Clinical trials: Smoking Behavior
Tobacco Use, Periodontitis
Snuff Use, Smoking, Periodontal Health and Premature Death: 30-year Study
Snuff use and smoking associated with poor periodontal health, especially if used together.
- Trial name
- NCT03614871
- Testing
- Epidemiological study
- Volunteers
- 1,676 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Tobacco Use Cessation
Feasibility, Adoption and Efficacy of A Virtual Reality Smoking Cessation Program for Patients Undergoing Lung Cancer Screening
Lung cancer is the second most common cancer and the leading cause of cancer related deaths in the United States (US . Tobacco use is the leading cause of lung cancer and tobacco control continues to be the primary method of lung…
- Trial name
- NCT06021652
- Testing
- MindCotine Virtual reality
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Nicotine Dependence
Sensitivity to Intravenous Nicotine: Genetic Moderators
To determine if the mu opioid receptor gene (OPRM1) A118G polymorphism moderates the subjective-rewarding effects of intravenous (IV) nicotine in male and female smokers.
- Trial name
- NCT00969137
- Testing
- saline, Nicotine
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking Cessation
Neuro Biomarkers of Smoking Behavior
The purpose of this study is to evaluate cognition in smokers and nonsmokers. It involves administration of intranasal insulin (Novolin R), an investigational medication followed by a brief non-invasive cognitive test.
- Trial name
- NCT03811951
- Testing
- Novolin R
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Cigarette Smoking Toxicity, Nicotine
The Acute Cardiovascular Effects of Nicotine in E-cigarettes (ACE) Study
The goal of this project is to evaluate the nicotine induced acute cardiovascular changes in E-Cigarette users and also study the mechanism involved particularly with vascular impairment.
- Conditions
- Cigarette Smoking Toxicity, Nicotine, Acute Cardiovascular Disease
- Trial name
- ACE (NCT03010995)
- Testing
- Prazosin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
Smoking, Tobacco
Impact of Positive Mental Vs. Physical Health Messaging on Motivation to Stop Smoking
This study tested whether positive messages on tobacco packaging about the mental health benefits of quitting smoking could help motivate people to stop smoking.
- Trial name
- NCT06762756
- Testing
- Messages on tobacco packaging labels
- Where
- United Kingdom
- Volunteers
- 631 people, healthy volunteers welcome
- Sponsor
- Katherine Sawyer
Smokers, Workplace
Evaluation of a Workplace Smoking Cessation Program in Hong Kong (Phase VI)
This study aims to test, by a 2-arm RCT, the effectiveness of an intervention that includes mobile phone-supported simple physical exercise for smoking cessation in workplaces in Hong Kong.
- Conditions
- Smokers, Workplace, Exercise
- Trial name
- NCT05758272
- Testing
- mobile phone-based simple physical exercise reminder to help quit smoking, regular text-based intervention
- Where
- Hong Kong
- Volunteers
- 646 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking Cessation
Disease Management for Smoking Cessation
The primary aim of this study is to assess the effectiveness of both high and low intensity, disease management programs for smoking.
- Trial name
- NCT00440115
- Testing
- High intensity disease management, Low intensity disease management, Comparison group
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Prevention, Family Function
Familias Unidas: Preventing Substance Abuse in Hispanic Youth
The focus of this study will be to test the Familias Unidas Intervention program among Hispanic 8th graders in the Miami-Dade County Public School System.
- Conditions
- Prevention, Family Function, Substance Use, Sexual Behavior
- Trial name
- NCT01038206
- Testing
- Familias Unidas
- Where
- United States
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- University of Miami
Shisha
Developing and Pilot Testing an Intervention to Reduce Household Shisha Smoke Exposure Within Somali Homes
Previous qualitative research among Somali American adults in Minnesota have identified high levels of hookah or shisha (hereafter shisha) use in Somali households.
- Trial name
- NCT06316947
- Testing
- CHW-delivered intervention
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Use Disorder, Dual Tobacco Use
Addictive Potential of LCCs in Dual Users
This study is about whether or not little cigars and cigarillos cause or maintain addiction, and if flavors, such as fruit, make them more addictive.
- Conditions
- Tobacco Use Disorder, Dual Tobacco Use, Tobacco Dependence, Smoking
- Trial name
- NCT03496077
- Testing
- Flavored and unflavored little cigars/cigarillos (LCCs)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- UConn Health
Smoking, Nicotine
Nicotine Pharmacokinetics and Subjective Effects of Nicotine Pouch 1.0 Compared to Velo® Ice Cool and Zyn® Cool Mint Mini Dry in Healthy Smokers
This is a single-center, randomized, controlled, open-label, cross-over study in healthy smoking subjects to investigate the nicotine pharmacokinetic (PK) profiles of 4 variants of Nicotine pouch 1.0 compared to marketed Velo …
- Trial name
- NCT05317195
- Testing
- NP-1, NP-2, NP-3
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smokers
Effect of Behavioral Training on Physiological Responses to Smoking Cues, Affect and Cortisol
This study is ancillary. Participants will be recruited as part of a separate clinical trial on effects of two intensive behavioral training programs that evaluates feasibility and efficacy of a behavioral treatment that includes…
- Trial name
- physio (NCT01362101)
- Testing
- Mindfulness behavioral intervention (MT),cognitive behavioral intervention (CBT)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- A. Eden Evins
Chronic Obstructive Pulmonary Disease (COPD), Asthma
Combined Bio- and Neuro- Feedback vs. Varenicline Use for Smoking Cessation
This study will develop and experimentally test the efficiency of a neurofeedback training protocol vs. varenicline use for smoking cessation.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma, Smoking
- Trial name
- NCT02991781
- Testing
- Biofeedback and Neurofeedback Training, Varenicline use for smoking cessation, Passive Control
- Where
- 3 sites in Bulgaria, Cyprus and 1 more
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Smoking Cessation
Evaluating the Efficacy of E-Cigarette Use for Smoking Cessation (E3) Trial
Smoking-related diseases contribute to the death of more than 37,000 Canadians annually. Of that number, almost one-third die of cardiovascular-related causes.
- Trial name
- NCT02417467
- Testing
- Nicotine E-Cigarette, Non-Nicotine E-Cigarette, Counseling
- Where
- 16 sites in Canada
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- McGill University
Quitting Smoking
Financial Incentives for Smoking Cessation Treatment Engagement
This study is being done to see if financial incentives increase the rate at which smokers engage in cessation treatment. A total of 540 participants will be enrolled by invitation from 6 primary care clinics of the participating…
- Trial name
- NCT04601870
- Testing
- No Financial Incentive, Financial Incentive (100 dollars), Financial Incentive (50 dollars)
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Smoking, Smoking Behaviors
Abuse Liability of Four Modern Oral Nicotine Products
This is a single-site, open-label, randomized, 6-way crossover study designed to evaluate elements of abuse liability (AL) including subjective effects, physiological measures (pharmacodynamics [PD]), and plasma nicotine uptake…
- Conditions
- Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking
- Trial name
- NCT07685795
- Testing
- Usual Brand (UB) filtered, menthol or non-menthol combustible cigarette, Wintergreen (fleece A), 12 mg nicotine, Wintergreen (fleece A), 9 mg nicotine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Healthy Volunteers, Smoking
A Nicotine Pharmacokinetics and Smoking Behaviour Study Examining Cigarette Ingredients
This study will compare nicotine delivery and smoking behaviour in healthy subjects using several combustible cigarette prototypes containing different ingredients which are commonly used in the European Union.
- Trial name
- NCT03272295
- Testing
- Reference cigarette, Cigarette with carob bean extract, Cigarette with cocoa powder
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- British American Tobacco (Investments) Limited
Tobacco Use
Effectiveness of Pedialink CEASE Module
The study involves the testing of a Pedialink module through parent exit interviews in one intervention practice and one control practice.
- Trial name
- NCT01087177
- Testing
- Exposure to practice that has been trained in Pedialink CEASE
- Where
- United States
- Volunteers
- 647 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Smoking Cessation
Smoking Cessation for Hospital Employees With Low Education.
The aim of this trial is to develop a new tailored smoking cessation program for smokers with low education. Smokers are involved in design of the intervention.
- Trial name
- RESPEKT (NCT02701530)
- Testing
- Targeted smoking cessation
- Where
- Denmark
- Volunteers
- 7,003 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen