Clinical trials: Smoking Cessation, completed
Smoking Cessation, Pregnancy
A Smoking Cessation Intervention During Pregnancy in Argentina and Uruguay
Argentina and Uruguay are among the countries with the highest proportion of pregnant women who smoke. The implementation of an effective smoking cessation intervention would have a significant impact on the health of mothers and…
- Trial name
- NCT01852617
- Testing
- Training in smoking cessation counseling
- Where
- 22 sites in Argentina, Uruguay
- Volunteers
- 6,858 people
- Sponsor
- Institute for Clinical Effectiveness and Health Policy
Smoking Cessation, COPD
Effectiveness of Spirometry as a Motivational Tool to Quit Smoking
The aim of the study is to asses the efficacy of the spirometry and a minimal smoking cessation counselling intervention to quit smoking after a year in patients older than 40 years, smokers of more than 10 packs-year and without…
- Trial name
- ESPIMOAT (NCT01821885)
- Testing
- Spirometry and a brief advice to quit smoking, Brief advice to quit smoking
- Where
- Spain
- Volunteers
- 335 people
- Sponsor
- Basque Health Service
Smoking Cessation
Pharmacokinetic Study of 4 mg Nicotine Lozenge.
This is a randomized, single center, open label, single dose, four way crossover study in fasted healthy male subjects to compare the pharmacokinetics of nicotine following administration of 3 prototype 4mg nicotine lozenge to an…
- Trial name
- NCT01669122
- Testing
- nicotine
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Endothelial Dysfunction
Impact of Smoking Cessation and γ-Tocopherol to Restore Vascular Endothelial Function
Cigarette smoking is a significant risk factor for cardiovascular disease (CVD) and is the leading cause of premature mortality in the US.
- Trial name
- NCT01314443
- Testing
- Nicotine Replacement Therapy (NRT), Gamma-Tocopherol, Smoking cessation
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Smoking Cessation
Supplemental Nicotine Administration for Smoking Cessation in Posttraumatic Stress Disorder (PTSD)
The investigators propose to evaluate the relationship between PTSD, mood, craving and withdrawal symptoms and factors associated with relapse in the context of a randomized clinical smoking cessation trial.
- Trial name
- NCT01055886
- Testing
- nicotine patch
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Duke University
Smoking Cessation
Pharmacological Aids for Interactive Smoking Cessation
There is an important need for effective smoking cessation programs that both (a) promote the effective use of pharmacological aids, such as nicotine replacement products and bupropion, and (b) provide cognitive-behavioral…
- Trial name
- NRT_2 (NCT02329249)
- Testing
- Smokefree Partners: 21 Days to Freedom, Wait-List Control
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Oregon Center for Applied Science, Inc.
Smoking Cessation, Nicotine Dependence
Neuropsychological Prognosis Factors of Smoking Cessation
The low overall effectiveness of available smoking cessation treatment so far, indicate the need for new and more efficacious ways to help smokers maintain abstinence. Smokers are a highly heterogeneous population.
- Trial name
- NCT01554436
- Testing
- neuropsychological assessment
- Where
- France
- Volunteers
- 135 people
- Sponsor
- University Hospital, Montpellier
Cancer
Getting Physical on Cigarettes - Smoking Cessation & Relapse Prevention
Adult female smokers will participate in an exercise-aided smoking cessation program, and will then be randomized into one of four cessation maintenance conditions: (a) Exercise Maintenance only (b) Exercise Maintenance + Relapse…
- Trial name
- NCT01305447
- Testing
- Exercise Behaviour Maintenance, Smoking Relapse prevention booklets, Contact control
- Where
- Canada
- Volunteers
- 413 people
- Sponsor
- University of Western Ontario, Canada
Smoking Cessation, Health Behavior
Promoting Smoking Cessation in Carpenters
The purpose of this study is to test an innovative and sustainable intervention to increase participation in a union-sponsored smoking cessation program among carpenters and floor layers.
- Conditions
- Smoking Cessation, Health Behavior, Cancer
- Trial name
- NCT01878214
- Testing
- Targeted messaging, Standard messaging
- Where
- United States
- Volunteers
- 442 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Smoking
Carotid Plaque Screening Trial in Smokers
The purpose of this study is to determine the impact of carotid plaque screening on smoking cessation and control of other cardiovascular risk factors.
- Trial name
- CAROSS (NCT00548665)
- Testing
- Carotid ultrasound for plaque screening, Brief advice for smoking cessation
- Where
- Switzerland
- Volunteers
- 536 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Nicotine Dependence, Smoking
The Effect of Exercise on Acute Nicotine Withdrawal
The primary aim of this project is to test the effect of exercise on acute nicotine withdrawal. Acute nicotine withdrawal is characterized by a complex array of symptoms associated with increased risk of relapse among individuals…
- Conditions
- Nicotine Dependence, Smoking, Sleep Disorders, Intrinsic
- Trial name
- NicEx (NCT01047930)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Smoking Cessation
Efficacy of Tobacco Quitline for Cancer Survivors
The proposed study is a two-armed randomized controlled clinical trial examining the long-term (one-year) efficacy of telephone intervention conditions for smoking cessation in a high risk medical population; namely, cancer…
- Trial name
- NCT00827866
- Testing
- Counselor-Initiated Tobacco Quit Line, Self-Paced Tobacco Quit Line
- Where
- United States
- Volunteers
- 946 people
- Sponsor
- St. Jude Children's Research Hospital
Smoking
Clinical Study of Smoke-Break Liquid Cigarettes
The purpose of this study is to determine whether the Smoke-Break nicotine delivery device can help smokers quit smoking, while avoiding many of the side effects associated with other smoking cessation products.
- Trial name
- NCT00715871
- Testing
- Nicotine, Smoke-Break nicotine delivery device
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Smoke-Break, Inc.
Smoking, Tobacco Use Cessation
Tobacco Tactics Website for Operating Engineers
This is a clustered randomized control trial to test the Tobacco Tactics intervention among Operating Engineers (heavy equipment workers).
- Trial name
- BCBSM-OE (NCT01124110)
- Testing
- Tobacco Tactics Web-Based Intervention, 1-800-QUIT-NOW Telephone Hotline
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Smoking Cessation
Dissemination of Tobacco Tactics for Hospitalized Smokers
Nurse-administered smoking cessation interventions have been shown to be efficacious, but are seldom implemented due to lack of training and time.
- Trial name
- NCT01309217
- Testing
- Tobacco Tactics Intervention, Usual Care
- Where
- 6 sites in United States
- Volunteers
- 1,528 people
- Sponsor
- University of Michigan
Tobacco Use Cessation
Emergency Department Smoking Cessation Study
Tobacco smoke claims approximately 6000 lives annually in BC. In this study, the investigators will determine whether referring smoking patients from the Vancouver General Hospital Emergency Department to the investigators…
- Trial name
- NCT01454375
- Testing
- Referral to QuitNow Services
- Where
- Canada
- Volunteers
- 1,301 people
- Sponsor
- University of British Columbia
Smoking Cessation
Varenicline and Nicotine Interactions in Humans (VA)
To examine the effects of varenicline on the subjective, physiological and cognitive responses to intravenous nicotine. Varenicline is a partial nicotine agonist and it is approved as a treatment for smoking cessation.
- Trial name
- NCT00606892
- Testing
- Varenicline, IV Nic
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking Cessation
Memory Reconsolidation Blockade as a Novel Intervention for Nicotine Dependence
Smoking is the leading cause of preventable morbidity and mortality in the US. While approximately 70% of smokers attempt to quit each year, only 5-15% maintain abstinence for 12 months, even with effective pharmacological and…
- Trial name
- SCP (NCT00916721)
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Smoking Cessation, Schizophrenia
Trial of Nicotine Nasal Spray as an Aid for Smoking Cessation in Schizophrenia
This R01 grant describes a randomized, double-blind, placebo-controlled trial of nicotine nasal spray (NNS) as an aid for smoking cessation in 60 individuals with schizophrenia.
- Trial name
- NCT01010477
- Testing
- Nicotine Nasal Spray, Behavioral counseling
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Rutgers, The State University of New Jersey
Smoking Cessation
Proof-Of-Concept Investigation With a Neurosteroid Analog (Ganaxolone) as a Smoking Cessation Candidate
The purpose of this research study is to evaluate whether the investigational drug ganaxolone can help smokers quit smoking. Ganaxolone is a drug that has been investigated (in other research studies) for the treatment of…
- Trial name
- Ganaxolone (NCT01857531)
- Testing
- Ganaxolone, Nicotine Patch
- Where
- 4 sites in United States
- Volunteers
- 36 people
- Sponsor
- Jed E. Rose