Clinical trials: Smoker
Smokers, Vaping
Persistence of Oral DNA Adducts in Smokers and Vapers
This study aims to better understand what damage caused to oral cells from smoking and vaping might be important in the formation of oral cancers.
- Conditions
- Smokers, Vaping, Healthy Volunteers
- Trial name
- NCT06983392
- Testing
- Abstain from smoking/vaping
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking, Rehabilitation; Tobacco Use
Pulmonary Rehabilitation and Smoking
Pulmonary rehabilitation (PR) is known to reduce dyspnea, increase exercise capacity, reduce psychological symptoms and improve quality of life in COPD patients. Some patients continue to smoke despite their illness.
- Trial name
- NCT03671187
- Testing
- Exercise
- Volunteers
- 31 people
- Sponsor
- Izmir Katip Celebi University
Lung Cancer
Clinical Trial of Lung Cancer Chemoprevention With Sulforaphane in Former Smokers
This research study involves taking an experimental anti-cancer dietary supplement called Sulforaphane (SF) or a placebo (product without any supplement content) over a period of twelve months in order to determine if it is a…
- Trial name
- NCT03232138
- Testing
- Sulforaphane
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Jian-Min Yuan, MD
Tobacco Cessation
Intervention Study to Increase Smoking Cessation Rates Among Public Housing Residents
The purpose of this study is to determine whether public housing residents trained in Tobacco Cessation and Motivational Interviewing Techniques to become Tobacco Treatment Advocates(TTA) will be effective in increasing the quit…
- Trial name
- NCT01651611
- Testing
- Motivational interviewing, Smoking cessation counseling, Navigation to smoking cessation resources
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Boston University
AKT
Analysis of Tissues From Patients in Trial of Myo-Inositol to Prevent Lung Cancer
This study will examine tissue specimens from patients participating in a trial of high-dose myo-inositol to prevent lung cancer.
- Trial name
- NCT00342836
- Testing
- Akt levels
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Healthy Subject, Tobacco Use Disorder
Effect of Black Raspberry Phytochemicals on Oral Microbiome in Current Smokers and Non-smokers
This randomized clinical trial studies the effects of black raspberry compounds (phytochemicals) on the bacteria in the mouth (oral microbiome) of current smokers and non-smokers.
- Trial name
- NCT02439255
- Testing
- Laboratory Biomarker Analysis, Phytochemical, Screening Questionnaire Administration
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Smokers
Study to Evaluate the Efficacy, Safety, Tolerability and Immunogenicity of 100µg NIC002 Vaccine in Cigarette Smokers Who Are Motivated to Quit Smoking.
This study is designed to determine the efficacy of high nicotine-specific antibody titers in smoking cessation.
- Trial name
- NCT00736047
- Testing
- NIC002
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Novartis
Oxidative Stress, Inflammation
PsP Ganoderma Lucidum Supplementation and Biomarker Changes in Smokers
The goal of this randomized controlled clinical trial is to evaluate whether polysaccharide peptide (PsP) supplementation from Ganoderma lucidum can modulate biomarkers of oxidative stress, inflammation, nicotine exposure, and…
- Conditions
- Oxidative Stress, Inflammation, Cigarette Smoking
- Trial name
- PSPGL (NCT07316400)
- Testing
- PsP
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Brawijaya
Schizophrenia, Nicotine Addiction
Effects of rTMS on Cigarette Smoking and Cognition in Schizophrenia
Cigarette smoking rates are extremely high in persons with schizophrenia and this increases the risk of disease and death due to tobacco-related disorders.
- Trial name
- rTMSsmokelab (NCT01523730)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Pregnancy Related, Tobacco Smoking
Effects of Prenatal Tobacco Smoke Exposure on Lung Function and Respiratory Epithelium Functionality in Newborns
Despite public campaigns to prevent cigarette smoking, it's about 20% of women who keep on smoking during pregnancy, exposing their fetus to prenatal tobacco adverse effects.
- Conditions
- Pregnancy Related, Tobacco Smoking, Lung Smokers, Newborn
- Trial name
- NCT03047967
- Testing
- lung function tests, Nasal brushing
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Cigarette Smoking
Effects of Deep Breathing Exercise on Pulmonary Function, Perceived Stress and Physical Fitness Among Healthy Smokers
Effects of deep breathing exercise on pulmonary function, perceived stress and physical fitness among healthy smokers.
- Trial name
- NCT06032793
- Testing
- Breathing exercises
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Inflammation, Thrombosis
Investigation on the Effect of Smoking on the Expression of Pro- and Anti-thrombotic, Anti-oxidative, and Inflammatory Markers in Humans
Investigation on the effect of smoking on thrombus formation in humans. The expression of pro- and anti-thrombotic, anti-oxidative, and inflammatory markers will be assessed in 25-50 year old healthy smokers and non-smokers.
- Conditions
- Inflammation, Thrombosis, Smoking
- Trial name
- NCT02198937
- Testing
- Blood sample
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Tobacco Use Disorder
Maintenance Treatment for Abstinent Smokers
The purpose of this study is to determine the efficacy and cost-effectiveness of long-term pharmacotherapy (using Zyban and/or nicotine replacement) for reducing the relapse rate associated with stopping smoking.
- Trial name
- NCT00063323
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 589 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Current Smoker, Tobacco Smoking
Project MARS: Mobile-Assistance for Regulating Smoking
This study aims to investigate approaches to capitalize on states of vulnerability and receptivity to deliver real-time self-regulation prompts among smokers.
- Trial name
- MARS (NCT04376489)
- Testing
- Messages recommending low effort strategies (participants experiencing negative affect & cigarettes are available), Messages recommending low effort strategies (participants not experiencing negative affect & cigarettes are available), Messages recommending low effort strategies (participants experiencing negative affect & cigarettes are not available)
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Utah
Asthma
Mechanism(s) of Airflow Limitation During Exacerbation of Asthma
The purpose of this study is to evaluate the site and mechanisms responsible for expiratory airflow limitation in chronic, treated, non-smoking, stable asthmatics with moderate to severe persistent expiratory airflow obstruction.
- Trial name
- NCT01225913
- Testing
- fluticasone/salmeterol in all asthmatics, budesonide/formoterol or fluticasone/salmeterol in all asthmatics
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Gelb, Arthur F., M.D.
Lung Cancer
LDCT Screening in Non-smokers in Taiwan
This study utilizes the low dose computed tomography(LDCT) to detect the occurrence of early lung cancer among non-smokers in Taiwan.
- Trial name
- NCT02611570
- Testing
- LDCT
- Where
- 17 sites in Taiwan
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Academia Sinica, Taiwan
Tobacco Use Disorder
Varenicline or Nicotine Patch in Promoting Smoking Cessation Among Current Smokers
This pilot clinical trial studies varenicline or nicotine patch in promoting smoking cessation among current smokers. Varenicline or nicotine patch may help people stop smoking
- Trial name
- NCT01771627
- Testing
- varenicline, nicotine patch
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Roswell Park Cancer Institute
Lung Carcinoma
MUC1 Vaccine in Preventing Lung Cancer in Current and Former Smokers at High Risk for Lung Cancer
This pilot phase I trial studies the side effects and how well MUC1 peptide-Poly-ICLC vaccine works in preventing lung cancer in current and former smokers at high risk for lung cancer.
- Trial name
- NCT03300817
- Testing
- Laboratory Biomarker Analysis, MUC1 Peptide-Poly-ICLC Vaccine
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)
Lung Cancer
Oltipraz in the Prevention of Lung Cancer in People Who Smoke
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development of cancer. PURPOSE: Randomized phase I trial to study the effectiveness of oltipraz in preventing lung cancer in people who smoke.
- Trial name
- NCT00006457
- Testing
- oltipraz
- Where
- 2 sites in United States
- Sponsor
- Northwestern University
Smoking Cessation
Mobile Smoking Treatment for Spanish-speaking Latinx Smokers
The specific aims of the project are to develop and test a Spanish language, mobile app for smoking cessation called Impacto.
- Trial name
- NCT04417075
- Testing
- Impacto (Mobile App), Dejar de Fumar Asistente (Mobile App)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Houston
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