Clinical trials: Social Engagement
Cardiorespratory Fitness, Mental Health
The Use of Competition in a School-based Intervention for Increasing Cardiorespiratory Fitness in Adolescents
Regular physical activity offers numerous physical, psychological, and cognitive health benefits. However, physical inactivity among adolescents remains a global concern, with 81% of 11- to 17-year-olds failing to meet WHO's…
- Conditions
- Cardiorespratory Fitness, Mental Health, School-based Intervention
- Trial name
- B2L-M (NCT06699862)
- Testing
- High Intensity Interval Training, High Intensity Interval Training with Competition
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Behavior, Health
Peer-Delivered Episodic Future Thinking for Returning Citizens
The goal of this study is to examine the effectiveness of a brief, episodic future thinking (EFT) intervention in a substance use treatment setting serving returning citizens with substance use disorders (SUD).
- Trial name
- NCT06119503
- Testing
- Elongating Time HOrizons for Reentry (ETHoR), Standardized Episodic Thinking (SET)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Alcoholism, Substance-related Disorders
Treatment Engagement With Technology-assisted Treatment
This research is being done to study whether using an Internet-based program, called the Therapeutic Education System (TES), would be helpful for the treatment of substance use and other psychiatric problems.
- Conditions
- Alcoholism, Substance-related Disorders, Mentally Ill Chemical Abuse, Educational Technology
- Trial name
- TETAT (NCT02674477)
- Testing
- Therapeutic Education System (TES), Treatment as Usual (TAU)
- Volunteers
- 95 people
- Sponsor
- Johns Hopkins University
HIV Infections
Substance Checking Outreach and Pre-Exposure Prophylaxis (PrEP) Engagement Study
Through the proposed Substance Checking Outreach and Pre-Exposure Prophylaxis (PrEP) Engagement (SCOPE) study, the investigators will design and evaluate an overdose prevention and HIV prevention study among people who use drugs…
- Trial name
- SCOPE (NCT05977881)
- Testing
- CHECKIT!
- Where
- United States
- Volunteers
- 493 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Telemedicine
Practical Telemedicine to Improve Control and Engagement for Veterans With Clinic-Refractory Diabetes Mellitus
Diabetes generates significant morbidity, mortality, and costs within the Veterans Health Administration (VHA). Veterans with persistently poor diabetes control despite clinic-based care are among the highest-risk diabetes…
- Trial name
- PRACTICE-DM (NCT03520413)
- Testing
- PRACTICE-DM, Standard VA Home Telehealth
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- VA Office of Research and Development
Emergency Room Utilization
Oscar Health Patient Pings
Oscar spends a significant amount of money every year on high cost high need individuals. With this increase in health care spending, Oscar Health is looking to expand care post emergency room and inpatient utilization for their…
- Trial name
- NCT02923024
- Testing
- Patient Ping
- Sponsor
- University of Pennsylvania
Depression, Anxiety
Evaluation of Text Message Engagement Support of Mindfulness Smartphone Applications
The aim of this study is to assess the usability of two mindfulness smartphone applications (apps) and to evaluate whether text message support can promote engagement with those apps through a 4-week trial comparing support vs.
- Trial name
- NCT03633682
- Testing
- Headspace - Meditation and Mindfulness App, Stop, Breathe, & Think - Meditation and Mindfulness App
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwestern University
Human Immunodeficiency Virus
Cooperative Re-Engagement Controlled Trial (CoRECT)
CoRECT will help identify the important components of a data-sharing partnership between health departments and HIV care providers, and determine the extent to which a health department intervention can increase the number of…
- Trial name
- CoRECT (NCT02693145)
- Testing
- Anti-Retroviral Treatment and Access to Services (ARTAS)
- Where
- 3 sites in United States
- Volunteers
- 1,893 people
- Sponsor
- Centers for Disease Control and Prevention
Healthy Volunteers
Study of ITI-214 in Healthy Volunteers to Determine CNS Engagement
This is a single site, randomized, double-blind, placebo-controlled, within-subjects study design in healthy volunteers. Escalating single doses of ITI-214 will be evaluated using functional magnetic resonance imaging (fMRI) to…
- Trial name
- NCT03489772
- Testing
- ITI-214
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Intra-Cellular Therapies, Inc.
Down Syndrome
A Study of ACI-24 in Adults With Down Syndrome
This study is a prospective multicenter, placebo-controlled, double-blind, randomized study to assess the effect of one dose ACI-24 versus placebo over a 74-week treatment period and 26-week safety follow-up period.
- Trial name
- NCT04373616
- Testing
- ACI-24
- Sponsor
- AC Immune SA
Psychosis Nos/Other
A Treatment Engagement Protocol for Psychiatrically Hospitalized Adolescents at Clinical High Risk for Psychosis
The current study explores the development and use of a family engagement intervention for psychiatrically hospitalized adolescents with emerging psychosis symptoms.
- Trial name
- NCT04314635
- Testing
- Brief family engagement intervention for CHR, Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rhode Island Hospital
Cognitive Change
Impact of Challenging Engagement on Cognition in Older Adults
The study will enroll 90 participants in the "Impact of Challenging Engagement" study and assign them to one of three groups: high-demand photography, moderate-demand photography, and active placebo.
- Trial name
- engAGE (NCT03962439)
- Testing
- High-Demand Photography, Moderate-Demand Photography, At-Home Engagement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Atrial Fibrillation, Arrhythmias, Cardiac
Exercise Activity Intervention With Sensor-Based Engagement in Patients With Atrial Fibrillation
Atrial fibrillation (AF) affects 1 in 4 individuals during their lifetime and continues to increase in frequency and impact. Exercise intervention has established benefits to improve AF symptoms and burden in clinical studies.
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Cardiovascular Diseases
- Trial name
- EASE-AF (NCT06938412)
- Testing
- Physical Activity Intervention Using FitBit Wearable Device
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Apathy, Stroke Sequelae
Accelerated rTMS for Post-Stroke Apathy
This pilot study will investigate the safety, feasibility, tolerability, and preliminary efficacy of accelerated high-dose repetitive transcranial magnetic stimulation (rTMS) targeting the medial prefrontal cortex (mPFC) to…
- Conditions
- Apathy, Stroke Sequelae, Stroke (CVA) or TIA, Stroke/Brain Attack
- Trial name
- NCT05878457
- Testing
- MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Medical University of South Carolina
Depression Disorder, Engagement
Improving Patient Engagement in Mental Health Services
Hybrid Type II Implementation Trial
- Trial name
- NCT07618312
- Testing
- Behavioral Activation
- Volunteers
- 100 people
- Sponsor
- Montana State University
HIV/AIDS
Development of a Couple-Based Mobile Health Intervention for Enhancing HIV Care Engagement Outcomes (N'Gage)
HIV/AIDS among Black men is a US public health crisis, emphasizing the urgency for increased research focus and intervention development.
- Trial name
- N'Gage (NCT03100643)
- Testing
- mHealth N'Gage mobile application
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pain, Opioid Use
Healing After Injury to Reduce Opioid Use and Pain Through Preventive Engagement
The goal of this proposed project is to optimize the adaptive psychological intervention and assess the feasibility and acceptability.
- Trial name
- HOPE (NCT07741201)
- Testing
- Computerized brief intervention, Psychological sessions, Opioid taper recommendations
- Volunteers
- 80 people
- Sponsor
- Henry Ford Health System
Depression
An Adaptive Intervention for Depression Among Latinos Living With HIV
This study will use a pilot sequential multiple assignment randomized trial (SMART) design to build an adaptive treatment strategy (ATS) for depression and engagement in HIV among Latinos living with HIV.
- Trial name
- Latino-SMART (NCT03668379)
- Testing
- Augment w/mHealth, Maintenance, Switch to CBT & mHealth
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Intervention Study
Participant Engagement and Retention Trial in a Public Hospital (PERTH): An RCT Protocol
MAASTHI (Maternal Antecedents of Adiposity Studying the Transgenerational role of Hyperglycaemia and Insulin) is a prospective birth cohort with the aim of assessing the effects of glucose levels in pregnancy on the risk of…
- Trial name
- PERTH (NCT03088501)
- Testing
- Interactive voice response system, Mother and baby affairs workshop
- Where
- India
- Volunteers
- 171 people
- Sponsor
- Public Health Foundation of India
HIV
HIV Prevention and Care Engagement in Nepal
This intervention focuses on increasing HIV testing, HIV medication adherence and reducing intersectional stigma. Our Sweekar intervention will implement 5 months of group-based activities to address the social stigma and HIV…
- Trial name
- NCT07528573
- Testing
- Sweekar intervention
- Where
- Nepal
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
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