Clinical trials: Sleeplessness
Heart Rate Variability, Insomnia Chronic
Discussion on Pulse Diagnosis and Heart Rhythm Variability of Patients With Chronic Insomnia
Discuss the objective assessment of patients with insomnia by pulse diagnosis, and measure by subjective questionnaire and physiological instruments.
- Trial name
- NCT05745519
- Testing
- Pittsburgh sleep quality index (PSQI), ANSWatch
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Mental Disorder, Mental Stress
Virtual Agents-based Digital Interventions to Improve Health
KANOPEE is a free smartphone application providing screening, follow-up tools and autonomous digital interventions to lower psycho-social stress and its repercussions on sleep and behaviors in the general population.
- Conditions
- Mental Disorder, Mental Stress, Insomnia, Depression
- Trial name
- KANOPEE (NCT05074901)
- Testing
- digital behavioral intervention
- Where
- France
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Insomnia Disorder, Circadian Rhythm Sleep Disorder
The Sleep Clinic Outcome and Practice Study
The goal of this clinical trial is to explore the outcome and practice treatment for sleep-wake disturbances in a Sleep Clinic. The main questions it aims to answer are: What is the practice (timing and duration of treatment…
- Trial name
- SUP (NCT06669507)
- Testing
- Chronotherapy, Cognitive Behavioral Therapy for Insomnia
- Where
- Norway
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Insomnia, Sleep Disorder
Efficacy and Safety Study of Propofol Infusion for Refractory Chronic Primary Insomnia
Insomnia is a widespread condition in which approximately one-third of adults in the United States are symptomatic with 6% of the population meeting the diagnostic criteria for insomnia.
- Conditions
- Insomnia, Sleep Disorder, Dyssomnia
- Trial name
- NCT02043977
- Testing
- propofol injectable emulsion
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Life Extension Foundation Inc.
Major Depressive Disorder, Insomnia
Quetiapine Extended Release (XR) for the Treatment of Menopausal Depression
The study was designed to examine the efficacy and tolerability of quetiapine XR for the treatment of women who suffer from depression in the context of the menopausal transition and postmenopausal years.
- Conditions
- Major Depressive Disorder, Insomnia, Hot Flashes
- Trial name
- NCT00723970
- Testing
- Quetiapine Extended Release
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- McMaster University
Insomnia, Circadian Rhythm Disorders
Older Adults Exercising On Time
There are indications from epidemiological cohort studies and animal experiments that timing of physical activity (also referred as "chronoactivity"), irrespective of intensity, impacts health and disease.
- Trial name
- ON TIME (NCT06613958)
- Testing
- Physical activity timing
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Insomnia, Hepatic Insufficiency
Pharmacokinetics of Suvorexant in Participants With Hepatic Insufficiency (MK-4305-017)
This study will determine whether the plasma concentration-time profile and pharmacokinetics (PK) of suvorexant (MK-4305) in participants with moderate and mild hepatic insufficiency are similar to those observed in healthy…
- Trial name
- NCT01043926
- Testing
- Suvorexant
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Frail Elderly
Effect of Hot Water Foot Bath on Daily Living Activities, Insomnia and Fatigue Levels in Frail Geriatric Individuals
Aim: A randomized controlled experimental study was conducted to determine the effect of hot water foot bath on daily living activities, sleep and fatigue levels in frail geriatric individuals.
- Trial name
- NCT07048015
- Testing
- Hot Water Foot Bath
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Insomnia, Related Distress Among Cancer Caregivers
Study of Cognitive Behavioral Therapy for Insomnia (CBT-I) and Acupuncture for Insomnia and Related Distress Among Cancer Caregivers
The other aim of this study is to determine which of those two treatments (acupuncture or cognitive behavioral therapy) works better for treating insomnia in Informal Caregivers of cancer patients.
- Trial name
- NCT03012425
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Acupuncture, questionnaires
- Where
- 3 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Insomnia
Overcoming Insomnia: Impact on Sleep, Health and Work of Online CBT-I
Insomnia is a major public health concern. While cognitive behavior therapy for insomnia (CBT-I) is acknowledged as the best available intervention, there are unanswered questions about its wider dissemination, socio-economic…
- Trial name
- NORSE-3 (NCT02558647)
- Testing
- CBT for insomnia (CBT-I), Psycho-Education about Sleep (PE)
- Where
- 2 sites in Norway
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Insomnia, Chronic Pain
A Cognitive-Behaviour Therapy (CBT) Self-Management Approach for Insomnia in Chronic Pain: A Randomized Control Trial
This study will test the impact of a cognitive-behavioural self-management approach for the management of insomnia among patients with chronic pain.
- Trial name
- NCT01188460
- Testing
- Self-help manual for insomnia, Sleep diary
- Where
- 2 sites in Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Insomnia
Long-term Follow-up of Functional Performance and Exercise Efficacy in Community-dwelling Elderly With Insomnia
Poor sleep quality has been recognized as a major public health concern in the world. The prevalence of insomnia in Taiwan is comparable to that of Western countries.
- Trial name
- NCT01689818
- Testing
- exercise training
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Sleep Disorder, Chronic Insomnia
Effectiveness of Music Therapy on Sleep Disorders
The purpose of this study is to determine whether listening to music before falling asleep can improve sleep quality in patients with sleep disorders.
- Trial name
- NCT04578860
- Testing
- Music therapy with Music Care app, Sound therapy with White Noise, Treatment as usual for sleep disorders
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Versailles Saint-Quentin-en-Yvelines University
Insomnia, Trauma, Psychological
A Pilot Evaluation of the Insomnia Coach Mobile App
This pilot study is designed to test the feasibility, acceptability, and potential effectiveness of a mobile phone application (app) developed by the VA National Center for PTSD (VA NCPTSD) for use by Veterans with insomnia.
- Trial name
- NCT03826849
- Testing
- Insomnia Coach
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Insomnia
Cognitive-Behavioural and Hypnotic Treatment of Chronic Primary Insomnia Among the Elderly
The present study examines the short- and long-term clinical efficacy of cognitive-behavior therapy and pharmacological treatment in patients suffering from late-life primary insomnia.
- Trial name
- NCT00295386
- Testing
- Cognitive behavior therapy (CBT), Zopiclone
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Bergen
Depression, Anxiety
Melissa Officinalis L. Supplementation for Emotional Health and Sleep Disturbance
This study is aimed to investigate if Lemon Balm Extract supplementation is beneficial for the relief of stress, depression and anxiety in healthy adults.
- Conditions
- Depression, Anxiety, Stress, Insomnia
- Trial name
- NCT05602688
- Testing
- Lemon Balm Supplement
- Where
- Pakistan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ayub Teaching Hospital
Wheel-chair Dependent Elders
Improvement and Mechanism of Wheel-chair Music Aerobic Exercise on Depression and Insomnia Among the Elderly in Long-term Care Facilities
Investigators anticipate to develop a customized WC-MAE for the improvement of insomnia and depression in wheel-chair dependent elders, and to identify related mechanisms as biomarkers for prediction and prevention of insomnia…
- Trial name
- NCT02256020
- Testing
- Original lifestyle, Wheel-chair music aerobic exercise (WC-MAE)
- Where
- Taiwan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Chang Bing Show Chwan Memorial Hospital
Shift Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder
Recovery and Early Sleep Tracking Using the SuperPatch REM Patch
A Phase 1 Feasibility Study of the SuperPatch REM Patch for Post-Night-Shift Sleep Recovery in NHS Doctors
- Conditions
- Shift Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder, Shift Work Sleep Disorders
- Trial name
- REST (NCT07785960)
- Testing
- SuperPatch REM Patch
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SuperPatch Limited LLC
Insomnia
Effect of Activated Charcoal and Time of Dose on the Pharmacokinetics of LY2624803 in Healthy Subject
The purpose of this study is to determine the effect of activated charcoal and dosing time on the absorption of LY2624803 in healthy subjects.
- Trial name
- NCT01236105
- Testing
- LY2624803, Activated Charcoal
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Quality of Life, Insomnia
The Efficacy of Group-based Unified Protocol (UP) Programme for Improving Sleep and Mental Health
Common mental disorders can be disabling and lead to a large burden of disease. Unified Protocol for Transdiagnostic Treatment of Emotional Disorders was developed to address emotional disorders with evidence-based…
- Conditions
- Quality of Life, Insomnia, Depression, Anxiety
- Trial name
- NCT05394753
- Testing
- Unified Protocol for mood disorders
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong