Clinical trials: Smoking
Healthy
Meloxicam 15 mg Tablets Under Fasting Conditions
The objective of this study is to compare the rate and extent of absorption of meloxicam from a test formulation Meloxicam 15 mg Tablets versus the reference Mobic® 15 mg Tablets under fasting conditions.
- Trial name
- NCT00840476
- Testing
- Meloxicam 15 mg Tablets, Mobic® 15 mg Tablets
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Smoking Behaviors, Periodontal Health
Effects of E-Cigarette Use on Oxidative Stress and Matrix Degradation
This cross-sectional observational study aims to investigate the effects of e-cigarette use on oxidative and matrix-degrading pathways in periodontally healthy individuals.
- Trial name
- ECIG-FOXO (NCT07338318)
- Testing
- E-Cigarette Use
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Tobacco Use
EMA for Tobacco Control Policy Research
The study aims to (1) evaluate the effectiveness of the recent renewal of tobacco health warnings (HWs) on noticing and anti-smoking responses, and (2) assess the effect of exposure to point-of-sale (POS) tobacco displays and…
- Trial name
- NCT03235713
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking Cessation
Extended (6-Week) Varenicline Preloading: Does it Facilitate Smoking Reduction and Cessation?
SUMMARY Rationale: Worldwide, cigarette smoking carries a high mortality. Since the available cessation programs are not effective for all smokers, new strategies are necessary for tobacco control.
- Trial name
- NCT02634281
- Testing
- Varenicline
- Where
- Israel
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Tobacco Smoking, Smoking Behaviors
Human Perception of Odors and Odor Blockers
The goal of this clinical trial is to determine whether blockers of perception of key odorants in cigarette smoke have any utility in smoking cessation.
- Trial name
- NCT06191419
- Testing
- Odorants
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Tim McClintock
Smoking, Nicotine
Nicotine Pharmacokinetics and Subjective Effects of Nicotine Pouch 1.0 Compared to Velo® Ice Cool and Zyn® Cool Mint Mini Dry in Healthy Smokers
This is a single-center, randomized, controlled, open-label, cross-over study in healthy smoking subjects to investigate the nicotine pharmacokinetic (PK) profiles of 4 variants of Nicotine pouch 1.0 compared to marketed Velo …
- Trial name
- NCT05317195
- Testing
- NP-1, NP-2, NP-3
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Nicotine Dependence
Coping Skills Treatment for Smoking Cessation
The primary purpose of this study is to evaluate the efficacy of a new type of exposure- and acceptance-based smoking cessation treatment vs.
- Trial name
- Project-WIN (NCT01061528)
- Testing
- Transdermal Nicotine
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Dental Erosion
Effect of Smoking on Saliva Composition and the Development of Dental Erosion
The aim of this study is to investigate whether smoking is associated with changes in salivary composition and/or predisposition to erosion.
- Trial name
- NCT04208802
- Testing
- Use of fluoridated toothpaste, Wearing of an intraoral device with bovine tooth samples, Wearing of an intraoral device with resin samples
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Göttingen
Healthy
Safety and Tolerability of AQW051 in Elderly Healthy Volunteers.
The purpose of this study is to assess safety and tolerability of AQW051 administered in single and multiple doses to elderly healthy volunteers.
- Trial name
- NCT00418002
- Testing
- AQW051
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Novartis
Smoking Cessation, Sleep
The ESTxENDS Trial- Substudy on the Effects of Using Electronic Nicotine Delivery Systems (ENDS) on Sleep Quality.
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Sleep quality outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT03603353)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Cigarette Smoking
Health-Kit Enabled Mobile App for Tobacco Cessation
Tobacco use is the leading preventable cause of death in the US, contributing to more than 480,000 premature deaths each year. The Tobacco Treatment Guidelines underscore the need to offer patients who use tobacco products brief…
- Trial name
- NCT06292130
- Testing
- refresh
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Pro-Change Behavior Systems
Lung Cancer, Heart Disease
Communicating Smoking Risks Through Graphic Warning Labels
Smoking is the largest preventable health risk in the U.S. The Family Smoking Prevention and Tobacco Control Act of 2010 mandated the placement of larger pictorial warnings on cigarette packs as well as nine new statements of…
- Trial name
- NCT01782053
- Testing
- Picture warning, Control
- Where
- 2 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tobacco Use Disorder, Smoking
Randomized Trial Assessing the Effectiveness of a Pharmacist-Delivered Program for Smoking Cessation
This randomized trial compared the effectiveness of a three session pharmacist-delivered group program for smoking versus one 5 to 10 minute standard care session delivered over the telephone on 7-day point prevalence quit rates.
- Trial name
- NCT00670904
- Testing
- Pharmacist-delivered group program for smoking cessation, Brief standard care session for smoking cessation delivered over the telephone
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Montana
Smoking Cessation, Cigarette Smoking
Treating Smokers With Mental Illness
This is a smoking cessation study that will enroll smokers who have been diagnosed with a severe mental illness. The study will use a combination of intensive tobacco treatment counseling and nicotine replacement therapy to…
- Conditions
- Smoking Cessation, Cigarette Smoking, Schizophrenia, Psychotic Disorders
- Trial name
- NCT03822416
- Testing
- Nicotine patch, Nicotine lozenge, Therapy
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking Cessation
Smoking Cessation Programme in Workplaces in Hong Kong (Phase Ⅴ)
Smoking causes cardiovascular and respiratory diseases, cancers and diabetes, and it has been a leading risk factor for death globally.
- Trial name
- NCT04772521
- Testing
- General health talk, Personalized chat-based interactions, Text message
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking Cessation
Helping Moms Who Smoke
The purpose of this study is to learn how women's smoking changes during their pregnancy and as a new mom, and to assess the help they receive from their health care providers.
- Trial name
- NCT03104452
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Smoking Cessation
Smoking Cessation Programme in Workplaces in Hong Kong (Phase III)
Smoking causes cardiovascular and respiratory diseases, cancers and diabetes, and it has been a leading risk factor for death globally.
- Trial name
- NCT03142555
- Testing
- Health talk plus intensive social media intervention, Health talk plus less intensive social media intervention
- Where
- Hong Kong
- Volunteers
- 679 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking
Young Adults' Reactions to Low Nicotine Cigarette Advertising
Reducing the nicotine content in combustible cigarettes to non-addictive levels has demonstrated promise as a safe and effective public health strategy for decreasing tobacco-caused morbidity and mortality.
- Trial name
- YLA (NCT04906148)
- Testing
- Advertisement content (explicit vs. implicit), Advertisement content (true vs. misleading)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Prevention, Family Function
Familias Unidas: Preventing Substance Abuse in Hispanic Youth
The focus of this study will be to test the Familias Unidas Intervention program among Hispanic 8th graders in the Miami-Dade County Public School System.
- Conditions
- Prevention, Family Function, Substance Use, Sexual Behavior
- Trial name
- NCT01038206
- Testing
- Familias Unidas
- Where
- United States
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- University of Miami
Infertility
Impact of Male Smoking on the Couple's Infertility
About 15% of couples consult for difficulties achieving pregnancy. In about two-thirds of cases, a male component is identified, but is not always sufficient to explain infertility.
- Trial name
- TABAFERTIMASC (NCT02803658)
- Testing
- smoking behavior, Sperm collection
- Where
- 2 sites in France
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
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