Clinical trials: Social Behavior
Ischemic Heart Disease, Hopelessness
Reducing Hopelessness Through Improved Physical Activity in Adults With Heart Disease: With COVID-19 Considerations
After a 30-year decline, heart disease is projected to increase up to 18% by 2030. Participation rates in cardiac rehabilitation remain extremely low and hopeless individuals are less likely to participate.
- Conditions
- Ischemic Heart Disease, Hopelessness, Physical Activity, Motivation
- Trial name
- Heart Up! (NCT03907891)
- Testing
- Motivational social support from nurse, Motivational social support from nurse with additional support from significant other, Attention control
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- University of Illinois at Chicago
Hypertension
COmmuNity-engaged SimULation Training for Blood Pressure Control
The goal of CONSULT-BP is to train early-stage healthcare providers, including residents and nurse practitioner (NP) students, to mitigate providers' bias, improve communication skills, and enhance providers' ability to develop…
- Trial name
- CONSULT-BP (NCT03375918)
- Testing
- CONSULT-BP Educational Intervention
- Where
- 4 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases
Culturally Tailored HPV Psychoeducational Multimedia Intervention
Community members ages 18 - 45 years old from the El Paso, Texas, U.S.-Mexico Border Region will be recruited to compare psychoeducational multimedia interventions focused on the human papillomavirus (HPV).
- Conditions
- Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases, Intention, Adherence, Patient
- Trial name
- NCT06098690
- Testing
- Culturally Tailored Multimedia Psychoeducational HPV Intervention, General HPV Multimedia Psychoeducational Control Group
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Agitation, Alzheimer's Disease
Efficacy, Safety and Tolerability Study of AVP-923 (Dextromethorphan/Quinidine) for Treatment of Symptoms of Agitation in Participants With Alzheimer's Disease
The objectives of the study are to evaluate the safety, tolerability and efficacy of AVP-923 compared to placebo, for the treatment of symptoms of agitation in participants with Alzheimer's Disease (AD).
- Trial name
- NCT01584440
- Testing
- AVP-923-20, AVP-923-30
- Where
- 44 sites in United States
- Volunteers
- 220 people
- Sponsor
- Avanir Pharmaceuticals
Tobacco Use, Tobacco Smoking
Connecting Alaska Native People to Quit Smoking
The prevalence of smoking among US adults is highest among American Indians and Alaska Native (AI/AN) persons; however, there are a lack of tobacco cessation interventions developed specific to this disparity group.
- Conditions
- Tobacco Use, Tobacco Smoking, Tobacco Use Cessation, Smoking Cessation
- Trial name
- CAN Quit (NCT03645941)
- Testing
- Facebook Group
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Traumatic Brain Injury
Carbamazepine for the Treatment of Chronic Post-Traumatic Brain Injury Irritability and Aggression
The purpose of this study is to determine if carbamazepine reduces irritability and aggression among individuals with traumatic brain injury
- Trial name
- NCT00621751
- Testing
- Carbamazepine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Wake Forest University Health Sciences
Sedentary Lifestyle
Exergame Study for Family Caregivers
The goal of this study is to examine Go\&Grow as a social exergame intervention to increase physical activity and social support, to promote well-being in family caregivers, and to test social support and physical activity as…
- Trial name
- NCT05032872
- Testing
- Social Exergame Treatment Group, Control Group
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Brandeis University
Multiple Osteochondroma, Ollier Disease
Ready to Sail: Evaluating Sailing's Feasibility as Ergotherapy
Background Individuals with rare skeletal disorders frequently experience psychological distress, social isolation, unmet needs, and significant challenges due to limited treatment options.
- Conditions
- Multiple Osteochondroma, Ollier Disease, Osteogenesis Imperfecta
- Trial name
- PaS (NCT06397443)
- Testing
- 5-day sailing activity
- Where
- Italy
- Volunteers
- 8 people
- Sponsor
- Istituto Ortopedico Rizzoli
Vitiligo, Depressive Episode
Mental Health Associations With Vitiligo
This cohort study is a large population-based study in the UK to determine the risks of comorbid mental health conditions (including depression, anxiety and other potential psychological complications of vitiligo) in adults with…
- Conditions
- Vitiligo, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04953338
- Testing
- Exposure of mental health condtion of interest
- Where
- United Kingdom
- Volunteers
- 36,104 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Reproductive Techniques, Assisted
Study to Evaluate if the Addition of r-hLH (Luveris®) to FSH From Day 8 of Ovarian Stimulation is Able to Decrease Total FSH Dose and to Improve Cycle Outcome in Infertile Women Undergoing ART, Who Required High FSH Dose in a Previous Cycle
The present study was designed to investigate, in hyporesponder subjects, that required in a previous assisted reproductive technologies (ART) cycle follicle stimulating hormone (FSH) >3500 International Unit (IU), the…
- Trial name
- Luveris in ART (NCT01071200)
- Testing
- Recombinant human Follicle Stimulating Hormone (r-hFSH) and Recombinant human Luteinizing Hormone (r-hLH), r-hFSH
- Where
- Italy
- Volunteers
- 133 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Underage Drinking
Parental Research on Interventions for Social Media
The prevalence of underage alcohol use continues to be a public health concern. Numerous studies have reported associations between teen drinking tendencies and parental attitudes and beliefs, parental awareness of teen drinking…
- Trial name
- PRISM (NCT04333966)
- Testing
- Interactive Social Networking Site Parent Based Intervention, Active Control
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center
Acute Stroke
Michigan Stroke Transitions Trial
The Michigan Stroke Transitions Trial (MISTT) is a patient-centered randomized control trial that aims to improve the experience of stroke patients after they return home.
- Trial name
- MISTT (NCT02653170)
- Testing
- SCM, SCM and VSSP
- Where
- 3 sites in United States
- Volunteers
- 320 people
- Sponsor
- Michigan State University
Autism Spectrum Disorder
Enhancing Social Competence in Adults With Autism
SENSE Theatre®, combines several well-documented, effective behavioral strategies, such as the inclusion of trained peer models, theatre play techniques involving predictable (i.e., scripted) and flexible (improvised) role-play…
- Trial name
- NCT04349644
- Testing
- SENSE Theatre
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Vanderbilt University Medical Center
COVID-19
Examining How a Facilitated Self-Sampling Intervention and Testing Navigation Intervention Influences COVID-19 Testing
Antigen self-testing kits are more available at this stage in the pandemic, but among vulnerable populations, use is still low and instructions for antigen testing are not typically designed for low health literacy populations.
- Trial name
- NCT05606016
- Testing
- Facilitated Self-Sampling Intervention (FSSI), Testing Navigation Intervention (TNI)., Control
- Where
- 3 sites in United States
- Volunteers
- 1,232 people
- Sponsor
- The University of Texas Health Science Center, Houston
Depression
Dynamics of Inflammation and Its Blockade on Motivational Circuitry in Depression
The main purpose of this study is to examine the effects of infliximab on measures related to depression symptoms. Infliximab is also known by its brand name Remicade.
- Trial name
- NCT03006393
- Testing
- Infliximab
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Emory University
Alzheimer's Disease
Efficacy and Safety Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease
The primary purpose of this study is to determine whether ELND005 is effective in treating symptoms of agitation and aggression in patients with Alzheimer's disease
- Trial name
- NCT01735630
- Testing
- ELND005
- Where
- 70 sites in United States, Canada and 2 more
- Volunteers
- 350 people
- Sponsor
- OPKO Health, Inc.
Autism
Divalproex Sodium vs. Placebo in Childhood/Adolescent Autism
The study is designed to assess the efficacy of treatment with divalproex sodium (DS) vs. placebo in childhood/adolescent autism fulfilling DSM-IV and Autism Diagnostic Interview (ADI) criteria.
- Trial name
- NCT00211757
- Testing
- Divalproex sodium
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Montefiore Medical Center
Problem Behavior, Aggression
Identifying Precursors to Severe Problem Behavior
The primary objective of this research is to evaluate the escalating sequence of behavior that culminates in severe problem behavior (SPB, such as aggression, self-injury, and disruption).
- Trial name
- NCT04097431
- Testing
- Response Blocking
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Lung Transplant Failure and Rejection
Assessment of Donor Derived Cell Free DNA and Utility in Lung Transplantation
The use of Allosure to identify and quantify circulating donor-derived cell-free DNA to quantitate allograft injury in the early post-transplant period and determine its relationship to allograft failure.
- Trial name
- NCT04318587
- Testing
- Allosure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Pablo Sanchez
Hiv, HIV Infections
Standardized Patients to Measure and Address Intersectional Stigma
This study aims to develop and evaluate an intervention to reduce enacted stigma in healthcare settings aimed at people living with HIV (PLWH) and men who have sex with men (MSM) in China.
- Conditions
- Hiv, HIV Infections, AIDS
- Trial name
- NCT04896216
- Testing
- Stigma Reduction Intervention
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Minnesota