Clinical trials: Sodium Disorder
Subarachnoid Hemorrhage, Critical Illness
Crystalloid Fluid Choice and Neurological Outcome in Patients After Subarachnoid Haemorrhage
Patients with subarachnoid hemorrhage are prone to suffer from dysnatriemia. Evidence shows that hyponatriemia is associated with increased incidence of vasospasm, brain swelling and mortality in these patients.
- Conditions
- Subarachnoid Hemorrhage, Critical Illness, Infusion Fluid, Sodium Disorder
- Trial name
- CRYSTALLBrain (NCT04043598)
- Testing
- 0.9% Sodium-chloride, Ringer's Lactate
- Where
- 3 sites in Switzerland
- Volunteers
- 320 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Intraabdominal Infections, Fluid Balance; Disorder
Intra-Abdominal Sepsis and Relationship Between Cumulative Fluid Balance and Serum Sodium and Chloride Levels and In-Hospital Mortality
Intra-abdominal sepsis and septic shock in critically ill surgical patients have a high mortality rate. Fluid therapy is one of the initial resuscitation measures, but it can contribute to poor treatment outcomes through fluid…
- Conditions
- Intraabdominal Infections, Fluid Balance; Disorder, Sodium Disorder, Chloride Disorder
- Trial name
- NCT06838585
- Testing
- infusion therapy
- Where
- Serbia
- Volunteers
- 100 people
- Sponsor
- Clinical Center of Vojvodina
Fluid Retention, Sodium Retention
The Effect of AMP Human Sodium Bicarbonate Lotion on Dehydrated Heat Stress
The primary purpose of the proposed study is to evaluate the effects of a topical sodium bicarbonate lotion (PR Lotion, AMP Human, Park City, UT) on measures of hydration status and fluid balance in humans when exposed to the…
- Conditions
- Fluid Retention, Sodium Retention, Heat Stress, Dehydration (Physiology)
- Trial name
- AMP2 (NCT05092854)
- Testing
- PR Lotion - AMP Human Performance, AminoVital - Rapid Recovery
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Image, Body, Sodium Disorder
Evaluation of Intra Organ Sodium Levels by Magnetic Resonance Imaging
The investigators aim to implement an innovative imaging tool for detection of sodium level changes in-vivo with a clinical magnetic resonance (MR) scanner system.
- Trial name
- NCT05215938
- Testing
- MRI examination
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Heart Failure, Congestive Heart Failure
Alfapump Direct Sodium Removal (DSR) Feasibility Study
First in Human feasibility and sfafety study of the alfapump DSR system in the treatment of Heart failure subects resistant to diuretic therapy.
- Conditions
- Heart Failure, Congestive Heart Failure, Cardiorenal Syndrome, Volume Overload
- Trial name
- RED DESERT (NCT04116034)
- Testing
- alfapump DSR system
- Where
- 2 sites in Belgium, Georgia
- Volunteers
- 8 people
- Sponsor
- Sequana Medical N.V.
Sodium Disorder
Sodium Status in Septic Patients and Its Relation to Prognosis an Hospital Stay
The aim of the present study is to identify the prevalence and prognostic impact of sodium imbalance on sepsis and septic shock patients
- Trial name
- NCT04564508
- Volunteers
- 50 people
- Sponsor
- Assiut University
Thoracic Diseases, Water-Electrolyte Imbalance
TOnicity of Perioperative Maintenance SoluTions
Prospective randomized double blind phase IV trial studying the efficacy and safety of the tonicity of two different perioperative maintenance solutions: an isotonic solution containing NaCl 0.9 in glucose 5% with an added 40…
- Conditions
- Thoracic Diseases, Water-Electrolyte Imbalance, Fluid Overload, Fluid Retention
- Trial name
- TOPMAST-1 (NCT03080831)
- Testing
- NaCl 0.9% in Glucose 5% + 40mmol/L Potassium, Glucion 5%
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Niels Van Regenmortel