Clinical trials: Smoking, active
Tobacco Use, Cigarette Smoking
Effects of Relighting on Smoke Toxicant Deliveries and Subjective Smoking Measures
Characterize effects of relighting on smoke toxicant deliveries and subjective smoking measures. This will be a within-subject comparison in a single experimental group of 30 smokers who report engaging in relighting behaviors.
- Conditions
- Tobacco Use, Cigarette Smoking, Nicotine Dependence
- Trial name
- NCT06295757
- Testing
- Cigarettes
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Peri-Implant Health, Peri Implant Mucositis
Impact of Smoking on Immune Responses in Peri-implant Health and Disease
Peri-implant diseases are inflammatory conditions affecting the gums and bone around dental implants. Peri-implant mucositis causes inflammation in the gums, while peri-implantitis can also lead to bone loss and, in severe cases…
- Conditions
- Peri-Implant Health, Peri Implant Mucositis, Peri-implantitis
- Trial name
- NCT07750171
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Gazi University
Smoking Reduction, Smoking Behaviors
rTMS-concurrent Behavioral Priming for Reducing Smoking Cravings
The objective of this pilot clinical trial is to test the effects of different types of thinking strategies at the time of repetitive Transcranial Magnetic Stimulation (rTMS), applied to the left Dorsolateral Prefrontal Cortex…
- Trial name
- NCT06228235
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- West Virginia University
Lung Cancer
The Lung PCA: A Multi-Dimensional Atlas of Pulmonary Premalignancy
This protocol pertains specifically to the prospective lung squamous cell carcinoma pre-malignant lesion (PML) cohort that will form a primary study group for the Lung Pre-Cancer Atlas.
- Trial name
- NCT03881098
- Testing
- Bronchoscopies, Sputum Sample, Venipuncture
- Where
- 2 sites in United States
- Volunteers
- 240 people
- Sponsor
- University of Colorado, Denver
Smoking, Smoking Cessation
Actívatexto: Advancing Smoking Cessation and Physical Activity Among Latinos
The purpose of this randomized controlled trial is to assess the efficacy of Actívatexto (Aim 1) and the mediators of the presumed treatment effect (Aim 2) among Latino adults who smoke.
- Conditions
- Smoking, Smoking Cessation, Physical Inactivity
- Trial name
- NCT06926608
- Testing
- Actívatexto, Decídetexto
- Where
- United States
- Volunteers
- 408 people
- Sponsor
- University of Rochester
Smoking Cessation
Libre Del Cigarrillo: Development of an mHealth Smoking Cessation App to Extend Reach of a Validated Smoking Cessation Intervention for Spanish-speaking Smokers
Pilot randomized controlled trial evaluating feasibility, acceptability, and trial-readiness of the new app compared with the existing print booklets and the NCI SmokefreeTXT en Español program.
- Trial name
- NCT07754448
- Testing
- Libre del Cigarrillo Smartphone App, Libre del Cigarrillo Printed Booklets, SmokefreeTXT en Español
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
E Cigarette Use
Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users
This study aims to investigate the acute effects of a circuit breathing intervention on nicotine withdrawal symptoms and respiratory parameters among youth who use e-cigarettes.
- Trial name
- NCT07886099
- Testing
- Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Teachable Moment to Opt-out of Tobacco: Interactive Voice Response Quit Line for Veteran Active Smokers With Lung Nodules
The purpose of this study is to evaluate the effectiveness of a smoking cessation outreach intervention (TeaM OUT) on increasing use of smoking cessation resources in Veterans.
- Conditions
- Solitary Pulmonary Nodule, Multiple Pulmonary Nodules, Tobacco Use
- Trial name
- TeaMOUT (NCT04574518)
- Testing
- TeaM OUT Intervention, Enhanced Usual Care
- Where
- 3 sites in United States
- Volunteers
- 223 people
- Sponsor
- VA Office of Research and Development
Lung Cancer Screening
LDCT-SC-FI Low-dose CT Screening for Lung Cancer
This is a randomized phase II trial investigating different smoking cessation methods in study subjects undergoing lung cancer screening with low-dose CT (LDCT).
- Trial name
- NCT05630950
- Testing
- Smoking cessation mobile application, Written material for smoking cessation
- Where
- 2 sites in Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Diabetes Mellitus, Type 2, Nicotine Dependence, Cigarettes
Effect of Glucagon-like Peptide-1 (GLP-1) Receptor Agonist Stimulation on Smoking Consumption in Type 2 Diabetes Patients
Diabetes has become an increasingly serious global health issue. In 2024, approximately 537 million adults were living with diabetes, and this number is projected to rise to 783 million by 2045, representing a 46% increase.
- Trial name
- NCT06924697
- Testing
- Application of GLP-1RAs drugs, DPP-4i group
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Shanghai East Hospital
E-cigarette Use, Substance Use
The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian Youth
The purpose of this research proposal is to develop and evaluate a culturally grounded, ENDS prevention intervention for rural Hawaiian youth. This will be accomplished through two specific aims.
- Trial name
- NCT06929520
- Testing
- ENDS Prevention Intervention (TBD)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Cystic Fibrosis
Study of the Prevalence of Active/Passive Smoking and Vaping Among Patients With Cystic Fibrosis
In the collective unconscious, a patient with cystic fibrosis does not smoke. This belief is so deeply rooted that there is virtually no French data on the prevalence of smoking among this vulnerable population.
- Trial name
- Taba-Muco (NCT07342920)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Newly Diagnosed Cancer Patients
Smoking Cessation Intervention for Cancer Patients
The purpose of this study is to see if we can find ways to improve the treatment of tobacco dependence in patients who have cancer or may have cancer.
- Trial name
- NCT00575718
- Testing
- Hospital Counseling + Nicotine Replacement Therapy. questionaires, Hospital Counseling + Nicotine Replacement + Presurgical Scheduled Reduced Smoking, questionaires
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Tobacco Cessation, Tobacco Dependence
FRESH Delivers: An Innovative Approach to Reducing Tobacco Use Among Rural Smokers
The long-term goal of FRESH Delivers is to fill a critical gap in knowledge on the role of a home-based food delivery social intervention in the elimination of tobacco-caused cancer health burdens.
- Conditions
- Tobacco Cessation, Tobacco Dependence, Food Security
- Trial name
- NCT05429892
- Testing
- Smoking cessation counseling and food delivery, Smoking cessation counseling, Food delivery
- Where
- United States
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Bladder Cancer
Determinants of Bladder Cancer Recurrence Study (The DETER Study)
The purpose of this study is to learn how different lifestyle factors, such as cigarette smoking and body weight, change after a diagnosis of bladder cancer, and how they influence who gets a bladder cancer recurrence and who…
- Trial name
- NCT02400944
- Testing
- questionnaires, Saliva and/or urine sample
- Where
- 4 sites in United States
- Volunteers
- 600 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Peri-implantitis
Investigation of Macrophage Polarization in Peri-implant Health and Peri-implantitis
Peri-implantitis is a chronic inflammatory disease characterized by plaque-associated inflammation of the peri-implant mucosa and progressive loss of supporting bone around dental implants, which may ultimately lead to implant…
- Trial name
- NCT07569432
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Biruni University
Respiratory Abnormality, Pulmonary
The Study Examined the Acute Effects of Wim Hof on Aerobic Training and Cardiodynamics.
Researchers will split the sixty healthy smokers in half. Thirty people will serve as a control group and will be asked to walk or jog at a controlled pace for twelve minutes as part of an aerobic exercise program.
- Conditions
- Respiratory Abnormality, Pulmonary, Exercise Training
- Trial name
- NCT07399119
- Testing
- aerobic exercise where it included walking/ jogging with a controlled speed by the participant, Wim Hof Breathing Method
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Cairo University
Electronic Cigarette Use
Developing and Testing Health Warning Labels on the ENDS Device
In this project, after systematically developing electronic nicotine delivery systems (ENDS) pictorial health warning labels (HWLs), a proven clinical lab model will be used to examine and test their effect when these are placed…
- Trial name
- NCT04907136
- Testing
- Preferred ENDS, Preferred ENDS with HWL
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Florida International University
Smoking Cessation
Family-Based Financial Incentives Intervention for Smoking Cessation
The current study will conduct an RCT to evaluate the effectiveness of a family-based incentive intervention with Alaska Native/American Indian families.
- Trial name
- Aniqsaaq-RCT (NCT06556433)
- Testing
- Financial Incentive Rewards
- Where
- United States
- Volunteers
- 1,312 people
- Sponsor
- Mayo Clinic
Nicotine Addiction
Developing Evidence to Inform Regulatory Policy on Nicotine Content in E-Liquids
The goal of this observational study is to learn if electronic cigarette users who currently choose to use lower nicotine eliquids have reduced harm compared those who choose higher nicotine eliquids.
- Trial name
- NCT06619964
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Rochester Institute of Technology