Clinical trials: Smoking Cigarette
Nicotine Addiction, E-Cig Use
Sex Differences in E-cig Perception: Study 1
The primary objective is to examine the influence of sex on sensory effects, appeal, and reinforcing value of nicotine containing e-cigs in popular flavor components; sweet and cooling.
- Conditions
- Nicotine Addiction, E-Cig Use, Cigarette Smoking, Sex Differences
- Trial name
- NCT05432830
- Testing
- E-liquid Flavor 1, E-liquid Flavor 2, E-liquid Flavor 3
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yale University
Cigarette Smoking, Nicotine Dependence
Tailored Smoking Cessation Treatment for LIVE FOR LIFE® Participants
The purpose of this study is to ascertain: 1) the rate of smoking cessation obtained using an adaptive treatment algorithm developed in previous clinical trials, in order to calculate cost-effectiveness of the treatment; 2) the…
- Trial name
- LiveForLife2 (NCT01560507)
- Testing
- varenicline (Chantix), bupropion (Zyban), nicotine patches
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Duke University
Tobacco Dependence
Reduced Nicotine Cigarettes in Smokers With Mood and Anxiety Disorders
The overall aim of this project is to evaluate the effect of progressive nicotine reduction in cigarettes on smoking behavior, toxin exposure and psychiatric symptoms in smokers with comorbid mood and/or anxiety disorders.
- Trial name
- NCT01928758
- Testing
- Reduced Nicotine Content Cigarettes, Usual Nicotine Content Cigarettes
- Where
- 2 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Cigarette Smoking, Schizophrenia
Comparison of Varenicline and Placebo for Smoking Cessation in Schizophrenia
The purpose of this proposed pilot study is to examine the use of varenicline in people with schizophrenia to specifically assess tolerability and efficacy for smoking cessation.
- Trial name
- NCT00554840
- Testing
- varenicline
- Volunteers
- 16 people
- Sponsor
- University of Maryland, Baltimore
Smoking, Tobacco Use
Clinical Outcomes of a Nationwide, Naturalistic E-Cig Trial (CONNECT)
The purpose of this study is to measure changes in smoking behavior during and following sampling of an e-cigarette product. E-cigarettes are classified by the US Food and Drug Administration (FDA) as a tobacco product, though…
- Trial name
- CONNECT (NCT03453385)
- Testing
- Electronic Cigarette
- Where
- United States
- Volunteers
- 638 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tobacco Dependence
European Regulatory Science on Tobacco: Policy Implementation to Reduce Lung Diseases (EUREST-PLUS)
The main objective of EUREST-PLUS is to monitor and evaluate the impact of the Tobacco Products Directive (TPD) within the context of FCTC ratification at an EU level.
- Trial name
- EUREST-PLUS (NCT02773836)
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 6,036 people, healthy volunteers welcome
- Sponsor
- European Network For Smoking and Tobacco Prevention
Cigarette Smoking Toxicity
Smoking Topography and Harm Exposure in Menthol Cigarettes
This study will examine how menthol affects smoking when menthol smokers switch to non-menthol cigarettes. Participants will smoke their preferred brand (control) or Camel Crush cigarettes, which have the ability to be menthol or…
- Trial name
- MQAT (NCT01329263)
- Testing
- Menthol to non-menthol
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking, Tobacco Use
Impact of E-cigarette Characteristics on Reinforcement and Tobacco Use Patterns
The purpose of this project is to understand how different e-cigarettes influence their likeability and use among current smokers who try using e-cigarettes.
- Trial name
- NCT03844672
- Testing
- Low Power, High Power, Low Concentration
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Medical University of South Carolina
Nicotine Addiction
Acute and Chronic Nicotine Modulation of Reinforcement Learning
The purpose of this study is to use functional magnetic resonance imaging (fMRI) to investigate the acute and chronic effects of nicotine on motivational behavior and prediction error-related neural activation.
- Trial name
- NicLearning (NCT01830842)
- Testing
- Nicotine polacrilex, satiety, abstinence
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Duke University
Smoking, Cigarette, Smoking, Tobacco
Examination of Low Wattage and High Wattage E-Cigarettes
The overall aim of the proposed study is to evaluate the effect of switching from conventional cigarettes to either a LWe or HWe on smoking behavior, product use patterns and continued use, as well as biomarkers of toxicant…
- Conditions
- Smoking, Cigarette, Smoking, Tobacco, Nicotine Dependence, Exposure to Toxic Agent
- Trial name
- SWITCH (NCT03113136)
- Testing
- Low wattage E cigarette device, High wattage E cigarette device, Usual brand cigarette
- Where
- United States
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Vaping
Responses to E-cigarette Message Source and Presentation
The goal of this clinical trial is to use crowdsourcing to test the effects of a message source (expert and peer) and message presentation types (one-sided and two-sided) to identify the optimal message type for young adults who…
- Trial name
- NCT06274723
- Testing
- Expert, one-sided, Expert, two-sided, Peer, one-sided
- Where
- United States
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Cigarette Smoking, Obesity
Pre to Postoperative Smoking Cessation
The study will evaluate the feasibility of integrating an intensive pre- post-surgical smoking cessation intervention into a hospital setting, and assess measures of postsurgical recovery as a function of smoking cessation status.
- Trial name
- NCT02683161
- Testing
- Varenicline, Contingency Management, Behavioral Counseling
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University