Clinical trials: Small Bowel Crohn's Disease
Crohn Disease, Ultrasound Therapy; Complications
Correlation of Cross Sectional Imaging and Small Intestinal Contrast Ultrasonography in Known Crohn's Disease
Small intestinal contrast ultrasound (SICUS) is a modality of intestinal ultrasound (IUS) which does not require any parenteral administration of contrast agent but requires ingestion of around 500 ml of polyethylene glycol…
- Conditions
- Crohn Disease, Ultrasound Therapy; Complications, Computed Tomography, Magnetic Resonance Imaging
- Trial name
- CACTUS-CD (NCT06125678)
- Testing
- Small intestinal contrast enhanced ultrasound followed by Computed tomography/Magnetic resonance enterography
- Where
- India
- Volunteers
- 407 people
- Sponsor
- Asian Institute of Gastroenterology, India
Crohn Disease
The Effects of Bifidobacterium Breve Bif195 for Small Intestinal Crohn's Disease
The purpose of this study is to investigate if the probiotic Bifidobacterium breve Bif195 (Bif195) will result in improvement in clinical outcome in patients with small intestinal Crohn's disease.
- Trial name
- NCT04842149
- Testing
- Bif195 capsules
- Where
- Denmark
- Volunteers
- 33 people
- Sponsor
- Hvidovre University Hospital
Crohn's Disease
Wireless Capsule Endoscopy in Small-Bowel Crohn's Disease
The purpose of this study is to determine the best role for capsule endoscopy in diagnosing Crohn's disease.
- Trial name
- NCT00178438
- Testing
- Capsule Endoscopy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester
Gastrointestinal Hemorrhage, Crohn Disease
Prucalopride Prior to Small Bowel Capsule Endoscopy
Small bowel capsule endoscopy is a test used to investigate for any abnormalities in the small bowel. The small bowel is about 4 meters long. The battery time of the capsule is about 8 hours.
- Conditions
- Gastrointestinal Hemorrhage, Crohn Disease, Celiac Disease, Intestinal Diseases
- Trial name
- NCT02806206
- Testing
- Prucalopride
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- University of British Columbia
Crohn's Disease
Assessment of Small Bowel Healing in Crohn's Disease Patients Treated With Cimzia Using Wireless Capsule Endoscopy
Wireless Capsule Endoscopy has been the most reliable diagnostic standard for small bowel Crohn's disease. Endoscopic healing is an important endpoint to measure response to treatment.
- Trial name
- NCT01053559
- Testing
- certolizumab pegol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Shafran Gastroenterology Center
Crohn Disease
Intraoperative Ultrasound in Crohn's Disease
To study the role of intraoperative ultrasound of small bowel as a possible tool that can reduce the rate of histologically involved resection margins from Crohn's Disease.
- Trial name
- NCT06388057
- Testing
- Intraoperative Small Bowel Ultrasonography
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Crohn Disease
A Comparative Study of MRI, US and CE for Assessing Treatment Response in Known Crohn's Disease
The aim of this study is to evaluate non-invasive imaging techniques for assessing treatment response in known Crohn's disease. 1.
- Trial name
- NCT03435016
- Testing
- Diagnostic work-up
- Where
- Denmark
- Volunteers
- 62 people
- Sponsor
- Sygehus Lillebaelt
Crohn Disease
Evaluation of Small Bowel Colon Capsule for Bowel Visualization in Crohn's Disease Patients
Study Hypothesis: It is estimated that by re-programming some of the PillCam COLON2 system parameters it can serve as tool for visualizing both small bowel and colon.
- Trial name
- SBC-CD (NCT01233310)
- Where
- 4 sites in Israel
- Volunteers
- 26 people
- Sponsor
- Medtronic - MITG
Crohn's Disease
PillCam® Platform With the PillCam Crohn's Disease Capsule
This is a prospective, multi-center (up to 6 sites) study which aims to To establish the effectiveness of the PillCam Platform with the PillCam Crohn's capsule as demonstrated by visualizing the small bowel and colon in patients…
- Trial name
- NCT01631435
- Testing
- Pillcam colon capsule and PillCam™ Prep Procedure, Ileocolonoscopy
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Medtronic - MITG
Small Bowel Crohn's Disease
Combined [18F]-FDG PET-MRI in Diagnostics and Surveillance of Small Bowel Crohn's Disease
Patients with suspected small bowel Crohn's disease (CD) are assessed with PET-MRE using 18-fluorodeoxyglucose ([18F]-FDG) tracer.
- Trial name
- CD-PET (NCT06796959)
- Where
- Finland
- Volunteers
- 35 people
- Sponsor
- Turku University Hospital
Crohns Disease
Comparative Effectiveness of MR Enterography
The purpose of this study is to determine the efficacy of ultrasound imaging compared to MRE (Magnetic Resonance Enterography) a form of magnetic resonance imaging (MRI) in accurately diagnosing and following Small Bowel Crohn…
- Trial name
- NCT01593462
- Testing
- MRE (magnetic resonance enterography), The Ultrasound scan, (UEI) Ultrasound Elastography Imaging with ARFI (acoustic radiation force impulse), Study Questionnaires
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Crohn's Disease
Diagnostic Accuracy of Capsule Endoscopy in Small Bowel Crohn's Disease
Prospective study to compare in a blinded fashion four different diagnostic modalities to detect active small bowel Crohn's disease: a) colonoscopy with ileoscopy; b) small bowel follow through; c) capsule endoscopy; and d)…
- Trial name
- NCT00588653
- Testing
- Capsule endoscopy, CT enterography, colonoscopy, small bowel follow-through
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Mayo Clinic
Crohns Disease
A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Crohn Disease on Advanced Therapies
Advanced therapies including biologics and small molecules target specific inflammatory pathways. IBD's multifactorial etiology means that blocking a single pathway may not be sufficient for all patients.
- Trial name
- BOOST-CD (NCT06890637)
- Testing
- Fecal Microbial Transplantation, Crohns Disease Exclusion Diet, Advanced therapy
- Where
- 6 sites in India
- Volunteers
- 168 people
- Sponsor
- All India Institute of Medical Sciences
Crohn's Disease
The Use of Small Bowel Ultrasound to Predict Response to Remicade Induction
Small bowel ultrasound (SBUS) is emerging as a well tolerated, non-invasive, radiation free, low cost measure to assess inflammatory bowel disease (IBD), and is being used as first-line imaging in Europe.
- Trial name
- NCT02488005
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Crohn Disease
Contrast Ultrasound of the Small Intestine in Patients With Crohns Disease
The purpose of this study is to determine how relevant dynamic ultrasound scans using contrast agents (SonoVue) is in the diagnosis of Crohns disease in the small bowel, compared to dynamic Magnetic Resonance Imaging (MRI) of the…
- Trial name
- KULT (NCT01365767)
- Where
- 2 sites in Denmark
- Volunteers
- 5 people
- Sponsor
- Rune Wilkens
Crohn's Disease, Short Bowel Syndrome
Citrulline: A Plasmatic Marker to Assess and Monitor Small Bowel Crohn's Disease Patients
Citrulline is an amino acid produced in the intestine and in the liver, but the liver does not contribute significantly to circulating citrulline concentrations.
- Conditions
- Crohn's Disease, Short Bowel Syndrome, Malabsorption Syndromes, Celiac Disease
- Trial name
- NCT00138879
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- St Mark's Hospital Foundation
Crohn's Disease
Controlled Trial of 4-Aminosalicylic Acid in Patients With Small Bowel Crohn's Disease
OBJECTIVES: I. Assess the efficacy and safety of 4-aminosalicylic acid in patients with active Crohn's disease of the small bowel.
- Trial name
- NCT00004423
- Testing
- -aminosalicylic acid
- Volunteers
- 80 people
- Sponsor
- University of Vermont
Inflammatory Bowel Disease, Crohn's Disease
The Role of Small Bowel Ultrasound in Initiation of Infliximab in Crohn's Disease Patients
Goal is to prospectively determine if stool calprotectin and change in bowel wall thickness and hyperemia, as seen on small bowel ultrasound, at week 0, 14, and 54 can be used to predict response at week 54 to infliximab in…
- Trial name
- NCT02330458
- Testing
- Small bowel ultrasound
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Small Bowel Crohn's Disease
Assessment of Capsule Endoscopy Scoring Index (CESI), Harvey-Bradshaw Index (HBI) and Biological Markers in Small Bowel Crohn's Disease (SBCD)
Background: Small bowel Crohn's disease (SBCD) is a chronic relapsing disease, and clinical presentation can vary considerably. Patients are frequently assessed by capsule endoscopy (CE), which enables direct visualization of…
- Trial name
- NCT01555437
- Volunteers
- 58 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Crohn Disease
Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease
This research study will evaluate if specific blood, stool and MRI tests can tell the difference between bowel wall inflammation without scarring and bowel wall inflammation with scarring that can cause bowel blockages requiring…
- Trial name
- NCT04088773
- Testing
- blood biomarkers, stool biomarkers, MRI imaging
- Where
- 4 sites in United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati