 dose1- A, AD109 dose2- B
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Apnimed
Landau-Kleffner Syndrome, Status Epilepticus, Electrographic
Efficacy Study of Acetazolamide Versus Diazepam in Continuous Spike and Wave/Landau-Kleffner Syndrome
The purpose of this study is to compare the effectiveness of the medications acetazolamide and diazepam in the treatment of continuous spike wave in sleep (CSWS) and Landau-Kleffner syndrome (LKS).
- Trial name
- NCT02904265
- Testing
- Diazepam, Acetazolamide
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic
Obstructive Sleep Apnea of Adult
Cost-effectiveness Analysis and Conditional Response to the Effect of Positional Devices in Obstructive Sleep Apnea
The objectives of this study are: To assess the effectiveness and cost-effectiveness of a vibrating positional device (NightBalance, Philips) in the treatment of positional obstructive sleep apnea compared to conventional CPAP…
- Trial name
- NCT05268471
- Testing
- Positional device (PD), Continuos Positive Airway Pressure (CPAP)
- Where
- Spain
- Volunteers
- 154 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Obesity, Diabetes
Ketogenic Diet Treatment of Obesity With Co-morbid Type 2 Diabetes Mellitus and/or Obstructive Sleep Apnea
The purpose of the study is to evaluate the efficacy and safety of ketogenic diet (KD) treatment of (i) obesity, (ii) type 2 diabetes mellitus and (iii) obstructive sleep apnea (OSA) in patients with obesity and Type 2 DM and in…
- Conditions
- Obesity, Diabetes, Obstructive Sleep Apnea
- Trial name
- KGDobesity (NCT02069197)
- Testing
- Ketogenic diet, Orlistat, Standardized diet
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Mid-Atlantic Epilepsy and Sleep Center, LLC
Insomnia Chronic, Older People
Efficacy of Trazodone to Treat Insomnia in Older Adults (TRADITION Study)
This study aims to evaluate how effective trazodone is in treating insomnia in adults aged 65 years and older. The main question it aims to answer is : Is trazodone more effective than a placebo in reducing the severity of…
- Conditions
- Insomnia Chronic, Older People, Drug Therapy
- Trial name
- TRADITION (NCT06983080)
- Testing
- Trazodone 25 mg
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Obstructive Sleep Apnea
Treatment of OSA Associated Hypertension With Alpha 2 Agonist or Diuretic
Patients who have obstructive sleep apnea (OSA) frequently stop breathing while they sleep. They often develop high blood pressure. We are not sure what drug is best to treat the high blood pressure.
- Trial name
- guanhctz (NCT02699125)
- Testing
- Guanfacine, Hydrochlorothiazide
- Volunteers
- 41 people
- Sponsor
- University of California, San Diego
OSAHS, Oropharyngeal Muscle Training
Exploring the Clinical Efficacy of Remote Management Applications Through Comprehensive Physical Therapy for Patients With Moderate to Severe Sleep Apnea
To observe comprehensive physical therapy program for OSAHS patients
- Conditions
- OSAHS, Oropharyngeal Muscle Training, Aerobic Exercise, Comprehensive Physical Therapy
- Trial name
- NCT06413940
- Testing
- Myofunctional Therapy, Inspiratory Muscle Training, Aerobic Exercise
- Volunteers
- 105 people
- Sponsor
- China National Center for Cardiovascular Diseases
Sleep
The Effectiveness of a Proprietary of a Botanical Extract on Sleep Quality
The purpose of this study is to evaluate the efficacy and superiority of a botanical based sleep product on sleep quality as compared to melatonin, among healthy female participants.
- Trial name
- NCT06894108
- Testing
- Proprietary Blend of Botanical Extracts, Melatonin
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Fatigue
Evaluate the Effectiveness and Safety of the Alpinia Galanga Formulation, Theacrine Formulation, and Caffeine Formulation on Fatigue, Mental Acuity, and Cognitive Health
The purpose of this study is to assess the effectiveness and safety of the Alpinia galanga formulation, Theacrine formulation, and Caffeine formulation on fatigue, mental acuity, and cognitive health among overall healthy…
- Trial name
- NCT05170113
- Testing
- Alpinia galanga formulation, Theacrine formulation, Caffeine formulation
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Regular Physical Activity, Exercise
Investigation of the Effectiveness of Regular Physical Activity in University Students
In our study, university students who coded the course from various faculties and departments within the scope of a university-wide free elective course, after regular physical activity; It was aimed to examine the effects on…
- Trial name
- NCT06329115
- Testing
- Exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Obesity Hypoventilation Syndrome
AVAPS-AE Efficacy Study
The purpose of this study is to evaluate the feasibility of using of the Average Volume Assured Pressure Support (AVAPS-AE) mode versus Continuous Positive Airway Pressure (CPAP) and bilevel pressure support ventilation (PSV)…
- Trial name
- NCT01368614
- Testing
- AVAPS-AE Mode of Therapy, Respironics OnmiLab BiPAP S mode, Respironics OmniLab Advanced CPAP mode
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Philips Respironics
Menopause, Hot Flashes
Study Evaluating DVS-233 SR to Treat Vasomotor Systems Associated With Menopause
The purpose of this study is to assess the safety and efficacy of desvenlafaxine succinate (DVS) for treatment of moderate to severe vasomotor symptoms (VMS) that are associated with menopause, and also to assess the effects of…
- Conditions
- Menopause, Hot Flashes, Sleep Disorders
- Trial name
- NCT00256685
- Testing
- DVS-233 SR
- Volunteers
- 568 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
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