Clinical trials: Smoking, Tobacco
Vaping, Underage
Human Factors Validation and Usability Testing of the IKE Age-Gating System
A multi-center human factors validation study to demonstrate the function of the IKE Bluetooth system on a chip (SoC) and mobile applications ability to age-gate a device, accurately identify an individuals age, race/ethnicity…
- Trial name
- NCT06952569
- Testing
- IKE System
- Where
- 4 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- IKE Tech
Smoking, Smoking Cessation
Addressing Parental Tobacco Use in Somali Immigrant Families: Adapting an Evidence-Based Intervention in Primary Care
This study will modify an existing evidence-based parental tobacco cessation intervention (the Clinical Effort Against Secondhand Smoke Exposure, or CEASE) delivered in pediatric primary care clinics to address shared tobacco use…
- Trial name
- NCT06839729
- Testing
- CEASE+
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking Cessation
Smoking Cessation After Hospitalization for a Cardiopulmonary Illness
Smoking-related cardiopulmonary diseases account for a large number of hospital admissions. We investigated the efficacy of hypnotherapy as an aid to a counseling-based smoking cessation program in improving quit rates of…
- Trial name
- STOPP (NCT01791803)
- Testing
- hypnotherapy, Nicotine
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- North Shore Medical Center
Electronic Cigarettes
Assessment of Two New Electronic Cigarettes in Cigarette Smokers
The purpose of this study is to determine differences in nicotine delivery, user behavior, subjective effects, and physiological effects, when cigarette smokers use an two new electronic cigarette devices (JUUL and IQOS) relative…
- Trial name
- NCT03435562
- Testing
- JUUL electronic cigarette, IQOS electronic cigarette, Own Brand cigarette
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Smoking Cessation, Health Literacy
Comparison of the Health Literacy of Our Patients Who Quit Smoking and Who Cannot Quit Smoking
The aim of the study was determined to examine the relationship between the health literacy scales of the patients who came to the smoking cessation clinic and their smoking cessation success.
- Trial name
- NCT04896554
- Testing
- Health literacy scale
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Recurrence, Smoking Cessation
Relapse Prevention With Varenicline
This study aims to determine if varenicline (Chantix®), currently used as a smoking cessation aid, will decrease the likelihood of relapse to smoking following a programmed lapse in the laboratory.
- Conditions
- Recurrence, Smoking Cessation, Substance-Related Disorders
- Trial name
- 0815 (NCT00944554)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Smoking Cessation
Pharmacokinetic Study of 4 mg Nicotine Lozenge.
This is a randomized, single center, open label, single dose, four way crossover study in fasted healthy male subjects to compare the pharmacokinetics of nicotine following administration of 3 prototype 4mg nicotine lozenge to an…
- Trial name
- NCT01669122
- Testing
- nicotine
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Head and Neck Cancer, Lung Cancer
Vanguard Study for Head and Neck Cancer or Non-Small Cell Lung Cancer (NSCLC) Patients
The goal of this research study is to look at how long individuals who have been treated for early stage NSCLC or HNSCC live without developing lung cancer.
- Trial name
- NCT00352391
- Testing
- Assessments
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- M.D. Anderson Cancer Center
Tobacco Use, Smoking
Salvation Army Tobacco Quit Line Referral Implementation Trial
The goal of this clinical trial is to understand how the Salvation Army staff can help people who use tobacco learn about and connect with no-cost treatments to help cut down or quit smoking.
- Conditions
- Tobacco Use, Smoking, Smoking Cessation
- Trial name
- NCT06689774
- Testing
- Cognitive-Motivational Feedback, Staff Tobacco Quit Line Referral Implementation Support, Consumer Incentives for Immediate Referral to a Tobacco Quit Line
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Wisconsin, Madison
Smoking Cessation
Study of Injectable Naltrexone and Oral Bupropion Among Cigarette Smokers With Schizophrenia
The purpose of this study is to assess the feasibility and safety of injectable naltrexone (NTX;380 mg) in conjunction with oral bupropion (BUP; 450 mg daily)NTX-BUP administration among individuals with schizophrenia spectrum…
- Trial name
- NCT06374290
- Testing
- Naltrexone (Vivitrol), Bupropion
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- The University of Texas Health Science Center, Houston
Tobacco Dependence
Bioequivalence Between Two New Oral Nicotine Replacement Therapy Products and Nicorette® Microtab
The purpose of this study is to assess the bioequivalence between two new oral nicotine replacement therapy products and Nicorette® microtab.
- Trial name
- NCT01238640
- Testing
- Code STD, Code STE, Nicorette Microtab
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- McNeil AB
Stage III Oropharyngeal Squamous Cell Carcinoma, Stage IVA Oropharyngeal Squamous Cell Carcinoma
Reduced-Dose Intensity-Modulated Radiation Therapy With or Without Cisplatin in Treating Patients With Advanced Oropharyngeal Cancer
This randomized phase II trial studies the side effects and how well modestly reduced-dose intensity-modulated radiation therapy (IMRT) with or without cisplatin works in treating patients with oropharyngeal cancer that has…
- Conditions
- Stage III Oropharyngeal Squamous Cell Carcinoma, Stage IVA Oropharyngeal Squamous Cell Carcinoma, Stage IVB Oropharyngeal Squamous Cell Carcinoma, Stage IVC Oropharyngeal Squamous Cell Carcinoma
- Trial name
- NCT02254278
- Testing
- Cisplatin, IMRT 6 weeks, IMRT 5 weeks
- Where
- 222 sites in United States, Canada and 2 more
- Volunteers
- 316 people
- Sponsor
- NRG Oncology
Smoking, Tobacco
Examining Brain Responses Linked to Emotion in Individuals Who Smoke Cigarettes
The study will use functional magnetic resonance imaging and facial coding methods to study individuals who smoke cigarettes. Smoking expectancy (the extent to which one perceives an opportunity to smoke a cigarette) will be…
- Trial name
- NCT04310735
- Testing
- Verbal smoking expectancy manipulation
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cigarillo Smoking
Cigarillo Public Education Messaging for Black Young Adults
This is a 3-arm randomized controlled trial to examine the effects of cigarillo public education messages among Black young adults who are at-risk for established cigarillo smoking.
- Trial name
- NCT06863168
- Testing
- Cigarillo Health Harm and Nicotine Addiction Messaging, Cigarillo Health Harm and Nicotine Addiction Messaging Contextualized to Outcome Expectancies
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- Drexel University
Nicotine Dependence, Nicotine Withdrawal
Human Laboratory Study of Varenicline and Bupropion for Nicotine Dependence
The objective of this proposal is to elucidate effects of bupropion SR + varenicline on smoking-cessation related processes in early abstinence using a human laboratory model.
- Trial name
- ChanBan (NCT00749658)
- Testing
- Bupropion, Varenicline
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Vaping, Nicotine Absorption
Study to Investigate the Nicotine Pharmacokinetic Profiles and Pharmacodynamic Effects of P4M3 Variants
This is a single-center, open-label, concentration-ranging study to evaluate the nicotine PK profile and PD effects in healthy adult experienced users of closed tank/cartridge e-cigarettes using four different variants of P4M3…
- Trial name
- NCT03379740
- Testing
- E-cigarette, P4M3-1.7%, P4M3-1.7%LA
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Tobacco Use
Baby Albert: Electronic Cigarette Pharmacokinetics (PK) and Abuse Liability
The overall aim of the current research is to understand purchasing and product choice behaviors of tobacco/nicotine users if banning the sale of fully nicotinized cigarettes were to go into effect.
- Trial name
- NCT03637452
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation
Impact of E-cigarette Nicotine Concentration on Compensation
The study will be the first to assess the impact of nicotine concentration on compensatory puffing (total inhaled volume), nicotine delivery, and switch patterns (percent exclusive EC, dual cig-EC, and cig only users) with an…
- Trial name
- NCT05887947
- Testing
- Electronic Cigarette with 5% Nicotine Concentration, Electronic Cigarette with 1.8% Nicotine Concentration
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Smoking Cessation, Smoking Tobacco
Proactive Tobacco Treatment for Veterans
Tobacco use is the leading cause of premature death in the United States and disproportionately affects Veterans and certain racial/ethnic minority groups.
- Trial name
- NCT00608426
- Testing
- Proactive Outreach with choice of telephone or in-person smoking cessation services
- Where
- 5 sites in United States
- Volunteers
- 6,400 people
- Sponsor
- US Department of Veterans Affairs
Nicotine Use Disorder
Real Time fMRI and Quitting Smoking
This study will examine how real-time functional magnetic resonance imaging (rt-fMRI) feedback can be used to modulate brain activation in the context of smoking cues in order to resist craving.
- Trial name
- NCT03302026
- Testing
- Realtime biofeedback using fMRI
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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