Clinical trials: Smoking, Tobacco
Sleep, Lung Diseases
Predicting Sleep, Smoking, and Lung Health Disparities in African American Adults
This 5-year prospective, observational study will: (1) determine the individual, social, and environmental predictors of sleep duration, quality, latency, efficiency, timing and regularity in African American smokers, (2)…
- Conditions
- Sleep, Lung Diseases, Smoking
- Trial name
- NCT03534076
- Testing
- Cohort Observational study
- Where
- United States
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- Temple University
Smoking, Cancer
Parent Willingness to Participate in Tobacco Trials in the Pediatric Clinical Setting
Little is known about what factors influence parental decisions to participate or to decline participation in tobacco trials offered in the pediatric clinical setting.
- Conditions
- Smoking, Cancer, Sickle Cell Disease
- Trial name
- NCT01673243
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- St. Jude Children's Research Hospital
Smoking Cessation
Behavioral and Enhanced Perinatal Intervention for Cessation (B-EPIC): Reducing Tobacco Use Among Opioid Addicted Women
This study tests an intervention for tobacco cessation (named B-EPIC) in an established community medication assisted treatment (MAT) clinic for pregnant and postpartum women with opioid dependence.
- Trial name
- B-EPIC (NCT03796208)
- Testing
- Behavioral and Enhanced Perinatal Intervention for Cessation (B-EPIC), Treatment As Usual
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- Kristin Ashford
E-cigarette, Alcohol
Flavored Ready-to-Drink Alcohol Restriction in Young Adults: Behavioral and Biomarker Outcomes
This pilot randomized behavioral study evaluates the feasibility, adherence, and acceptability of an intervention to restrict flavored ready-to-drink (RTD) alcoholic beverages among young adults who regularly use both alcohol and…
- Trial name
- NCT07840625
- Testing
- Flavored Ready-to-Drink alcoholic beverage use restriction
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Smoking Cessation
Health Communications for Adults Smoking Nondaily
The goal of this study is to develop smoking health risk messaging targeted to adults who smoke some days, but not smoke every day (nondaily).
- Trial name
- NCT07296848
- Testing
- Targeted Smoking Messages
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Bethany Shorey Fennell, PhD
Chronic Pain, Smoking, Cigarette
Low Nicotine Cigarettes, Smoking, and Chronic Pain
The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes on experiences with craving, withdrawal, and pain among individuals…
- Trial name
- VLNCPain (NCT05032755)
- Testing
- SPECTRUM NRC 102/103 investigational cigarettes, SPECTRUM NRC 600/601 investigational cigarettes
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Nicotine Addiction
Investigation of Cycloserine as a Smoking Cessation Treatment
Psychosocial treatments for drug abuse benefit some patients (Rawson et al 2004), but there is an urgent need for new treatment approaches that can improve treatment outcomes.
- Trial name
- NCT01062932
- Testing
- Cycloserine
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Baylor College of Medicine
Tobacco Use, Smoking Cessation
The Effect of Motivational Interviewing on Smoking Behavior Among Nursing Students
Smoking is one of the leading preventable public health problems worldwide, particularly among young adults who are at increased risk of nicotine dependence.
- Trial name
- NCT07758998
- Testing
- Transtheoretical Model-Based Motivational Interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Meral Feratoğlu Research
Smoking Cessation, Vaping Cessation
Safety Study of Cytisinicline in Adult Combustible and/or E-cigarette Smokers
Safety assessment of long-term 3 mg cytisinicline three times daily (TID) exposure for 52 weeks is the main purpose of this study, conducted in the United States.
- Trial name
- ORCA-OL (NCT06435221)
- Testing
- Cytisinicline
- Where
- 29 sites in United States
- Volunteers
- 479 people
- Sponsor
- Achieve Life Sciences
ADHD
Prevention of Cigarette Smoking in Attention Deficit Hyperactivity Disorder (ADHD) Youth With Concerta
This study will consist of a six-week open-label treatment period with an extended duration methylphenidate (OROS MPH) followed by subsequent monthly visits for 24 months in a large sample of youths aged 12-17 who meet Diagnostic…
- Trial name
- NCT00181714
- Testing
- methylphenidate HCl (Concerta)
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Massachusetts General Hospital
Nicotine Dependence, Nicotine Addiction
Effectiveness of N-Acetylcysteine (NAC) in Motivational Enhancement Therapy for Nicotine Addiction
The goal of this clinical trial is to determine the effectiveness of the combination of n-acetylcysteine and motivational enhancement therapy on laboratory improvement in the form of changes in blood nicotine, radiological…
- Trial name
- NCT05903014
- Testing
- n-acetylcysteine, Motivational Enhancement Therapy
- Where
- Indonesia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Smoking Cessation
Aversive Therapy for Smoking Cessation
The purpose of this research study is to test a new way to help people quit smoking. The PI will test acceptability and feasibility of a new device called Pavlok wearable wrist band.
- Trial name
- NCT03450148
- Testing
- Pavlok wristband with electric stimulus, Pavlok wristband without electric stimulus
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Alabama at Birmingham
Smoking, Tobacco Use
BAT3221032: A Study to Evaluate the Effects of Switching From Cigarette Smoking to Using One of Five Variants of a Heated Tobacco Product on Biomarkers of Exposure and Biomarkers of Potential Harm in Healthy Subjects
This is a randomized, controlled, multi-center, open-label, 8-cohort parallel group study to assess changes in select biomarkers of exposure (BoE) and biomarkers of potential harm (BoPH) in generally healthy smokers switching to…
- Conditions
- Smoking, Tobacco Use, Tobacco Smoking
- Trial name
- NCT05142436
- Testing
- Product A: Non-Combusted Cigarette Variant 42001402 and product use Mode B, Product B: Non-Combusted Cigarette Variant 42001399 and product use Mode B, Product C: Non-Combusted Cigarette Variant 42001401 and product use Mode B
- Where
- 18 sites in United States
- Volunteers
- 806 people, healthy volunteers welcome
- Sponsor
- British American Tobacco (Investments) Limited
Smoking Cessation, Smoking Abstinence
Breathe 2 Project 3: Comprehensive Chronic Care
This study will evaluate Comprehensive Chronic Care (CCC), a healthcare treatment approach designed to increase smoking treatment engagement and abstinence among primary care patients who smoke.
- Trial name
- NCT05382221
- Testing
- Comprehensive Chronic Care, Standard Care
- Where
- 2 sites in United States
- Volunteers
- 979 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Smoking Cessation, Emergency Department Visit
Acute Respiratory Disease as a Fulcrum Point to Quit Smoking: Evaluation of an ED-based Intervention
This study aims to evaluate smoking cessation success rates using the Fagerström Test for Nicotine Dependence (FTND) in smoking cessation treatment.
- Conditions
- Smoking Cessation, Emergency Department Visit, Acute Respiratory Infections (ARIs)
- Trial name
- Intervention (NCT06923852)
- Testing
- Smoking cessation support that World Health Organization (WHO) 5A model (Ask, Advise, Assess, Assist, Arrange).
- Volunteers
- 288 people
- Sponsor
- Seda Oğuz
Smoking, Tobacco Smoking
Effect of Packaging on Smoking Perceptions and Behavior
The investigators are addressing two critical areas identified by the FDA: the impact of cigarette packaging and labeling on consumer perceptions and on smoking behavior; and the effectiveness of graphic warning labels on…
- Trial name
- CASA (NCT02676193)
- Testing
- Effect of Packaging on Smoking Perceptions and Behavior
- Where
- United States
- Volunteers
- 359 people
- Sponsor
- University of California, San Diego
Tobacco Smoking
Developing Genetic Education for Smoking Cessation
This study will test the effects of an educational program about genetics and smoking on smokers' thoughts, feelings, and behaviors before and after participating in smoking cessation treatment.
- Trial name
- NCT01186016
- Testing
- Genetic Education Session, Nutrition Education Session
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Healthy Volunteers
Safety and Pharmacokinetics of Smoked Cannabis in Healthy Patients
No actual human data for pharmacokinetics, metabolism, safety, pharmacodynamics, nor efficacy parameters are available for inhaled medical cannabis.
- Trial name
- NCT04314804
- Testing
- PPP001
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tetra Bio-Pharma
ADHD, Smoking
Smoking Cessation for Adults With Attention Deficit Hyperactivity Disorder (ADHD)
The objective of this study is to evaluate whether Osmotic-Release Methylphenidate (OROS MPH), relative to placebo, increases the effectiveness of standard smoking treatment (i.e., nicotine patch and individual smoking cessation…
- Trial name
- NCT00253747
- Testing
- Osmotic-Release Methylphenidate
- Where
- 6 sites in United States
- Volunteers
- 255 people
- Sponsor
- University of Cincinnati
Anxiety Disorders, Anxiety
Personalized Feedback for Smokers With Elevated Anxiety Sensitivity
This project will develop and refine a computer-delivered integrated Personalized Feedback Intervention (PFI) that directly addresses smoking and anxiety sensitivity (AS).
- Conditions
- Anxiety Disorders, Anxiety, Tobacco Dependence, Smoking, Cigarette
- Trial name
- NCT03382093
- Testing
- Personalized Feedback Intervention, Smoking Information Control
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Houston
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