Clinical trials: Sleeping Efficacy
Pain, Postoperative
Evaluate Analgesic/Sedative Efficacy of Naproxen Sodium and Diphenhydramine in Patients With Postsurgical Dental Pain
The objective of the study is to evaluate the efficacy and safety of a single oral dose of two dose combinations of naproxen sodium and diphenhydramine (DPH) to demonstrate that naproxen sodium/DPH combination provides added…
- Trial name
- Morpheus II (NCT01280591)
- Testing
- Naproxen sodium 440 mg / DPH 50 mg (BAY98-7111), Naproxen sodium 220 mg / DPH 50 mg (BAY98-7111), Naproxen sodium 440 mg (BAYH6689)
- Where
- 2 sites in United States
- Volunteers
- 712 people
- Sponsor
- Bayer
Physical Activity, Obesity
Effectiveness of a Physical Activity Intervention to Prevent Obesity and Improve Academic Performance
Coordinated project whose objectives are: a) to test the effectiveness of a promotion of physical activity intervention (MOVI-KIDS) on preventing obesity; and b) to improve the academic performance in both children with and…
- Conditions
- Physical Activity, Obesity, Children, Academic Underachievement Disorder
- Trial name
- MOVI-KIDS (NCT01971827)
- Testing
- MOVI-KIDS
- Where
- Spain
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Obstructive Sleep Apnea, PTSD
Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD
Approximately 20 million Americans suffer from Obstructive Sleep Apnea (OSA) creating risks for major health problems, including dementia, heart attack, and stroke.
- Conditions
- Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
- Trial name
- NCT02641496
- Testing
- CBT-OSA, Sleep Education
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Sleep Apnea Syndromes
Effectiveness of VistaO2 Device in Screening of Sleep Apnea/Hypopnea Syndrome
The high prevalence (9% in men and 4% in women) of sleep apnea / hypopnea syndrome (SAHS) in adults is now well documented as well as its cardiovascular repercussions.
- Trial name
- VISTAO2 (NCT01135303)
- Testing
- VistaO2 device
- Where
- 2 sites in France
- Volunteers
- 182 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Major Depressive Disorder (MDD) With Insomnia
Efficacy of Chronotherapeutic Combination for Major Depressive Episode With Insomnia
Major Depressive Disorder (MDD) affects 5% of the global population and is the second leading cause of disability worldwide. Despite the widespread use of antidepressants, 50-60% of patients do not respond adequately after 8…
- Trial name
- CombiChronoS (NCT07120880)
- Testing
- AD + SHR + active LT and extended-release melatonin 2mg
- Where
- France
- Volunteers
- 184 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Insomnia
Study on the Efficacy and Safety of Anesthesia-Induced Sleep Therapy for Refractory Insomnia
The incidence of refractory insomnia is rising annually, with traditional therapies offering limited efficacy. Anesthesia-Induced Sleep (AIS), involving anesthetic infusion like dexmedetomidine, is emerging.
- Trial name
- NCT07255027
- Testing
- Dexmedetomidine and conventional oral drug, Conventional oral drug therapy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Breast Cancer Female, Insomnia
Comparative Effectiveness Feasibility Trial for Insomnia Among Breast Cancer Survivors
Women with breast cancer who report insomnia that started or worsened during breast cancer diagnosis and treatment will be enrolled in a group behavioral trial to one of two arms testing cognitive behavioral therapy for insomnia…
- Trial name
- NCT03328169
- Testing
- Mindfulness-Based Therapy, Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- George Washington University
Autism Spectrum Disorders
Examining the Efficacy of Mattress Technology in Improving the Sleep Quality of Children With ASD
The purpose of the present study is to evaluate the tolerability and efficacy of the Sound To Sleep System™ in improving the sleep quality of children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT02739321
- Testing
- Sound to Sleep System
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
Obstructive Sleep Apnea, Obesity
Obstructive Sleep Apnea Master Protocol GPIF: A Study of Tirzepatide (LY3298176) in Participants With Obstructive Sleep Apnea
The purpose of this study is to evaluate the effect and safety of tirzepatide in participants with moderate to severe obstructive sleep apnea and obesity who are both unwilling or unable to use Positive Airway Pressure (PAP)…
- Trial name
- SURMOUNT-OSA (NCT05412004)
- Testing
- Tirzepatide
- Where
- 58 sites in United States, Australia and 8 more
- Volunteers
- 469 people
- Sponsor
- Eli Lilly and Company
Minority Stress, Psychological Stress
Effect of Ashwagandha Root Extract on Stress, Anxiety, and Sleep Quality in Adults Experiencing Minority Stress
Sexual and gender minority adults often experience elevated levels of chronic stress due to stigma, discrimination, and social adversity, commonly referred to as minority stress.
- Conditions
- Minority Stress, Psychological Stress, Anxiety
- Trial name
- NCT07441070
- Testing
- Ashwagandha Root Extract
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- SF Research Institute, Inc.
Stroke, Sleep
Personalised Sleep and Circadian Intervention After Stroke
This is a two-arm, parallel-group randomized controlled feasibility trial involving 40 community-dwelling adults with chronic stroke and ongoing sleep or circadian difficulties.
- Trial name
- NCT07731516
- Testing
- ISleepFAST, Stroke and Sleep Health Education
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Chronic Insomnia
REST: Restoring Effective Sleep Tranquility in College Veterans With Service-Related Injuries
The purpose of the project is to improve the sleep quality and sleep duration of post 9/11 veterans seeking college degrees. Preliminary research findings within CSU's New Start for Student Veterans program indicate veterans with…
- Trial name
- NCT02871414
- Testing
- REST - Early Group, REST - Late Group
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Colorado State University
Insomnia
Effectiveness of eCBT-I on Improving Mental Health in Chinese Youths With Insomnia
This study aims to conduct a randomized control trial to validate the treatment effect of e-based cognitive behavioral therapy for Insomnia (e-CBT-I) on insomnia disorder, and explore whether e-CBT-I could prevent depression and…
- Trial name
- NCT04069247
- Testing
- e-CBT-I, e-HE
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 708 people
- Sponsor
- Chinese University of Hong Kong
Sleep Breathing Disorders
A Clinical Trial Evaluating the Effectiveness and Safety of a mmWave Radar Based Sleep Respiratory Monitoring System
This study compares the diagnostic capability of a millimeter-wave radar-based Sleep Respiratory Monitoring System to the gold standard polysomnography.
- Trial name
- NCT06038006
- Testing
- Sleep Respiratory Monitoring System
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Changsha Tsingray Technology Co., Ltd.
Obstructive Sleep Apnea, Non-small Cell Lung Cancer
Obstructive Sleep Apnea Influences Efficacy of PD-1-Based Immunotherapy Against Non-Small Cell Lung Cancer
This prospective, observational cohort study aims to explore the influence of obstructive sleep apnea(OSA) on the efficacy of PD-1-based immunotherapy in patients with non-small cell lung cancer(NSCLC).
- Trial name
- NCT04743752
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Insomnia
Effectiveness of Mindfulness Based Cognitive Therapy (MBCT) on for Insomnia and Mental Health of Prisoners
Insomnia is highly prevalent in prisoners and is a risk factor for poor mental well-being, depression, suicidality and aggression, all common concerns in this vulnerable population.
- Trial name
- NCT04134949
- Testing
- Cognitive Behavior Therapy, Mindfulness-Based Cognitive Therapy
- Where
- 2 sites in Iran
- Volunteers
- 140 people
- Sponsor
- Qazvin University Of Medical Sciences
Sleep Disorder
The Efficacy of Lower Dose Zolpidem for Achieving Satisfactory Sleep in Women With Disordered Sleep
Sleep difficulties are very common in adults in the U.S. today. Zolpidem (Ambien) is often prescribed as a first line agent to treat sleep difficulties in patients presenting with sleep related complaints to Primary Care…
- Trial name
- NCT03786120
- Testing
- Zolpidem
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Opiate Dependence
Clinical Efficacy and Serum Proteomic Profiling of Suan-Zao-Ren Tang for Sleep Disturbance During Methadone Maintenance
The purpose of this study is to evaluate the efficacy of Suan-Zao-Ren Tang in improving sleep quality, anxiety, depression, and heroin craving among methadone-maintained persons with sleep complaints.
- Trial name
- NCT01913418
- Testing
- Suan-Zao-Ren Tang
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- China Medical University, Taiwan
Sleep Apnea, Obstructive
A Study of IBI362 in Chinese Subjects With Obstructive Sleep Apnea and BMI≥28 kg/m2
This is a multicenter, randomized, double-blind, placebo-controlled Phase III clinical study to evaluate the efficacy and safety of IBI362 in subjects with moderate-to-severe obstructive sleep apnea (OSA) and a body mass index…
- Conditions
- Sleep Apnea, Obstructive, Obesity
- Trial name
- NCT06931028
- Testing
- IBI362
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Innovent Biologics (Suzhou) Co. Ltd.
Insomnia
Investigation of the Safety and Efficacy of Long Term Administration of Eszopiclone in Insomnia Patients
To investigate the safety and efficacy of administration of eszopiclone for 6 months in insomnia participants.
- Trial name
- NCT02455271
- Testing
- Eszopiclone
- Where
- 2 sites in Japan
- Volunteers
- 438 people
- Sponsor
- Eisai Co., Ltd.