Clinical trials: Smokeless Tobacco Use
Smokeless Tobacco
Influence of Authorized Smokeless Tobacco Product Modified Risk Claims II: Laboratory Assessment of Sensory and Subjective Effects
This study seeks to measure the effects of smokeless tobacco product risk messages on sensory experiences and future intentions to use.
- Trial name
- NCT07107139
- Testing
- Copenhagen group, Snus group
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Tobacco Use
Nicotine Pharmacokinetics and Subjective Effects of Oral Nicotine Products Relative to Smokeless Tobacco in Adult Users
The purpose of this study was to obtain information on nicotine exposure following the use of five oral tobacco-derived nicotine (OTDN) products relative to subjects' own brand moist smokeless tobacco (OBMST) product in adult…
- Trial name
- NCT06691386
- Testing
- Test Product A, Test Product B, Test Product C
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Altria Client Services LLC
Smokeless Tobacco
Human Laboratory Study of Smokeless Tobacco Products
With the advent of restrictions on public smoking, the tobacco industry has introduced a variety of novel smokeless tobacco products (NSTP) to allow continued tobacco use.
- Trial name
- NCT01100216
- Testing
- Nicotine Lozenge, Stonewall Dissolvable Tobacco Pieces, Camel Snus Frost
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Use Disorder
Efficacy of Varenicline for Smokeless Tobacco Use in India
This study, based in India, is testing the efficacy of varenicline to help smokeless tobacco users with cessation efforts.
- Trial name
- NCT01098305
- Testing
- Varenicline, Counseling
- Where
- India
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tobacco Use Disorder
Effectiveness of a Web-Assisted Quitline for Smokeless Tobacco Users
The purpose of this record is to test whether (a) participants who receive a Web-based smokeless tobacco cessation intervention will be more likely to be abstinent than participants who do not receive this intervention, and (b)…
- Trial name
- NCT00820495
- Testing
- Web + Phone, Web Only, Phone Only
- Where
- 2 sites in United States
- Volunteers
- 1,683 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Tobacco Use Disorder
Comparison Across Treatment Conditions to Reduce Smokeless Tobacco Use
Smokeless tobacco (ST), which includes both chewing tobacco and snuff, has health risks associated with its use. While treatment programs that focus on stopping tobacco use may be effective, past research has shown that…
- Trial name
- NCT00218296
- Testing
- Usual Care Group, Reduction Group
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Product Beliefs and Use
Effects of FDA Authorized Smokeless Tobacco Claims Among US Adults Who Smoke Cigarettes
This study will be an online survey experiment conducted with adults who smoke cigarettes (ages 21+) to examine their reactions to modified risk advertising claims authorized by the Food \& Drug Administration (FDA) for two…
- Trial name
- NCT06927700
- Testing
- Modified Risk Claim Type - None, Product Brand - General Snus, Product Brand - Copenhagen
- Where
- United States
- Volunteers
- 1,257 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Smokeless Tobacco Cessation
Testing ANSOS for Efficacy in Multi-Tribal Urban Communities
This is a wait-list control trial to test for efficacy of the All Nations Snuff Out Smokeless (ANSOS) recreational tobacco cessation program in multi-tribal American Indian (AI) communities.
- Trial name
- NCT06566703
- Testing
- All Nations Snuff Out Smokeless, Healthy Living
- Where
- United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Lehigh University
Smokeless Tobacco Cessation
Improvement in Knowledge and Perception About Hazards of Smokeless Tobacco
Oral cancer is a serious and growing problem in many parts of the globe. Oral cancer is the eighth most common cancer worldwide.The annual estimated incidence is around 275,000 for oral and 130,300 for pharyngeal cancers…
- Trial name
- NCT03418506
- Testing
- SMOKELESS TOBACCO AWARENESS PROGRAM
- Where
- Pakistan
- Volunteers
- 1,327 people
- Sponsor
- Aga Khan University
Tobacco Use Disorder
Using Smokeless Tobacco Products With Lower Nicotine Levels to Reduce Negative Effects of Smokeless Tobacco Use
Though spit tobacco is smokeless, it still affects the cardiovascular system and may be associated with heart disease, stroke, and high blood pressure.
- Trial name
- Brandswitch (NCT00218244)
- Testing
- Lower Nicotine Smokeless Tobacco Product, Behavioral Counseling
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cardiovascular Disease, Cigarette Smoking
Cardiovascular Disease Biomarkers in Smokers and Moist Snuff Consumers
This cross-sectional study was primarily a cardiovascular disease (CVD) study designed a) to compare selected CVD biomarker data between subjects who were long-term consumers of cigarettes or moist snuff and non-consumers of…
- Trial name
- NCT01692353
- Testing
- Subject's usual brand (UB) tobacco product
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- R.J. Reynolds Tobacco Company
Tobacco Use
Pilot Randomised Controlled Trial of ToQuit Intervention in India
Tobacco use is associated with high mortality, and a range of morbidities including cancer, and lung and cardiovascular diseases.
- Trial name
- ToQuit (NCT04782453)
- Testing
- ToQuit, a technology delivered tobacco cessation intervention, Tobacco quitting helplines
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sangath
Tobacco Use
CSD190102: A Study to Assess Nicotine Pharmacokinetic Parameters After Use of Two Smokeless Tobacco Products
The purpose of this study is to compare plasma nicotine uptake in adult snus consumers after using investigational snus products (A19010-R and B19010-O).
- Trial name
- NCT03993782
- Testing
- A19010-R, B19010-O
- Where
- 6 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Tobacco Use
CSD190103: A Study to Assess Nicotine Pharmacokinetic Parameters After Use of Two Smokeless Tobacco Products
The purpose of this study is to compare plasma nicotine uptake in adult snus consumers after using investigational snus products (A19010-W and B19010-F).
- Trial name
- NCT03993795
- Testing
- A19010-W, B19010-F
- Where
- 6 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Smoking, Smoking, Cigarette
The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study
Mobile health (mHealth) will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers.
- Conditions
- Smoking, Smoking, Cigarette, Smoking, Tobacco, Betel Chewer's Mucosa
- Trial name
- NCT06535867
- Testing
- mHealth
- Where
- United States
- Volunteers
- 5,122 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cigarette Smoking
Controlled Study of the Ability of a Smokefree Tobacco Product to Increase the Quit Rate Among Cigarette Smokers
The study aims to assess if use of a low-nitrosamine, Swedish, smokefree tobacco product for oral use ("snus") can increase the quit rate among cigarette smokers who wish to stop smoking
- Trial name
- NCT00843622
- Testing
- Low-nitrosamine smokefree tobacco product for oral use
- Where
- 4 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Swedish Match AB
Adverse Effect of Other Agents Primarily Affecting the Cardiovascular System, Initial Encounter
Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products
The overarching goal of this project is to develop a panel of cardiovascular risk biomarkers that can detect differences in the cardiovascular safety of various tobacco products, whether conventional, new or emerging, in order to…
- Trial name
- NCT01964807
- Testing
- Cigarette, NIDA test type with 16.6 mg nicotine, Cigarette, NIDA test type with <0.45 mg nicotine, Electronic cigarette with 18 mg/ml nicotine
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smokeless Tobacco Cessation
Nicotine Lozenges and Assisted Self-help for Smokeless Tobacco Cessation
This research study will determine if using a combination of 4-mg nicotine lozenges, self-help materials, and/or telephone tobacco cessation counseling will help smokeless tobacco users stop using tobacco.
- Trial name
- LASH (NCT01341938)
- Testing
- Commit® nicotine lozenges (4 mg) & self-help materials, Commit® nicotine lozenges (4 mg) & phone counseling & self-help materials, Phone counseling & self-help materials
- Where
- United States
- Volunteers
- 1,067 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Smokeless Tobacco, Nicotine Dependence
Treating Smokeless Tobacco Use in Rural Veterans
This is a pilot study designed in an effort to develop and improve access to effective treatments for tobacco use in rural Veterans using a tailored intervention approach.
- Trial name
- NCT02994082
- Testing
- Tailored behavioral intervention, Behavioral activation for elevated depressive symptoms, Post-cessation weight gain management
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Mark Vander Weg
Smokeless Tobacco Use
A Pilot Study Evaluating Nicotine Lozenges and Self Help
The investigators are hypothesizing that by offering both self-help materials and mailed nicotine lozenges we will be able to help increase tobacco abstinence rates among ST users, as well as decrease tobacco withdrawal.
- Trial name
- NCT00888459
- Testing
- nicotine replacement therapy
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic