Clinical trials: Smell Functions
Delayed Neurocognitive Recovery
Olfactory Function and Delayed Neurocognitive Recovery
To explore whether odor enrichment can reduce the risk of delayed neurocognitive recovery as an intervention strategy.
- Trial name
- NCT03441074
- Testing
- Odor Enrichment
- Where
- China
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Breast Cancer, Chemotherapy-related Cognitive Impairment
Evaluation of Cognitive Education Activities in Breast Cancer Patients Receiving Chemotherapy
Breast cancer is one of the most common cancer types worldwide and accounts for approximately 31% of all cancers in women. The global incidence of breast cancer is increasing, making it a significant public health problem.
- Trial name
- NCT07570251
- Testing
- Cognitive Function Training Activities
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Saglik Bilimleri Universitesi
Glaucoma
Assessment of the Ability to Distinguish Odors in Glaucoma Patients
Glaucoma is one of the leading causes of blindness worldwide. The key feature of glaucoma is damage to the optic nerve head with loss of retinal ganglion cells and local tissue remodeling.
- Trial name
- NCT00304824
- Volunteers
- 30 people
- Sponsor
- University Hospital, Basel, Switzerland
Mild Birth Asphyxia, Moderate Birth Asphyxia
Olfactory Testing in Perinatal Asphyxia: Enhancing Risk Assessment
Neonatal asphyxia remains a leading cause of neurodevelopmental disabilities despite advancements in perinatal care. Hypoxic-ischemic encephalopathy (HIE), a severe outcome of asphyxia, impacts 1-3 infants per 1,000 live births…
- Trial name
- MEMOBRAIN (NCT06744244)
- Testing
- Olfactory Testing, Heart rate (HR), Heart Rate Variability (HRV), Respiratory Rate (RR), peripheral oxygen saturation (SpO2), Video-EEG
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Parma
Parkinson's Disease
A Study Assessing Change in Sense of Smell After Rasagiline Use in Parkinson's Patients
A decrease or loss of the sense of smell is very common in patients with Parkinson's Disease even in the earliest stages of the disease.
- Trial name
- PD-SOAR (NCT01007630)
- Testing
- Rasagiline
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- The Parkinson's Institute
Frailty, Perioperative/Postoperative Complications
Correlation of Preoperative Olfactory Identification Function With Frailty and Postoperative Complications and Mortality
The aim of this research project is to evaluate whether olfactory identification impairment is a reliable predictor of preoperative frailty and of postoperative complications and mortality in a population of older patients…
- Conditions
- Frailty, Perioperative/Postoperative Complications, Olfactory Disorder
- Trial name
- POOF (NCT04700891)
- Testing
- Olfactory identification test, Edmonton Frail Scale, Handgrip strength
- Where
- Belgium
- Volunteers
- 167 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Multiple Sclerosis
Olfactory and Trigeminal Functions in Patients With Multiple Sclerosis: Case-control Study
The sensation of smell is influenced by the somatosensory and chemesthetic sensati¬ons of the nose: for example, the cooling sensation of menthol or the prickle of carbon dioxide from carbonated drinks.
- Trial name
- NCT06020937
- Testing
- TDI, Trigeminal Test, Cognitive Evaluation by Montreal Cognitive Assessment
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Catania
Cardiovascular Disease, Diabetes
Taste Perception and Chronic Disease Risk
The purpose of the Taste Perception Study is to assess variations in the ability to taste and perceive sensations from various stimuli in younger (18-49 years) and older (50-85 years) volunteers.
- Conditions
- Cardiovascular Disease, Diabetes, Obesity, Metabolic Syndrome
- Trial name
- NCT01023906
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tufts University
Respiratory Tract Infection, Smell Disorder
Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)
Background: Loss of the sense of smell can seriously affect a person's quality of life. The ability to smell can be damaged by many factors, including illnesses, injuries, and exposure to toxic chemicals.
- Conditions
- Respiratory Tract Infection, Smell Disorder, Influenza, Rhinosinusitis
- Trial name
- NCT07149428
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Coronavirus Disease 2019
Olfactory and Neurosensory Rehabilitation in COVID-19-related Olfactory Dysfunction
A combination of oral vitamin A (VitA) and intense aromatic chemosensory smell training (ST) by pulse aromatic stimulation will expedite the neurosensory recovery of olfaction in patients suffering from prolonged COVID-19-related…
- Trial name
- NCT04900415
- Testing
- Vitamin A, Electronic portable aromatic rehabilitation (EPAR) diffuser
- Where
- 2 sites in Hong Kong
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ivan FN Hung MD
Human Olfactory Amygdala Function
Characterization of Human Olfactory Amygdala Subregions Exp3
We aim to better understand the functions of the subregions of the human amygdala that receive direct projections from the olfactory bulb
- Trial name
- NCT07060651
- Testing
- Present odors to participants while recording and stimulating brain activity
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northwestern University