Clinical trials: Sodium Bicarbonate
Contrast Induced Nephropathy
Comparison Between Effect of Acetazolamide and NaHco3 in Prevention of Contrast Nephropathy
The purpose of this study is whether Acetazolamide is effective in prevention of contrast nephropathy
- Trial name
- NCT00634491
- Testing
- sodium bicarbonate, Acetazolamide, normal salin
- Where
- Iran
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Liver Cirrhosis
Observational Prospective Study.at the End of the Study the Patients Will be Classified According to PH,Serum Bicarbonate and Serum Sodium Into 6 Groups and Statistical Analysis Will be Performed Using Spss
1-to identify the prognostic value of serum bicarbonate and serum electrolytes at time of admission and their association with development of complications ,length of hospital stay ,prognosis and mortality in hospitalized…
- Trial name
- NCT05082064
- Testing
- arterial blood gases and serum electrolytes
- Where
- Egypt
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Sohag University
Gastric Acid, Human Experimentation
A Pharmacodynamic Study Comparing Zegerid® and Prilosec OTC® (CL2007-17 )(P07813)(COMPLETED)
Open-label randomized crossover design studies. 60 participants will be evaluated on Day 1 to compare effects on stomach acid; 30 participants will continue treatment for 7 days and will have repeat evaluations at Day 7.
- Trial name
- NCT00674115
- Testing
- Omeprazole/sodium bicarbonate, omeprazole magnesium, sodium bicarbonate
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bayer
Pulmonary Ventilation
Impact of NaHCO3- on Exercise Hyperpnea
An abnormally high V̇E/V̇CO2 response to exercise is a key pathophysiological feature of patients with chronic cardiopulmonary disease that is associated with adverse health outcomes.
- Trial name
- NCT03057535
- Testing
- Sodium Bicarbonate, Sodium Chloride
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McGill University
Supplementation, Sport
Acute Sodium Bicarbonate Supplementation in Athletes
The purpose of this study is to verify the effect of acute sodium bicarbonate (SB) and placebo (PLA) supplementation on buffering potential kinetics, physical capacity, discipline-specific performance as well as concentration of…
- Trial name
- NCT03810404
- Testing
- Sodium bicarbonate supplementation
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Gastric Acid, Human Experimentation
A Pharmacodynamic Study Comparing Zegerid® and Prilosec OTC® (Study CL2008-02)(P07814)(COMPLETED)
Open-label randomized crossover design study. 60 participants will be evaluated on Day 1 to compare effects on stomach acid; 30 participants will continue treatment for 7 days and will have repeat evaluations at Day 7.
- Trial name
- NCT00765206
- Testing
- Omeprazole/sodium bicarbonate, omeprazole magnesium (20 mg equivalent)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bayer
Fluid Retention, Fluid Loss
The Effect of AMP Human Sodium Bicarbonate Lotion on Hydration
The purpose of this research study is to evaluate the effects of a topical sodium bicarbonate lotion on physiological and psychological responses associated with hydration status and fluid balance in humans during passive heat…
- Conditions
- Fluid Retention, Fluid Loss, Sodium Retention, Cognitive Change
- Trial name
- AMPlify (NCT04598386)
- Testing
- PR Lotion - AMP Human Performance
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Labour Dystocia
Oral Sodium Bicarbonate for the Prevention of Labour Dystocia
Sodium bicarbonate is often used by athletes to improve their muscle's ability to contract and power their activity. It works by decreasing the risk of lactic acid build-up, which causes cramping and fatigue.
- Trial name
- Labour-Aide (NCT06249061)
- Testing
- oral sodium bicarbonate
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Liz Darling
Chronic Kidney Disease
Pilot Study of Sodium Bicarbonate in Generally Healthy People With Low Bicarbonate
The goal of this pilot study is to determine whether oral sodium bicarbonate can raise low serum bicarbonate concentration in people without chronic kidney disease (CKD).
- Trial name
- NCT02743650
- Testing
- Sodium bicarbonate
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Utah
Supplementation, Sports
Acute Sodium Bicarbonate Supplementation in Female Basketball Players
This randomized, double-blind, placebo-controlled crossover study aims to evaluate the effect of acute sodium bicarbonate supplementation, compared with placebo, on physical capacity and blood biochemical marker concentrations in…
- Trial name
- NCT07730606
- Testing
- Sodium Bicarbonate (NaHCO3)
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Krzysztof Durkalec-Michalski
Local Anesthesia
Effect of Sodium Bicarbonate Buccal Infiltration on the Success of Inferior Alveolar Nerve Block
The purpose of this prospective, randomized, double blind study was to evaluate the effect of a buccal infiltration of sodium bicarbonate on the anesthetic success of the inferior alveolar nerve block (IANB) in patients with…
- Trial name
- NCT02726737
- Testing
- sodium bicarbonate, Lidocaine, sterile distilled water
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Masoud Saatchi
Sodium Bicarbonate, Alkalosis, Metabolic
Effects of Sodium Bicarbonate Supplementation on Intermittent and Intense Task
The aim of this study was to verify if sodium bicarbonate (NaHCO3) suplementation promotes changes in the performance, muscular activity and strength of individuals trained during the intermittent and intense task .
- Conditions
- Sodium Bicarbonate, Alkalosis, Metabolic, Electromyography, Fatigue
- Trial name
- NCT03837886
- Testing
- Sodium bicarbonate, Calcium carbonate
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Nutritional Supplementation, Resistance Training
Caffeine and Sodium Bicarbonate Supplementation Effects on Resistance Training Performance
This research aims to explore the effects of two supplements, caffeine and sodium bicarbonate, on acute (short-term) resistance training performance.
- Trial name
- NCT06714331
- Testing
- Supplements
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Health Adults
Sodium Bicarbonate Solution Enhances Lens Cleanliness in Magnetically Controlled Capsule Endoscopy
Magnetically controlled capsule endoscopy (MCE) is a noninvasive alternative to conventional gastroscopy with comparable diagnostic accuracy.
- Trial name
- NCT07877506
- Testing
- Sodium Bicarbonate Solution
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Local Anesthesia
Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection
This study will test the effectiveness of addition of Sodium Bicarbonate as a buffering agent to the anaesthetic solution on minimizing the pain of injection and increasing the onset time and potency of the anaesthetic solution…
- Trial name
- NCT05473819
- Testing
- Buffered Local Anesthesia, Conventional Unbuffered Local Anesthesia
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Gastroesophageal Reflux Disease
PH Metry Study to Compare the Antacid Activity of Z0063 Versus Gaviscon Double Action Tablets, in Healthy Adult Subjects
Primary Objective: Pharmacodynamics: assessment by pH metry of the change in gastric pH (antacid activity) of Z0063, in comparison to the effect of Gaviscon Double Action Tablets, in healthy adult subjects.
- Trial name
- NCT03069963
- Testing
- Z0063, Gaviscon
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sanofi
Gingivitis, Dental Plaque
Pooled Analysis of Clinical Data From Six GSK Studies to Investigate the Efficacy of a Dentifrice Containing 67% Weight by Weight (w/w) Sodium Bicarbonate on Gingivitis and Plaque Accumulation
The aim of this analysis was to pool data from 6 GSK studies with similar clinical design to investigate the overall efficacy of a test dentifrice containing 67% w/w sodium bicarbonate in the treatment of gingivitis and plaque…
- Trial name
- NCT03703245
- Testing
- Sodium bicarbonate, Control Dentifrice
- Where
- United Kingdom
- Volunteers
- 1,601 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Oral Hygiene
To Evaluate Efficacy and Tolerability of Sodium Bicarbonate Toothpaste and Its Effect on Opportunistic or Resistant Organisms
This study will compare the Gingival Bleeding and Gingival Inflammation following twice daily use of a sodium bicarbonate experimental dentifrice compared to a 0% sodium bicarbonate toothpaste after 24 weeks of use.
- Trial name
- NCT02207400
- Testing
- Sodium bicarbonate and sodium fluoride, Sodium fluoride
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Blood Pressure
Evaluation of the Effect of Sodium Bicarbonate Water on Blood Pressure in Normotensive Subjects
ROX_TENSIO18 is a randomised cross-over trial and the main objective is to evaluate the effect of daily consumption of sodium bicarbonate water for 15 days on blood pressure.
- Trial name
- ROX_TENSIO18 (NCT04282512)
- Testing
- Sodium bicarbonate-rich mineral water
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- My Goodlife SAS
Oral Hygiene
An Efficacy Study of Stain Control of a 67% Sodium Bicarbonate Containing Toothpaste on Chlorhexidine Tooth Staining
The aim of this study is to compare the stain effect on teeth of twice daily brushing with a 67% sodium bicarbonate containing toothpaste versus standard toothpaste (not containing sodium bicarbonate) for six weeks whilst using a…
- Trial name
- NCT01962493
- Testing
- Sodium bicarbonate/ Sodium Fluoride, Sodium fluoride, Chlorhexidine digluconate
- Where
- 3 sites in United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline