Clinical trials: Smokeless Tobacco Use
Tobacco Use Cessation
Study Evaluating The Efficacy Of Varenicline In Cessation Of Oral Smokeless Tobacco Use
The primary goal of this study is to compare efficacy of varenicline to placebo for cessation of use of smokeless tobacco.
- Trial name
- NCT00717093
- Testing
- Varenicline Tartrate
- Where
- 16 sites in Norway, Sweden
- Volunteers
- 432 people
- Sponsor
- Pfizer
Smokeless Tobacco Use
Nicotine Lozenges for Treatment of Smokeless Tobacco Addiction
This study will be a randomized, blinded, placebo-controlled two-group clinical trial. The independent variable is treatment assignment (active 4-mg nicotine lozenge vs.
- Trial name
- NCT00392379
- Testing
- Nicotine Lozenges
- Where
- 2 sites in United States
- Volunteers
- 270 people
- Sponsor
- Mayo Clinic
Smokeless Tobacco Cessation
Smokeless Tobacco Cessation Intervention for Firefighters
The investigators are asking professional firefighters across North Carolina to take part in focus groups to discuss the specific needs of firefighters in smokeless tobacco cessation.
- Trial name
- NCT05111041
- Testing
- #EnufSnuff.TXT- First Responder, Enough Snuff Intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duke University
Nicotine Dependence
Health Effects of SLT, Cigarette Smoking, and New Tobacco Products
The use of smokeless tobacco (ST) as a substitute for cigarette smoking has been suggested since it is considered by some to be a less harmful tobacco product (Russell, Jarvis and Feyerabend, 1980; Russell et al, 1981; Rodu…
- Trial name
- ANTS3 (NCT00469079)
- Testing
- Nicotine gum and lozenge, Taboka, Camel Snus
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smokeless Tobacco Use
A Pilot Study Evaluating Nicotine Lozenges and Self Help
The investigators are hypothesizing that by offering both self-help materials and mailed nicotine lozenges we will be able to help increase tobacco abstinence rates among ST users, as well as decrease tobacco withdrawal.
- Trial name
- NCT00888459
- Testing
- nicotine replacement therapy
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Tobacco Use Disorder
Efficacy of Varenicline for Smokeless Tobacco Use in India
This study, based in India, is testing the efficacy of varenicline to help smokeless tobacco users with cessation efforts.
- Trial name
- NCT01098305
- Testing
- Varenicline, Counseling
- Where
- India
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tobacco Dependence
Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction
Smokeless tobacco (ST) is a known human carcinogen. Long-term ST use is known to increase the risk for oropharyngeal cancer. Extant literature on cigarette smokers suggests that smoking reduction increases smoking abstinence…
- Trial name
- NCT01018394
- Testing
- nicotine lozenges, tobacco-free snuff
- Where
- 2 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Nicotine Dependence
Varenicline for the Treatment of Smokeless Tobacco
Varenicline (Chantix™, Pfizer) is a novel selective nicotinic receptor partial agonist with specificity for the α4β2 nicotine acetylcholine receptor that has demonstrated remarkable efficacy for increasing long-term tobacco…
- Trial name
- CHANCHEW (NCT00813917)
- Testing
- varenicline
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Smokeless Tobacco Cessation
A Text-based Reduction Intervention for Smokeless Tobacco Cessation
Participants will be randomly assigned (like the flip of a coin) to one of the two groups after completing the baseline survey. Participants have a 50% of being in either the #EnufSnuff.TXT intervention group or the Enough Snuff…
- Trial name
- NCT04315506
- Testing
- #EnufSnuff.TXT Intervention, Enough Snuff Intervention
- Where
- United States
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- Duke University
Smokeless Tobacco Use, Tobacco Dependence
Novel Determinants and Measures of Smokeless Tobacco Use: Study 1
The extent of toxicity varies considerably across different brands of smokeless tobacco (ST) products and data suggest that greater toxicity may result in greater health risks.
- Trial name
- NCT01067586
- Where
- 3 sites in United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Use Disorder
Comparison Across Treatment Conditions to Reduce Smokeless Tobacco Use
Smokeless tobacco (ST), which includes both chewing tobacco and snuff, has health risks associated with its use. While treatment programs that focus on stopping tobacco use may be effective, past research has shown that…
- Trial name
- NCT00218296
- Testing
- Usual Care Group, Reduction Group
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smokeless Tobacco Use
Highdose Nicotine Patch Therapy for Smokeless Tobacco Use
Smokeless tobacco use ("chewing") is associated with negative health effects. To date, no medications have been shown to help chewers quit long-term.
- Trial name
- NCT00939029
- Testing
- nicotine replacement therapy (nicotine patches)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Tobacco Product Beliefs and Use
Effects of FDA Authorized Smokeless Tobacco Claims Among US Adults Who Smoke Cigarettes
This study will be an online survey experiment conducted with adults who smoke cigarettes (ages 21+) to examine their reactions to modified risk advertising claims authorized by the Food \& Drug Administration (FDA) for two…
- Trial name
- NCT06927700
- Testing
- Modified Risk Claim Type - None, Product Brand - General Snus, Product Brand - Copenhagen
- Where
- United States
- Volunteers
- 1,257 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Cigarette Smoking
Controlled Study of the Ability of a Smokefree Tobacco Product to Increase the Quit Rate Among Cigarette Smokers
The study aims to assess if use of a low-nitrosamine, Swedish, smokefree tobacco product for oral use ("snus") can increase the quit rate among cigarette smokers who wish to stop smoking
- Trial name
- NCT00843622
- Testing
- Low-nitrosamine smokefree tobacco product for oral use
- Where
- 4 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Swedish Match AB