Clinical trials: Smoking, Tobacco
Nicotine Dependence
Bupropion Treatment for Youth Smoking Cessation
The purpose of this study is to 1) evaluate the safety and efficacy of two doses of bupropion SR (150mg/day and 300mg/day) when compared to placebo, as an aid to smoking cessation in adolescents and 2) to examine which factors…
- Trial name
- NCT00344695
- Testing
- bupropion SR
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arizona
Nicotine Dependence
Adaptive Pharmacotherapy for Smoking Cessation
The purpose of this study is to assess an "adaptive" approach to smoking cessation pharmacotherapy. The protocol is designed to compare adaptive vs.
- Trial name
- NCT02501265
- Testing
- Varenicline Standard Protocol, Nicotine Patch Standard Protocol, Varenicline Adaptive Protocol
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- Duke University
Tobacco Use Disorder, Tobacco Smoking
Brain Imaging in Tobacco Smokers During a Quit Attempt
The proposed study will help fill gaps in existing research by determining if nicotine-dependent cigarette smokers show changes in α7 nicotinic acetylcholine receptor (nAChR) availability when compared to matched historical…
- Trial name
- NCT04055467
- Testing
- [F18]-ASEM (3-(1,4-diazabicyclo[3.2.2]nonan-4-yl)-6-[18F]fluorodibenzo[b,d]thiophene 5,5-dioxide), Contingency Management
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Smoking
Evaluating the Acute Effects of Electronic Nicotine Delivery Devices Marketed to Smokers.
The study's aim is to develop a clinical model that can be used to measure the nicotine delivery and tobacco/nicotine abstinence-suppressing capability of electronic devices that are marketed as a means to deliver nicotine to…
- Trial name
- NCT00932295
- Testing
- OB, CROWN SEVEN, NJOY
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Smoking, Tobacco Product
Japanese Post-Market Cohort Study
The objectives and endpoints of this study were analyzed in the study population of adults eligible to purchase tobacco products.
- Trial name
- NCT03020667
- Where
- Japan
- Volunteers
- 1,124 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Asthma
Effects of Budesonide & Budesonide/Formoterol on Smoking Asthmatic Subjects
A reduced response to inhaled corticosteroids (ICS) has been reported in smoking compared to non-smoking asthmatic patients. However, the comparative response to other currently prescribed medications such as combination therapy…
- Trial name
- D5890L00013 (NCT00691951)
- Testing
- budesonide and budesonide/formoterol
- Where
- 2 sites in Canada
- Sponsor
- Laval University
Tobacco Use Disorder
5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder
This is a multi-site, double-blind, randomized clinical trial of the 5-HT2A receptor agonist psilocybin for smoking cessation. Four sites with experience in conducting psilocybin research will be involved in this trial: Johns…
- Trial name
- NCT05452772
- Testing
- Psilocybin, Niacin
- Where
- 3 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Smoking Cessation, Tobacco Smoking
App for Pregnancy Smoking Cessation With Peer Support
The objectives of this project are to develop, implement, and test the feasibility and effectiveness of an artificial intelligence adaptive mobile pregnancy tobacco cessation app-based intervention using deep tailoring and a…
- Trial name
- SFT (NCT05337722)
- Testing
- SFT 2.0, Active control
- Where
- Romania
- Volunteers
- 786 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Biomarker Feedback, Smoking Cessation
Clinical Response to Biomarker Documentation of Child Secondhand Smoke Exposure
1. To do formative work with healthcare providers, clinic staff and parents to develop a protocol for a clinic system to routinely collect blood from children at risk of SHS exposure conduct laboratory testing for tobacco…
- Conditions
- Biomarker Feedback, Smoking Cessation, Secondhand Smoke Exposure, Provider Behavior
- Trial name
- NCT01145729
- Testing
- Biomarker Feedback
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health (NIH)
Obesity, Smoking Cessation
Addressing Post Cessation Weight Gain
Some individuals smoke with the perception that smoking helps control body weight. Smokers gain an average of as much as 10 pounds in the months following smoking abstinence, with heavier and more-dependent smokers gaining more…
- Trial name
- NCT02412631
- Testing
- lorcaserin, Varenicline
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Smoking, Asthma
E-cigarettes for Harm Reduction in Adults With Asthma
Smoking is the main cause of preventable disease and death in the US and impacts respiratory illnesses including COPD and asthma.
- Conditions
- Smoking, Asthma, Electronic Cigarette Use, Cigarette Smoking
- Trial name
- SWAP (NCT05278065)
- Testing
- Nicotine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Brown University
Nicotine Dependence
Effects of Chantix on Relapse Prevention for Smoking Cessation
The goal of the proposed study is to validate an experimental paradigm to assess medication effects on smoking relapse following a brief (3-day) monitored period of smoking abstinence and a programmed cigarette lapse.
- Trial name
- NCT00948649
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking Cessation
CONNECT: Smoking Cessation and Lung Cancer Screening
This clinical trial studies the impact of CONNECT on biochemically confirmed smoking abstinence among diverse current smokers who are undergoing lung cancer screening.
- Trial name
- NCT04149249
- Testing
- Computer-Assisted Intervention Video Doctor, Computer-Assisted Intervention no Video Doctor
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Periodontal Disease, Diabete Mellitus
Oral Health and Systemic Diseases: Survey of General Practitioners
This cross-sectional observational study aims to assess the level of knowledge, clinical practices, and professional attitudes of General Practitioners (GPs) regarding oral health and its relationship with major systemic…
- Trial name
- NCT07604493
- Testing
- Questionnaire Survey
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Tobacco Use Cessation
mHealth Messaging to Motivate Quitline Use Quitting
The mHealth Messaging to Motivate Quitline Use and Quitting, or "M2Q2" study, is a collaborative research project for a mobile health intervention designed to motivate smoking cessation and encourage access to counseling.
- Trial name
- M2Q2 (NCT03567993)
- Testing
- Comparison, Intervention
- Where
- Vietnam
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Smoking Behaviors
Acute Effects of Cigarette Packaging and Charcoal Filtration on Perceptions, Use Behaviors, and Harm Exposure
This single laboratory session pilot study will examine the acute effects of cigarette filter type and packaging on initial product perceptions, use, and exposure.
- Trial name
- SKY Pilot (NCT05157048)
- Testing
- Charcoal-filtered cigarette, Non-charcoal filtered cigarette
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Healthy Participant
Different Modes of Universal Adhesive in Smokers and Non-Smokers
The aim of the study was to evaluate the influence of smoking on the clinical performance of a universal adhesive used with different application modes in non-carious cervical lesions.
- Trial name
- NCT04807465
- Testing
- G-Premio Bond in etch&rinse mode, G-Premio Bond in selective-etch mode, G-Premio Bond in self-etch mode
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Tobacco Dependence, Smoking Cessation
Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence
The addition of tDCS as an adjunct to pharmacotherapy is a novel approach but one that is grounded in a growing evidence-base.The primary objective of this research is to provide preliminary evidence of the effectiveness of tDCS…
- Conditions
- Tobacco Dependence, Smoking Cessation, Tobacco Smoking, Tobacco Use Disorder
- Trial name
- NCT03841292
- Testing
- Varenicline, Active tDCS
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Centre for Addiction and Mental Health
Smoking Cessation, Tobacco Dependence
Behavioral Therapy for Reduction in Smoking Craving
The objective of this pilot research is to investigate the effects of two behavioral smoking cessation programs on aspects of cue-induced cigarette craving, and to further investigate the neural bases of such effects.
- Trial name
- NCT00449293
- Testing
- standard cognitive behavioral therapy, Mindfulness Based Cognitive Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Smoking, Smoking Cessation
Message Testing in Older Adult Smokers
This study is examining different messages to motivate older smokers to quit smoking. Participants will be current smokers, between the ages of 50-80 years old, who do not have a history of cognitive impairment or dementia.
- Trial name
- NCT05471349
- Testing
- Flyer and video
- Where
- United States
- Volunteers
- 820 people
- Sponsor
- University of Wisconsin, Madison
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