Clinical trials: Smoking ( Cigarette)
Smoking Cessation, Harm Reduction
Assisting Smokers to Switch to a JUUL E-Cigarette by Devaluing Combustible Cigarettes
This study will evaluate a reward devaluation strategy in which smokers use the JUUL e-cigarette immediately before any combustible cigarettes (CCs) are smoked.
- Conditions
- Smoking Cessation, Harm Reduction, E-Cig Use, Cigarette Smoking
- Trial name
- RECON (NCT04188197)
- Testing
- JUUL
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Nicotine, E-liquid Flavors
Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes
The goal of this application is to test whether menthol and fruit flavors impact e-cigarette use through dissociable mechanisms and exert their effects differentially across nicotine doses.
- Trial name
- NCT04038515
- Testing
- Nicotine 0 mg/mL, Nicotine 6 mg/mL, Nicotine 12 mg/mL
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking, Cigarette, Electronic Cigarette Use
Dual Use of ENDS and Combustible Cigarettes
This study investigates the degree to which shared behavioral processes underlie combustible cigarette (CC) and electronic nicotine delivery system (ENDS) use in young adult dual users of these products in both the laboratory and…
- Trial name
- DUET (NCT05280535)
- Testing
- Cue Reactivity Task, Computerized Visual Dot Probe, Choice Task
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Brown University
Vascular Health
Investigation of the Effects of Electronic Cigarettes on Vascular Health
The goal is find out if the use of Electronic cigarettes (EC) leads to the same changes that we see in blood vessels of traditional cigarettes (TC) users.
- Trial name
- NCT03041493
- Testing
- Electronic cigarette, traditional cigarette
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Electronic Cigarette Use
Assessing the Effect of Flavor on ENDS Users' Experiences and Exposures
Recently, Maziak established a clinical lab at FIU to test the potential of waterpipe tobacco flavor regulation by the FDA. Given the importance of flavors on adolescent ENDS uptake and use, this lab is equipped to study the…
- Trial name
- NCT04192032
- Testing
- Preferred Juul pod flavor (5% nicotine), Classic Tobacco Juul pod flavor (5% nicotine), Preferred flavor with HWL
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Florida International University
Nicotine Addiction, E-Cig Use
Sex Differences in E-cig Perception: Study 1
The primary objective is to examine the influence of sex on sensory effects, appeal, and reinforcing value of nicotine containing e-cigs in popular flavor components; sweet and cooling.
- Conditions
- Nicotine Addiction, E-Cig Use, Cigarette Smoking, Sex Differences
- Trial name
- NCT05432830
- Testing
- E-liquid Flavor 1, E-liquid Flavor 2, E-liquid Flavor 3
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking
Nicotine Metabolism and Low Nicotine Cigarettes
This study examines the effects of smoking low nicotine cigarettes in different groups of smokers. The investigators are focusing on differences in how smokers' bodies break down and eliminate nicotine from their systems.
- Trial name
- NCT01898507
- Testing
- Low nicotine cigarettes
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cigarette Smoking
Postnatal Smoking Relapse, Its Associated Risk Factors, and a Proactive Sustainable Preventive Intervention
This study will assess the extent of postpartum smoking relapse among Romanian women, the associated risk factors, and will develop, implement, and pilot-test a randomized trial smoking relapse intervention incorporating…
- Trial name
- PRISM (NCT02258568)
- Testing
- Smoking abstinence counseling
- Where
- Romania
- Volunteers
- 397 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Smoking
Neurobiology of Nicotine and Non-nicotine Components of Tobacco Addiction
In the present study the investigators will measure the effects of nicotine and non-nicotine factors on brain function during cognitive processes that are differentially sensitive to these factors.
- Trial name
- NNN (NCT01056926)
- Testing
- Quit smoking, Nicotine patch
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Duke University
Cigarette Smoking
A Randomized Controlled Trial to Test the Effect of a Smartphone Quit Smoking Intervention on Young Adult Smokers
The primary aim of this study will be to determine the effectiveness of a smartphone delivered app for young adult smokers on quitting smoking.
- Trial name
- NCT01983150
- Testing
- Crush the Crave Application, On the Road to Quitting - Self Help
- Where
- Canada
- Volunteers
- 1,601 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Nicotine Addiction, E-Cig Use
Quit Smoking Study for People Who Use E-Cigarettes
The overarching aim of this proposed randomized controlled trial (RCT) is to test nicotine replacement therapy (NRT) with text message support for two smoking cessation approaches among young adult dual users of combustible…
- Conditions
- Nicotine Addiction, E-Cig Use, Quitting Smoking
- Trial name
- NCT04946825
- Testing
- Nicotine replacement therapy patch, Nicotine replacement therapy lozenge, Quit electronic cigarettes
- Where
- United States
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Cigarette Smoking, Nicotine Dependence
Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches
Tobacco-free oral nicotine pouches (such as Zyn brand) are a less harmful alternative to cigarette smoking. Pouches, however, contain nicotine, and addictive substance that is not risk-free.
- Conditions
- Cigarette Smoking, Nicotine Dependence, Smoking Cessation
- Trial name
- Pack2Pouch (NCT06678789)
- Testing
- High Nicotine Dose, Low Nicotine Dose
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina