Clinical trials: Smoking Cessation, completed
Smoking Cessation, Electronic Cigarette Use
CAN-DOSE Study: Cessation With Augmented Nicotine for Dual Use Of Smoking and E-cigarettes
Many people smoke cigarettes and use e-cigarettes, and have a hard time stopping. Nicotine replacement therapy medications, such as nicotine patches and lozenges, have been shown to help people quit e-cigarette use.
- Conditions
- Smoking Cessation, Electronic Cigarette Use, Cigarette Smoking
- Trial name
- CAN-DOSE (NCT06087328)
- Testing
- Regular Nicotine patch and lozenge dose, Augmented Nicotine patch and lozenge dose
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Medical University of South Carolina
Smoking Cessation, Vaping Cessation
Safety Study of Cytisinicline in Adult Combustible and/or E-cigarette Smokers
Safety assessment of long-term 3 mg cytisinicline three times daily (TID) exposure for 52 weeks is the main purpose of this study, conducted in the United States.
- Trial name
- ORCA-OL (NCT06435221)
- Testing
- Cytisinicline
- Where
- 29 sites in United States
- Volunteers
- 479 people
- Sponsor
- Achieve Life Sciences
Smoking Cessation
Mobile Chat Messaging for Smoking Relapse Prevention
Most smokers return to smoking (relapse) after making a quit attempt, but evidence of effective intervention to prevent relapse is scarce.
- Trial name
- NCT05370352
- Testing
- Standard smoking cessation treatment, Personalised chat messaging, SMS text messaging
- Where
- 2 sites in Hong Kong
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Tobacco Use, Smoking Cessation
Chatbot Counselling for Smoking Cessation in Youths
The goal of this pilot trial is to develop and examine the trial feasibility and acceptability of a chatbot for smoking cessation in youth smokers. Specific aims include: 1.
- Trial name
- NCT06470776
- Testing
- Chatbot counselling, Peer counselling
- Where
- Hong Kong
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking Cessation, Cancer
Tobacco Treatment Comparison for Cancer Care
This pilot comparative effectiveness trial will compare two active smoking cessation treatments in terms of effectiveness, equity across patient subpopulations, and efficiency among adult patients diagnosed with cancer within the…
- Trial name
- NCT06218823
- Testing
- Transdermal Nicotine Patch, Standard Telephone Counseling, Varenicline
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Wisconsin, Madison
Tobacco Smoking
Financial Incentives for Homeless Smokers: A Community-based RCT
This community-based randomized controlled trial will test the effect of contingent financial rewards on smoking abstinence among homeless-experienced adult cigarette smokers.
- Trial name
- NCT04445662
- Testing
- Financial incentives, Varenicline, Tobacco coaching
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Massachusetts General Hospital
Smoking Cessation
Testing a Novel Smartphone Application for Smoking Cessation With the Oklahoma Helpline
Over 470,000 tobacco users have been served by the Oklahoma Tobacco Helpline (OTH). The OTH reaches a substantial number of smokers each year, but follow-up rates are notoriously low and many smokers may prefer smartphone-based…
- Trial name
- OKquit (NCT05539209)
- Testing
- OKquit, Standard Helpline Care
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation
Evaluation of Cessation Preferences of Menthol Smoker
The primary aim of this study is to determine menthol smokers' perception, product preference, and pattern of use across six products including, mint-flavored nicotine gum; non-flavored nicotine gum; mentholated nicotine inhaler…
- Trial name
- NCT02020005
- Testing
- Non-flavored 2mg nicotine gum, Non-flavored 4mg nicotine gum, Mint-flavored 2mg nicotine gum
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
Smoking Cessation
Study of a Smartphone-Based Switch Program
Prospective, open label, single center clinical study enrolling up to 120 participants to evaluate the Pivot cigarette smoking cessation program in adult smokers, previously unable to quit, who also use other smoke-free nicotine…
- Trial name
- NCT06544772
- Testing
- Pivot cigarette smoking cessation program
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Pivot Health Technologies Inc.
Smoking Cessation
Suvorexant to Reduce Symptoms of Nicotine Use
The purpose of this study is to assess the impact of suvorexant on established measures of smoking relapse risk (craving,withdrawal, stress reactivity, latency to self-administration) and to validate the somnolent effect of…
- Trial name
- NCT04234997
- Testing
- Suvorexant 20 mg, Suvorexant 0mg
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The University of Texas Health Science Center, Houston
Smoking, Low Physical Activity Level
Perfect Fit: Evaluation of a Virtual Coach for Smoking Cessation and Physical Activity
The leading cause of disease burden across the globe is cardiovascular disease (CVD). Important modifiable behavioral CVD risk factors include, amongst others, smoking and low physical activity (PA).
- Trial name
- NCT06095999
- Testing
- Perfect Fit intervention: virtual coaching intervention to quit smoking and increase physical activity
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
ACS, Clonal Hematopoiesis of Indeterminate Potential
CHIP and Residual Cardiovascular Event Tendency After Smoking Cessation
In order to identify the association between clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular risks after smoking cessation, this study intends to recruit ACS patients undergoing complete…
- Conditions
- ACS, Clonal Hematopoiesis of Indeterminate Potential, Smoking Cessation
- Trial name
- CHIP-RETENTION (NCT04987268)
- Testing
- clonal hematopoiesis of indeterminate potential
- Where
- China
- Volunteers
- 1,029 people
- Sponsor
- Shenyang Northern Hospital
Smoking Cessation
Impact of E-cigarette Nicotine Concentration on Compensation
The study will be the first to assess the impact of nicotine concentration on compensatory puffing (total inhaled volume), nicotine delivery, and switch patterns (percent exclusive EC, dual cig-EC, and cig only users) with an…
- Trial name
- NCT05887947
- Testing
- Electronic Cigarette with 5% Nicotine Concentration, Electronic Cigarette with 1.8% Nicotine Concentration
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Smoking Cessation
CoQuit Study for Smoking Cessation
This study investigated the feasibility of a cognitive dissonance-based mobile app for smoking cessation (CDI). Cognitive dissonance refers to the conflict between beliefs and behaviors; interventions are designed to promote this…
- Trial name
- NCT04893460
- Testing
- CoQuit App
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Pulmonary Disease, Chronic Obstructive, Smoking
Electronic Proactive Outreach for Smokers With COPD
Chronic obstructive pulmonary disease (COPD) is one of the most common respiratory diseases, with 90% of cases directly attributable to smoking. Unfortunately, many patients continue to smoke and have an urgent need to quit.
- Trial name
- NCT04462289
- Testing
- Proactive Outreach
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- VA Office of Research and Development
Smoking Cessation
Smartphone Based Smoking Cessation Intervention
Smoking is becoming increasingly concentrated among individuals with the lowest levels of income, education, and occupational status.
- Trial name
- Smart-TR01 (NCT03740490)
- Testing
- Smart-T + NRT, QuitGuide + NRT
- Where
- United States
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation
SmokefreeSGM, A Text-based Smoking Cessation Feasibility Trial for Sexual and Gender Minority Groups
The purpose of this study is to test the feasibility and acceptability of Smokefree Sexual and Gender Minority (SGM), an SGM-tailored version of the SmokefreeTXT text messaging program
- Trial name
- NCT05645354
- Testing
- SmokefreeSGM, SmokefreeTXT
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Lung Cancer - Non Small Cell Squamous
Comparison of Longer-term (5 Year+) Outcomes (Survival) of Smokers, Ex-smokers, Never Smoker and Quitters
Between 2010-2020, the LungCAst observational study followed 3700 patients newly diagnosed with lung cancer across 33 hospitals in Wales and England for 2 years to see if smoking status at time of diagnosis predicted survival…
- Trial name
- LungCast2 (NCT07127263)
- Where
- United Kingdom
- Volunteers
- 525 people
- Sponsor
- Hywel Dda Health Board
Smoking Cessation, Surgical Complications
Perioperative Smoking Cessation BUndle in a Tertiary Care Hospital - Can Turning Virtual Improve Outcomes?
Smoking continues to be a burden to the healthcare system in Canada. It is well-known that smokers suffer more complications and higher risk of mortality after surgery than non-smokers.
- Trial name
- BuTT-Out (NCT04487548)
- Testing
- Remote smoking cessation bundle
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Fraser Health
Smoking Cessation
Quit Smoking Text Message Study
This project will address research gaps and advance the science of smoking cessation by conducting a randomized controlled trial of an evidence-based, population-level quit smoking text messaging program with or without a…
- Trial name
- NCT06111755
- Testing
- SmokefreeTXT, Smartband
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Yale University