Clinical trials: Smoking, Tobacco
Malformations
Varenicline Pregnancy Cohort Study
A prospective population-based cohort study to examine whether varenicline use during pregnancy is associated with an increased risk of major congenital malformations in infants above that associated with smoking during pregnancy.
- Trial name
- NCT01290445
- Testing
- varenicline, cigarette smoke from maternal smoking, Non-Exposure
- Volunteers
- 885,185 people
- Sponsor
- Pfizer
Gingival Recession, Smoking
The Role of Smoking and Gingival Crevicular Fluid Markers on Coronally Advanced Flap Outcomes
Cigarette smoking is a patient-related factor that can affect healing of periodontal tissues and the success rate of root-coverage procedures.
- Trial name
- NCT03539939
- Testing
- Coronally Advanced Flap
- Volunteers
- 15 people
- Sponsor
- Ege University
Smoking Cessation, Oxidative Stress
ESTxENDS Trial-Substudy on Oxidative Stress Induced by Electronic Nicotine Delivery Systems (ENDS) Measured in Urine
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Oxidative stress outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT03612375)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Smoking Cessation
Positive Psychotherapy for Smoking Cessation Enhanced With Text Messaging: A Randomized Controlled Trial
Positive Psychotherapy for Smoking Cessation (PPT-S) addresses an array of risk factors for poor smoking outcomes (low positive affect, depressive symptoms, and cynical cognitions), while also providing skills that may buffer…
- Trial name
- NCT02997657
- Testing
- Positive Psychotherapy, Standard smoking cessation counseling
- Where
- 2 sites in United States
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Brown University
Smoking Cessation, Health Behavior
A Health Recommeder System to Tailor Message Preferences in a Smoking Cessation Programme
Patients attending the smoking cessation programme at the Virgen del Rocío University Hospital under the SoLoMo clinical trial of the SmokeFreeBrain project and provided with the SoLoMo mobile app will be observed for one year.
- Conditions
- Smoking Cessation, Health Behavior, Smoking, Tobacco, Smoking
- Trial name
- NCT03206619
- Testing
- Social, Local and Mobile
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Seville
Healthy Volunteers
Effects of Smoking, Age and Body Size on Pharmacokinetics, Safety and Tolerability on Tasimelteon in Healthy Subjects
The purpose of this research study is to understand whether there is any difference in the amount of tasimelteon in the blood in smokers versus non-smokers.
- Trial name
- NCT01477619
- Testing
- Tasimelteon
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanda Pharmaceuticals
Smoking, Smoking, Cigarette
The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study
Mobile health (mHealth) will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers.
- Conditions
- Smoking, Smoking, Cigarette, Smoking, Tobacco, Betel Chewer's Mucosa
- Trial name
- NCT06535867
- Testing
- mHealth
- Where
- United States
- Volunteers
- 5,122 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Effects of Smoking on Infant
The Stress Responses of Fetuses and Infants Whose Mothers Smoked During Pregnancy
It is generally understood that smoking during pregnancy has deleterious effects on the developing fetus, although research on smoking during pregnancy has been limited in focus, with most studies focused on birth weight of…
- Trial name
- NCT00563966
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Smoking Cessation
A Single Dose Study Investigating the Absorption and Elimination as Well as the Tolerability of Varenicline Transdermal Delivery System (e.g., a Patch) as Compared to Oral Varenicline in Adult Smokers.
1. To evaluate the absorption and elimination of varenicline Formulation A transdermal delivery system [TDS (patch)] compared to varenicline immediate release tablet (CHANTIX®). 2.
- Trial name
- NCT00661765
- Testing
- varenicline tartrate, varenicline free base
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pfizer
Smoking
Nicotine Pharmacokinetic Profile and Safety of the Tobacco Heating System 2.2 (THS 2.2)
The overall goal of the study is to evaluate the pharmacokinetic (PK) profile (rate and the amount of nicotine absorbed) following a single use of the THS 2.2, a candidate Modified Risk Tobacco Product, compared to the PK…
- Trial name
- NCT01959607
- Testing
- THS 2.2, CC, NRT Gum
- Where
- Japan
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking
Testing Methods of Self-persuasion Involving Cigarette Smoking
Smokers who are not actively engaged in quitting will participate in a study using self-generated text and audio text messages containing reasons to quit smoking.
- Trial name
- NCT02069483
- Testing
- Motivational Interviewing, Tailored Feedback
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Duke University
Smoking, Nicotine
Impact of Daridorexant on Sleep, Daytime Alertness, and Smoking
Tobacco use is the leading cause of preventable death in the U.S., with 480,000 deaths per year and 7.7 million deaths globally.
- Conditions
- Smoking, Nicotine, Tobacco, Addiction
- Trial name
- NCT07328594
- Testing
- Daridorexant 50 mg
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Legacy Health System
Smoking Cessation
Not Quite Ready to Quit
In our communications with the public, the investigators will call this the Not Quite Ready to Quit Smoking Study. One new method to increase quit attempts is to have smokers reduce their cigs/day.
- Trial name
- NCT01866722
- Testing
- Usual care, Reduction, 5Rs
- Where
- United States
- Volunteers
- 560 people
- Sponsor
- University of Vermont
Apical Periodontitis
Effect of Smoking on Periapical Healing After NSRCT
Goal of this prospective observational study is determine effect of smoking on periapical healing after NSRCT. Population includes systemically healthy smokers with radiographic evidence of apical periodontitis will be recruited…
- Trial name
- NCT05799937
- Testing
- Non Surgical Root Canal Treatment
- Where
- India
- Volunteers
- 116 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis
Change in Gingival Volume and Quality of Life Due to Initial Periodontal Therapy in Smokers
The aim of this study is to compare the dimensional changes of the gingiva due to initial periodontal therapy in non-smokers and cigarette smokers and to compare the oral health related quality of life of non-smokers and…
- Trial name
- NCT05719519
- Testing
- Initial periodontal therapy and 3D intraoral scanning
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rijeka
Smoking Cessation
Evaluation of Cessation Preferences of Menthol Smoker
The primary aim of this study is to determine menthol smokers' perception, product preference, and pattern of use across six products including, mint-flavored nicotine gum; non-flavored nicotine gum; mentholated nicotine inhaler…
- Trial name
- NCT02020005
- Testing
- Non-flavored 2mg nicotine gum, Non-flavored 4mg nicotine gum, Mint-flavored 2mg nicotine gum
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
Smoking Cessation
ISTAPS: A Stepped Primary Care Smoking Cessation Intervention
Primary care centers can play a very important role in helping people to stop smoking. There is a large body of research on the effectiveness of specific interventions especially addressed to people who want to stop smoking.
- Trial name
- NCT00125905
- Testing
- Advice, Motivational Interviewing, Nicotine Gum and Patch
- Where
- Spain
- Volunteers
- 3,012 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cigarette Smoker, Current Every Day Smoker
rTMS in Promoting Smoking Cessation and Preventing Relapse in Current Smokers
This trial studies best dose and how well repetitive transcranial magnetic stimulation (rTMS) works in promoting smoking cessation and preventing relapse in current smokers.
- Conditions
- Cigarette Smoker, Current Every Day Smoker, Current Smoker
- Trial name
- NCT03865472
- Testing
- Questionnaire Administration, Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
E-cigarette Use
Middle School Cluster Randomized Controlled Trial (RCT) to Evaluate E-Cigarette Prevention Program: CATCH My Breath
This is a two-arm, cluster randomized trial designed to to evaluate the effectiveness of an e-cigarette curriculum [called the CATCH My Breath (CMB) program] in delaying the onset of e-cigarette use in middle schoolers.
- Trial name
- NCT04843501
- Testing
- CATCH My Breath (CMB) program for E-cigarette prevention among adolescents, Texas Education Agency (TEA) required tobacco prevention program
- Where
- United States
- Volunteers
- 2,059 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Tobacco Smoking
Episodic Future Thinking, Loss Aversion and Cigarette Smoking
Controlled laboratory experiment to examine whether Episodic Future Thinking influences loss aversion and cigarette smoking among adult individuals who currently smoke cigarettes daily.
- Trial name
- NCT05110612
- Testing
- Episodic Future Thinking, Control Episodic Thinking
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Vermont
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