Clinical trials: Small Aortic Annulus
Small Aortic Annulus, Aortic Root Enlargement Procedure
Modified Aortic Root Enlargement Procedure
This study is a prospective observational clinical trial, in which severe AS patients aged 50-70 years with SAA choose modified ARE or TAVR according to their wishes to investigate the safety and efficacy of modified ARE; Compare…
- Trial name
- NCT06517537
- Where
- China
- Volunteers
- 64 people
- Sponsor
- China National Center for Cardiovascular Diseases
Severe Aortic Valve Stenosis
In-vitro Benchmarking of Currently Available Heart Valve Prostheses for Surgical and Percutaneous Treatment of Aortic Stenosis With Small Annulus, Followed by In-vivo Validation
The general objective of this study is to compare in vitro and in vivo the hemodynamic performance of different types of aortic valve prostheses and possible surgical implantation techniques.
- Trial name
- SurPASS (NCT06859255)
- Testing
- MRI
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Policlinico S. Donato
Aortic Stenosis
Anatomical Determinants and Outcomes of Small Annulus Patients Undergoing TAVR in Different ASIAN Ethnicity
Transcatheter aortic valve implantation (TAVI) presents unique challenges for Asian patients compared to Caucasians, largely due to the prevalence of small aortic annulus (SAA) defined based on Caucasians' data (430 mm²)…
- Trial name
- NCT07240025
- Where
- Hong Kong
- Volunteers
- 31 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Aortic Valve Replacement
Aortic Root Enlargement in Aortic Valve Replacement
Aortic valve disease is a progressive illness that varies from minor valve thickening lacking obstruction of blood stream to severe calcification and alteration of the valve leading to weakened leaflet motion.
- Trial name
- NCT03603483
- Testing
- procedure
- Volunteers
- 40 people
- Sponsor
- Assiut University
Aortic Valve Stenosis
Balloon- Versus Self-Expanding Intraannular TAVI in Small Aortic Annuli
In Europe TAVI is now recommended for treatment of aortic valve stenosis from the age of 70 years. When performing TAVI in young patients, lifetime management becomes important in terms of anticipated TAVI-in-TAVI procedures when…
- Trial name
- BALANCE (NCT07794306)
- Testing
- Meril Octapro+ THV System, Abbott Navitor/Navitor Vision THV system
- Where
- Germany
- Volunteers
- 510 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Severe Aortic Valve Disease, Aortic Valve Replacement (AVR)
Comparative Research of Y-Incision vs. Standard Techniques for Aortic Root EnLargement
Abstract Background: Aortic valve replacement (AVR) is crucial for patients with severe aortic valve disease. However, managing those with a small aortic annulus (SAA, i.e., annulus diameter < 22 mm) is challenging because…
- Conditions
- Severe Aortic Valve Disease, Aortic Valve Replacement (AVR), Small Aortic Annulus
- Trial name
- CRYSTAL (NCT07368322)
- Testing
- Y incision Technique (YIT), Standard surgical enlargement techniques
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- willner nadav MD
Aortic Valve Replacement
Small Aortic Annulus - a New Solution to the Old Problem
In this prospective single-center study included 60 patients with a severe degenerative aortic stenosis and small aortic annulus (<21 mm) who underwent standard AVR with stented bioprosthesis (group 1, n=30) and aortic valve…
- Trial name
- NCT03258333
- Testing
- aortic valve replacement
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- The Federal Centre of Cardiovascular Surgery, Russia