Clinical trials: Smoking, Tobacco
Obesity, Smoking Cessation
Trial for Harm Reduction With Incentives & Vaping E-cigarettes
The purpose of this study is to provide preliminary information on the effect of electronic nicotine delivery systems (ENDS) provisions and contingent incentives (CI) on smoking in individuals with overweight/obesity who smoke…
- Trial name
- THRIVE (NCT06111053)
- Testing
- ENDS, CI, No ENDS
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Brown University
Cardiovascular Diseases, Chronic Obstructive Pulmonary Diseases
The Efficacy and Safety of Electronic Cigarettes: a 5-year Follow-up Study
The main aim of this multicentric 5-year follow-up study is to evaluate for the first time the long-term efficacy and safety (in terms of smoking-related serious diseases requiring hospitalization) of e-cigarette smoking…
- Conditions
- Cardiovascular Diseases, Chronic Obstructive Pulmonary Diseases, Cancer of the Lung, Cancer of the Bladder
- Trial name
- NCT01785537
- Where
- Italy
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Università degli Studi 'G. d'Annunzio' Chieti e Pescara
Smoker
Methods Project 4: Clinical Trial
Cigarette smokers who are eligible will enter a Camel Snus sampling phase. Smokers interested in continuing with the study after the sampling phase will undergo a 2 week baseline assessment phase and will then be randomized to…
- Trial name
- NCT01867242
- Testing
- Cigarettes, Snus
- Where
- 3 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cardiovascular Diseases, Heart Diseases
Fluoxetine as a Quit Smoking AID for Depression Prone
To test whether adding fluoxetine pharmacotherapy to behavioral cessation treatment improves the depression-prone smoker's ability to quit.
- Trial name
- NCT00113737
- Testing
- fluoxetine, cognitive behavioral therapy
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Periodontitis, Smoking Cessation
Effect of Nicotine Gingival Fibroblast Intoxication on the Response of Periodontal Treatment
Impact of nicotine gingival intoxication on the clinical outcomes after periodontitis non surgical treatment
- Conditions
- Periodontitis, Smoking Cessation, Tobacco Dependence
- Trial name
- ENIPT's (NCT07491627)
- Testing
- periodontal non-surgical treatment
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- University of Liege
Tobacco Smoking
Promoting Evidenced-Based Tobacco Smoking Cessation Treatment in Community Mental Health Clinics
This pilot study will examine whether an implementation intervention will improve delivery of evidence-based treatment for tobacco smoking cessation for patients in community mental health clinics.
- Trial name
- IMPACT (NCT04796961)
- Testing
- Implementation Intervention
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Smoking ( Cigarette)
Ecological Momentary Assessment of Smoking Triggers, Needs, and Cigarette Forgoing
This study will evaluate a smartphone-based program designed to support adults who smoke cigarettes. Participants will use the spark app to complete brief surveys during the day and a daily evening survey about their smoking…
- Trial name
- spark Forgo (NCT07852845)
- Testing
- Non-Adaptive Motivational EMI, Adaptive Motivational EMI
- Volunteers
- 45 people
- Sponsor
- University of South Carolina
Smoking Cessation, Early-Stage Cancer
Multi-Theory Model-Based AI Agent Intervention for Smoking Cessation in Early-Stage Cancer Patients
The goal of this clinical trial is to evaluate the effectiveness of a Multi-Theory Model (MTM)-based AI agent intervention for smoking cessation in early-stage cancer patients (clinical stage cTNM 0~II) who currently smoke.
- Conditions
- Smoking Cessation, Early-Stage Cancer, AI Agent
- Trial name
- NCT07827066
- Testing
- MTM-Based AI Agent for smoking cessation, Counseling
- Volunteers
- 156 people
- Sponsor
- Sun Yat-sen University
Nicotine Dependence
Pexacerfont to Reduce Stress-induced Tobacco Craving
Background: Stressful situations often cause tobacco cravings. These cravings can make it very difficult for smokers who are trying to quit. Research has shown that craving may involve hormone pathways in the brain.
- Trial name
- NCT01557556
- Sponsor
- National Institute on Drug Abuse (NIDA)
Veterans, Tobacco Use Disorder
Varenicline for Smoking Reduction in Veterans Not Ready To Quit
In order to reduce the prevalence of cigarette smoking among Veterans, it is vital that healthcare providers offer effective tobacco treatment to all Veterans who smoke, including those not ready to make a quit attempt.
- Conditions
- Veterans, Tobacco Use Disorder, Cigarette Smoking, Tobacco Dependence
- Trial name
- NCT06966362
- Testing
- Motivation-Phase Varenicline, Motivation-Phase Nicotine Mini-Lozenge, Cessation-Phase Combination Nicotine Replacement Therapy (NRT)
- Where
- 4 sites in United States
- Volunteers
- 400 people
- Sponsor
- VA Office of Research and Development
Cigarette Smoking
The Effect of Smoking on Thermoregulation
To the best of our knowledge, a possible relation between smoking and heat injuries or heat intolerance was never scientifically examined, although such a relation is logical according to the observations that smoking has a…
- Trial name
- NCT01596556
- Testing
- Nicotine, cigarette smoking
- Where
- Israel
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Nicotine Dependence, Smoking, Cigarette
Isradipine Enhancement of Virtual Reality Cue Exposure for Smoking Cessation
The proposed study represents a crucial and important stage in translating basic research to strategies for treating nicotine dependence.
- Conditions
- Nicotine Dependence, Smoking, Cigarette, Smoking Cessation, Smoking Behaviors
- Trial name
- NCT03083353
- Testing
- Isradipine, Cue Exposure
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
Tobacco Products, Smoking Behavior
Communicating About Nicotine Reduction in Cigarettes
The goal of this clinical trial is to learn how a messaging campaign about reduced nicotine cigarettes and policy, combined with the use of very low nicotine cigarettes (VLNCs), affects smoking behavior and attitudes among adult…
- Conditions
- Tobacco Products, Smoking Behavior, Cigarette Use
- Trial name
- NCT06787937
- Testing
- VLNC messages, Control message
- Where
- 2 sites in United States
- Volunteers
- 1,230 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Cigarette Smoking, Tobacco Use
Identify the Usefulness of In-person and Virtual Quit Smoking Programs
This study is a randomized community-based trial adapted to the needs of adults aged 21 years or older that is designed by an existing research partnership called Communities Engaged and Advocating for Smoke-free Environments…
- Trial name
- CEASE (NCT05181072)
- Testing
- Enhanced in-person peer-motivation smoking cessation, Virtual peer-motivation smoking cessation
- Where
- United States
- Volunteers
- 392 people
- Sponsor
- Morgan State University
Postpartum Smoking Relapse
Perinatal Attentional Retraining Intervention for Smoking for Minority Women
The proposed research intends to randomize 50 abstinent pregnant Black or Hispanic smokers to receive either the attentional retraining (AR) or control VP task.
- Trial name
- PARIS (NCT04114877)
- Testing
- Attentional retraining (AR), Visual probe (VP)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Yale University
Gingivitis
Angiogenesis in Periodontal Disease
Gum disease (gingivitis and periodontitis) is a common inflammatory condition affecting the tissues that support the teeth. Smoking is known to make gum disease worse and to affect blood vessel health in the gums.
- Trial name
- NCT07765251
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Inonu University
Anorexia, Obesity
Estimating the Short-term Effectiveness of Online Advertisements for Improving Health
Bing ads designed to encourage people to adopt healthier practices (e.g., stop smoking, become physically active, stop consuming harmful content) are shown using the advertising system, to test which ads are more effective as…
- Conditions
- Anorexia, Obesity, Smoking Cessation
- Trial name
- NCT03439553
- Testing
- Ads display with target websites, Ads display with control websites
- Where
- Israel
- Volunteers
- 2,000,000 people, healthy volunteers welcome
- Sponsor
- Microsoft Research
Smoking Cessation, Tobacco Use Cessation
Interactive Communication Technologies and Nicotine Replacement Therapy Sampling for Smokers
Brief advice combined with active referral to smoking cessation (SC) services increases quitting. We aim to strengthen the effect of combined intervention by using interactive communication technologies and nicotine replacement…
- Trial name
- NCT04001972
- Testing
- Brief advice (AWARD model), NRT-S, IM Apps and Chatbot
- Where
- Hong Kong
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Pregnancy Related, Tobacco Smoking
Effects of Prenatal Tobacco Smoke Exposure on Lung Function and Respiratory Epithelium Functionality in Newborns
Despite public campaigns to prevent cigarette smoking, it's about 20% of women who keep on smoking during pregnancy, exposing their fetus to prenatal tobacco adverse effects.
- Conditions
- Pregnancy Related, Tobacco Smoking, Lung Smokers, Newborn
- Trial name
- NCT03047967
- Testing
- lung function tests, Nasal brushing
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Smokers, Periodontal Status
Periodontal Health Among Cigarette, Electronic Cigarettes, and Narghile Smokers
This study compares the different effects of traditional cigarettes, e-cigarettes, and narghile on periodontal health among a sample of Al-Hawash Private University students.
- Trial name
- NCT07562295
- Testing
- Non-Interventional Study
- Where
- Syria
- Volunteers
- 90 people
- Sponsor
- Al-Hawash Private University
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