Clinical trials: Smoking Abstinence
Smoking, Smoking Cessation
BRP1802 Smoking Abstinence Study
A single-center study designed to evaluate changes in short-term biomarkers of potential harm (BoPH) in healthy adult cigarette smokers of two age groups (Group A: 24-34 years; Group B: 35-60 years) during 14 days of smoking…
- Conditions
- Smoking, Smoking Cessation, Tobacco Use
- Trial name
- NCT04979013
- Testing
- Smoking Abstinence
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Tobacco Abstinence
Varenicline For Smokers In Recovery From Alcohol Dependence
The goal of this proposal is to explore the potential effectiveness of varenicline to treat tobacco dependence among recovering alcoholic smokers who, as a group, are at high risk for tobacco-caused morbidity and mortality.
- Trial name
- NCT01092702
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Nicotine Dependence
Brain Activity and Smoking Cessation
In the current study, the investigators propose to test: (1) whether brain activation and connectivity in a resting state, assessed by ASL perfusion MRI, BOLD fMRI, and diffusion tensor imaging (DTI) predicts smoking relapse, and…
- Trial name
- NCT01186055
- Testing
- Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tobacco Addiction
Duration of Behavioral Counseling Treatment Needed to Optimize Smoking Abstinence
The purpose of this study is to determine if extending the behavioral smoking-cessation treatment period to one year will significantly improve cessation outcomes among those planning a quit attempt.
- Trial name
- EDC (NCT01038414)
- Testing
- Extended Duration Behavioral Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Harvard University Faculty of Medicine
Smoking Cessation
The Use of Nicotine Patches Together With E-cigarettes (With and Without Nicotine) for Smoking Cessation
A randomised trial to determine whether e-cigarettes (with and without nicotine) combined with nicotine patches and behavioural support can assist smokers in remaining abstinent for at least six months.
- Trial name
- ASCEND-II (NCT02521662)
- Testing
- Nicotine patch, e-cigarette, Nicotine
- Where
- New Zealand
- Volunteers
- 1,124 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Smoking
Reduced Exposure Study in Smokers Using the Tobacco Heating System 2.2 (THS 2.2) for 5 Days in a Confinement Setting
The overall goal of the study is to evaluate if the ad libitum use of the Tobacco Heating System 2.2 (THS 2.2) for 5 consecutive days by adult Japanese healthy smokers affects the levels of biomarkers of exposure for selected…
- Trial name
- NCT01970982
- Testing
- Tobacco Heating System (THS 2.2), Smoking abstinence (SA), Conventional cigarette (CC)
- Where
- Japan
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking Cessation Intervention, Smoking Abstinence
Boosting Chinese Healthcare Service Providers' Utilization of Smoking Cessation Interventions by 'WeChat WeQuit' Program
In this single-blind, randomized trial, undertaken in China with 8-week interventions and follow-up to 52 weeks, about 2,200 providers will be randomly allocated to the intervention or control group.
- Trial name
- NCT03556774
- Testing
- 'WeChat WeQuit' smoking cessation training program
- Where
- China
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Smoking Cessation
Effect of Stress-management and Biofeedback on Craving in Smoking Abstinence: A Pilot Study
Craving is one of the most prominent reasons for relapse after smoking cessation. Mainly pharmacological aids (NRT, bupropion, varenicline) try to counter this condition.
- Trial name
- NCT01080092
- Testing
- breathing technique, behavioral strategies
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Tobacco Smoking
Smoking Interventions in the General Population
The study takes up two problems: 1) Little research exists about general population interventions for smokers not ready to quit within the foreseeable future.
- Trial name
- NCT00678938
- Testing
- Smoking abstinence oriented expert system intervention, Smoking reduction oriented expert system intervention
- Volunteers
- 1,462 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Smoking, Tobacco
A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers
The overall purpose of this study will be to assess primary combustible cigarette users' abstinence from smoking their usual brand of combustible cigarettes at the end of the study, when provided with an electronic nicotine…
- Trial name
- NCT07598136
- Testing
- P2613422, P2611222, P2615522
- Where
- 7 sites in United States
- Volunteers
- 1,280 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Cigarette Smoking, Tobacco Smoking
Working Inside for Smoking Elimination
The purpose of this study is to determine the extent to which an Intentional Behavioral Intervention will increase tobacco quit rates post release among incarcerated men and women.
- Trial name
- WISE (NCT01122589)
- Testing
- Motivational Interviewing/CBT, CONcise Tapes Reviewing Obstacles to healthy Living (CONTROL)
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Smoking Cessation
12-Month Efficacy of Exercise and Cytisinicline for Tobacco Abstinence
Current scientific evidence demonstrates the relationship between good physical fitness and a lower incidence of certain chronic diseases, including smoking, as well as the effectiveness of cytisinicline.
- Trial name
- MEDSEC-CTA12 (NCT06579846)
- Testing
- Cytisinicline and exercise, Cytisinicline
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Smoking Cessation, Tobacco Use Disorder
A Randomized Trial of Internet Access to Nicotine Patches
People who smoke cigarettes have an increased risk of developing emphysema, heart disease, and certain types of cancer. This study will evaluate the effectiveness of providing free nicotine patches from an online smoking…
- Trial name
- iQS (NCT00534404)
- Testing
- Nicotine patches, Telephone counseling, iQuit Smoking website
- Where
- United States
- Volunteers
- 2,485 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Smoking, Tobacco
A Study to Determine the Effect of Access to Multiple Tobacco Flavor Options on Smoking Abstinence Among Primary Cigarette Smokers Using an Electronic Nicotine Delivery System
This is a multi-site, open-label, single arm study to evaluate the rate of smoking abstinence by the end of the study with healthy adult consumers of cigarettes when provided with an e-cigarette over a 13 week study period.
- Trial name
- NCT07879638
- Testing
- FT25614, FT25615, FT25616
- Where
- 5 sites in United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
HRT, Non-HRT
Tobacco Cessation in Postmenopausal Women
This study investigated whether being on transdermal hormone replacement therapy (HRT) influenced smoking cessation variables in postmenopausal women undergoing short-term abstinence from cigarettes.
- Conditions
- HRT, Non-HRT, Continued Smoking, Smoking Abstinence
- Trial name
- NCT01210586
- Testing
- Part 2
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Inflammation, Oxidative Stress
Reduction of Exposure, Inflammation, and Oxidative Stress Following at Least 2 Years of Switching to THS Use Compared to Cigarette Smoking
This is a cross-sectional 3-group study with subjects enrolled and matched by region (Asia, Europe), age, sex, and average daily product consumption over the last 2 years as self-reported.
- Conditions
- Inflammation, Oxidative Stress, Smoking, Smoking Abstinence
- Trial name
- NCT05385055
- Testing
- THS use, Cigarette smoking, Smoking abstinence
- Where
- 37 sites in Bulgaria, Czechia and 4 more
- Volunteers
- 974 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking, Smoking Cessation
Preventing Relapse Following Involuntary Smoking Abstinence
The prevalence of tobacco use in the military is too high. This study is designed to take advantage of the 8.5 weeks of forced tobacco cessation during Basic Military Training and develop effective interventions to prevent…
- Trial name
- AFV (NCT01374724)
- Testing
- Tobacco Use Ban, Tailored Pamphlet, Informational Pamphlet
- Where
- 2 sites in United States
- Volunteers
- 23,000 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Smoking
Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting and 85 Days in an Ambulatory Setting
The main goal of the study is to evaluate if the ad libitum use of the THS 2.2 Menthol (mTHS 2.2) for 5 days in confinement and after 85 days of product use in an ambulatory setting, by Japanese adult healthy smokers results in a…
- Trial name
- NCT01970995
- Testing
- THS 2.2 Menthol (mTHS 2.2), Smoking Abstinence (SA), Menthol Conventional Cigarette (mCC)
- Where
- Japan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Nicotine Dependence, Smoking
The Effect of Exercise on Acute Nicotine Withdrawal
The primary aim of this project is to test the effect of exercise on acute nicotine withdrawal. Acute nicotine withdrawal is characterized by a complex array of symptoms associated with increased risk of relapse among individuals…
- Conditions
- Nicotine Dependence, Smoking, Sleep Disorders, Intrinsic
- Trial name
- NicEx (NCT01047930)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh