Clinical trials: Social Psychology
Heart Transplant Rejection, Heart Transplant Infection
TTV Viral Load in Heart Transplant Recipients
This prospective, multicenter, non-interventional trial aims to study the association between TTV viral load and the occurrence of rejection or infection during the first year after transplantation.
- Conditions
- Heart Transplant Rejection, Heart Transplant Infection, Virus
- Trial name
- TTVCoeur (NCT05064462)
- Testing
- Collection of EDTA blood sample (5 to 7 ml)
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kidney Transplant Failure and Rejection
A Follow up Study of Patients Treated With Imlifidase Prior to Kidney Transplantation
The rationale for the current protocol is to collect data from extended follow up in subjects that have received a kidney transplant following imlifidase dosing to provide a better understanding regarding the long-term outcome…
- Trial name
- NCT03611621
- Testing
- Imlifidase
- Where
- 6 sites in United States, France and 1 more
- Volunteers
- 31 people
- Sponsor
- Hansa Biopharma AB
Heart Failure, Respiratory Failure
Donor Simvastatin Treatment in Organ Transplantation
The aim of the study is to investigate the effects of donor simvastatin treatment on ischemia-reperfusion injury after heart transplantation.
- Conditions
- Heart Failure, Respiratory Failure, Liver Failure, Kidney Failure
- Trial name
- SIMVA (NCT01160978)
- Testing
- Simvastatin 80mg, Control Rx
- Where
- Finland
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Eating Behavior, Social Psychology
The Influence of Fictitious Peers in a Social Media Intervention for Downsizing Portions: The Smart Snacking Studies
The 2 interventions aimed to examine whether peer-led nudging on social media may be a way of influencing young adults and adolescents to reduce their self-reported ideal portion sizes of high energy-dense snacks and…
- Trial name
- NCT04064775
- Testing
- Smart snacking intervention
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Nurse-Patient Relations, Psychology, Social
Meaning-Centered Psychotherapy at Home
The purpose of this study is to train nurses from the VNS Health Visiting Nurse Service to deliver Meaning-Centered Psychotherapy for Palliative Care Patients (MCP-PC) to homebound people, and to evaluate how effective MCP-PC is…
- Trial name
- NCT05495737
- Testing
- Meaning-Centered Psychotherapy/MCP-PC Training, Meaning-Centered Psychotherapy/MCP-PC, Treatment As Usual/TAU
- Where
- 2 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Kidney Transplantation
Noninvasive Methods to Monitor Graft Survival in Kidney Transplant Patients
The purpose of this study is to test noninvasive methods to monitor the health and condition of new kidneys in people who have received kidney transplants.
- Trial name
- NCT00308802
- Testing
- Kidney transplantation
- Where
- 9 sites in United States, Canada
- Volunteers
- 280 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Psychology, Social
the Health Crisis at the Healthcare Professionals, Careers and Non-careers, a Month After the Containment Period
The investigator wish to study, at a distance from the lifting of confinement (1 month), whether the psychological impact on professionals in nursing and non-nursing care establishments is associated with their living context…
- Trial name
- NCT04436861
- Sponsor
- Clinique Medipole Garonne
Glycerin Cryopreserved Acellular Corneal Tissue, Deep Anterior Lamellar Keratoplasty
Deep Anterior Lamellar Keratoplasty (DALK) Using Acellular Corneal Tissue Promotes Corneal Allograft Survival in High Risk Patients
The purpose of this study is to study whether deep anterior lamellar keratoplasty (DALK) using acellular tissue will promote corneal graft survival in high risk patients.
- Conditions
- Glycerin Cryopreserved Acellular Corneal Tissue, Deep Anterior Lamellar Keratoplasty, High Risk Keratoplasty
- Trial name
- NCT01021046
- Testing
- DALK using GCCT, DALK using FCT
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Wenzhou Medical University
Kidney Diseases, Graft Rejection
Renal Function Optimization With Mycophenolate Mofetil (MMF) Immunosuppressor Regimes (ALHAMBRA)
The main aim of this study is to compare the renal function (serum creatinine at 6 months) in the later introduction of tacrolimus or rapamycin based in immunosuppressor regimes with daclizumab, mycophenolate mofetil, and…
- Trial name
- NCT00290069
- Testing
- Tacrolimus, Rapamycin
- Where
- 7 sites in Spain
- Volunteers
- 94 people
- Sponsor
- Sociedad Andaluza de Trasplantes de Organos y Tejidos
Acute Graft Rejection, Chronic Allograft Nephropathy
Study Cyclosporine (CsA) Versus Tacrolimus (Tacro) After Campath Induction in Kidney Transplantation
After alemtuzumab induction, followed with kidney transplantation, patients will be randomly assigned to receive either tacrolimus or cyclosporine microemulsion in combination with mycophenolates.
- Conditions
- Acute Graft Rejection, Chronic Allograft Nephropathy, Polyomavirus-related Transplant Nephropathy
- Trial name
- RSCS-Campath (NCT01346397)
- Testing
- cyclosporine or tacrolimus
- Where
- Russia
- Volunteers
- 170 people
- Sponsor
- Russian Academy of Medical Sciences
Psychotic Disorders, ADHD
Cognitive Remediation in Forensic Mental Health Care
Forensic patients often display cognitive deficits, particularly in the domain of executive functions, that represent a challenge to forensic rehabilitation.
- Conditions
- Psychotic Disorders, ADHD, TBI (Traumatic Brain Injury), Aggression
- Trial name
- CRFMHC (NCT04610697)
- Testing
- Cognitive Remediation, Active Control
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Neurological and Mental Health Conditions, Genetic Susceptibility
Mapping Antenatal Maternal Stress - Child Outcomes
This study is a sub-study of Mapping Antenatal Maternal Stress (MAMS). Women previously enrolled in MAMS, their children and their partners/spouses were recruited for a set of more comprehensive assessments to characterise early…
- Conditions
- Neurological and Mental Health Conditions, Genetic Susceptibility, Socioeconomic Factors, Psychology, Social
- Trial name
- MAMS-CO (NCT07432243)
- Where
- Singapore
- Volunteers
- 587 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Pain, Rejection
The Role of the Opioid System in Placebo Effects on Pain and Social Rejection
The current study probes the involvement of the opioid system in placebo effects on social pain, using the opioid antagonist naloxone.
- Conditions
- Pain, Rejection, Placebo Effect
- Trial name
- NCT04650841
- Testing
- Control Cream with Naloxone, Control Cream with Saline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
End Stage Liver Disease, Rejection
Study of PD/PK/PG Relationships of Tacrolimus and Cyclosporin in Liver Transplant Patients
To search for suitable pharmacodynamic biomarkers, i.e., with high specificity for calcineurin inhibition and most affected by inter-individual variability, our works aimed at exploring the pharmacodynamics of CNI, the strength…
- Conditions
- End Stage Liver Disease, Rejection, Infection, Malignancy
- Trial name
- 3PIGREF (NCT01760356)
- Where
- Uruguay
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- UDA Centro Nacional Hepato-Bilio-Pancreático
Eating Disorders, Maladaptive Personality Trait
MICBT for Non-underweight Adults With Eating Disorders
Eating disorders (ED) are severe but treatable conditions, but there are large margin for improvements in terms of efficacy and adherence.
- Conditions
- Eating Disorders, Maladaptive Personality Trait, Emotion Regulation, Personality
- Trial name
- MICBT-ED (NCT05503745)
- Testing
- CBT-F+MIT, CBT-E
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Centro Trattamento Integrato: Disturbi Alimentari e Obesita
Breast Cancer, Psychology, Social
Effectiveness of Screening and Brief Interventions for Alcohol and Tobacco During Breast Cancer Treatment (ONKODETOX)
Despite scientific, clinical and political incentives, alcohol and/or tobacco screening and brief intervention (SBI) services are poorly implemented in oncology settings.
- Trial name
- ONKODETOX (NCT03371732)
- Testing
- Motivational Intervention group, Educational advises group
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Institut Bergonié
Organ Transplant Failure or Rejection, Brain Death
Calcineurin Inhibitor in NEuRoloGically Deceased Donors to Decrease Kidney delaYed Graft Function (CINERGY)
The investigators hypothesize that preconditioning neurologically deceased organ donors with the calcineurin inhibitor tacrolimus will improve short and long-term transplant survival without causing harm.
- Conditions
- Organ Transplant Failure or Rejection, Brain Death, Ischemic Reperfusion Injury
- Trial name
- CINERGY (NCT05148715)
- Testing
- Tacrolimus
- Where
- 9 sites in Canada
- Volunteers
- 414 people
- Sponsor
- Université de Sherbrooke
Kidney Transplant Failure and Rejection
Treatment of Early Borderline Lesions in Low Immunological Risk Kidney Transplant Patients (TRAINING)
Background: Subclinical inflammation, including borderline lesions (BL), is very common (30-40%) after kidney transplantation (KT), even in low immunological risk patients, and can lead to interstitial fibrosis/tubular atrophy…
- Trial name
- NCT04936282
- Testing
- Grafalon, Normal Treatment
- Where
- 4 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Fundación Canaria Instituto de Investigación Sanitaria de Canarias
End Stage Renal Disease, Renal Transplant Rejection
MRI in Renal Transplantation
Renal transplantation is the optimal method of treatment for end stage kidney disease however median lifespan of a kidney transplant is around 15 years.
- Conditions
- End Stage Renal Disease, Renal Transplant Rejection, Kidney Transplant Failure and Rejection, Chronic Kidney Diseases
- Trial name
- TransRASL (NCT03705091)
- Testing
- Magnetic resonance imaging
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- NHS Greater Glasgow and Clyde
Behavior, Child, Child Development
Vulnerability/Resilience Factors Influencing the Developmental Trajectories and Adaptive Methods of Children and Adolescents in Child Welfare System.
Assess the prevalence of medico-psychological characteristics at the time of placement (M0), their appearance / disappearance and during the two years following placement (M12 and M24) by age group in children / adolescents in…
- Conditions
- Behavior, Child, Child Development, Child Development Disorder, Adolescent Development
- Trial name
- EvolASE-PEA (NCT05525962)
- Testing
- questionnaries, scales, cognitive tests
- Where
- 5 sites in France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen