Clinical trials: Sodium Intake
Hyperkalemia, Diet Modification
Sodium Zirconium Cyclosilicate to Allow Liberal Fruit and Vegetable Intake for Patients With CKD Stage 3b and 4
Rationale: Several studies have shown that higher urinary potassium excretion (as proxy for potassium intake) is associated with better kidney outcomes, lower blood pressure and improved survival.
- Conditions
- Hyperkalemia, Diet Modification, Chronic Kidney Disease, Sodium Zirconium Cyclosilicate
- Trial name
- LIBRAL (NCT06365684)
- Testing
- Sodium zirconium cyclosilicate
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Leiden University Medical Center
Hypertension in Dialysis Patients, Fluid Overload in Dialysis Patients
Prepared Meals to Prime and Perpetuate Reduced Dietary Sodium Intake in Hemodialysis
This is a randomized clinical trial in which maintenance hemodialysis patients will be provided with salt restricted 'dialysis friendly' meals and compared to a control arm receiving usual care.
- Trial name
- PEPPERDISH (NCT03990311)
- Testing
- Sodium Restricted Meals, Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Tufts Medical Center
Healthy
Effects of Sodium Intake on (PK/PD) Relationship of a Single Dose of a Renin Angiotensin System-Blocker
The impact of sodium intake on plasma drug concentrations has previously been reported in the literature for verapamil and quinidine but, to the investigators' knowledge, never with renin-angiotensin system blockers such as AT1R…
- Trial name
- NCT00310778
- Testing
- high sodium diet, low sodium diet, ramipril 10 mg
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertension
Phosphate in Blood Pressure Regulation
High dietary phosphate intake in the general population is associated with a higher risk for developing kidney disease and cardiovascular disease with an increased overall mortality.
- Trial name
- Phos-RR (NCT02822131)
- Testing
- sodium phosphate, sevelamer, sodium bicarbonate, sodium chloride
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hypertension
Telmisartan and Hydrochlorothiazide Antihypertensive Treatment Study in High Sodium Intake Population
In this research, the investigators aim to compare the antihypertensive efficacy and safety of monotherapy of routine dose angiotensin receptor antagonist telmisartan (ARB) and diuretic Hydrochlorothiazide (HCTZ) in high sodium…
- Trial name
- NCT02255253
- Testing
- Telmisartan, Hydrochlorothiazide
- Where
- 14 sites in China
- Volunteers
- 1,410 people
- Sponsor
- The George Institute for Global Health, China
Sodium Intake, Resistant Hypertension
Therapeutic Effect of Sodium Intake Reduction in Treatment Resistant Hypertension
The aim of this study was to evaluate the therapeutic effect of sodium intake reduction by education in patients with resistant hypertension.
- Trial name
- NCT03424317
- Testing
- Sodium intake reduction, Exercise
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- DongGuk University
Healthy, Hypertrophic Pyloric Stenosis
The Effect of Hypertrophic Pyloric Stenosis (HPS) on Sodium Intake in Childhood
The loss of sodium during infancy causes long term changes in sodium intake. Human research shows that the loss of maternal sodium during pregnancy and neonatal after birth causes an increase sodium intake during childhood.
- Trial name
- NCT01159509
- Testing
- sodium taste tests
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Urinary Sodium Excretion, Salt Intakes
Sodium Sources and Sodium Intake in a Representative Sample of Spanish Children
Previous evidence shows that sodium intake in Spanish adult population is over the recommended limits and this high sodium intake is related with difficulties in body weight control and blood pressure control.
- Conditions
- Urinary Sodium Excretion, Salt Intakes, Body Weight
- Trial name
- NCT03465657
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Universidad Complutense de Madrid
Heart Failure
Estimated Echocardiographic Pulmonary Capillary Wedge Pressure in Heart Failure
The aim of the study was to verify the effects of moderate versus low sodium intake on pulmonary capillary wedge pressure (PCWP), determined by Doppler echocardiography and tissue Doppler imaging in patients suffering from…
- Trial name
- NCT01738659
- Testing
- normal sodium diet
- Volunteers
- 143 people
- Sponsor
- University of Palermo
Orthostatic Hypotension
SalT Supplementation in Older Adults With Orthostatic Intolerance Disorders
Background Orthostatic hypotension (OH) is a common cause of falls, and key source of morbidity and mortality due to injury (e.g. hip fracture).
- Trial name
- STOOD (NCT06188663)
- Testing
- Salt supplementation (encapsulated sodium chloride)
- Where
- Ireland
- Volunteers
- 42 people
- Sponsor
- University of Galway
Hypertension, Overweight or Obesity
Education to Decrease in Sodium Intake Evaluated With 24 Hour Urinary Sodium Excretion (RCT)
WHO identifies as an important risk factor and potentially modifiable to high sodium intake (>2g/day 5g salt/day). Also, an insufficient consumption of potassium ( 3.5 g/day).Therefore, the results of this research could be the…
- Conditions
- Hypertension, Overweight or Obesity, Diabetes Mellitus, Type 2
- Trial name
- RCT (NCT04894344)
- Testing
- Education group
- Where
- Mexico
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Health, Appetite Regulation
Sodium Alginate in Chocolate Milk, Satiety and Glycemic Control
This study compares the effects of isovolumetric (325 ml) preloads of chocolate milk supplemented with sodium alginates at incremental doses on inter-meal glucose levels, appetite scores and food intake in healthy adult men.
- Conditions
- Health, Appetite Regulation, Glucose Metabolism
- Trial name
- NCT01877460
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Sodium Excess, Cardiovascular Risk Factor
A Short, Animated Storytelling Video to Increase Knowledge About Sodium Intake as a Cardiovascular Risk Factor
This study will evaluate the effect of a short, animated storytelling intervention video on sodium intake as a major risk factor for cardiovascular disease on immediate and medium-term retention of knowledge about the risks of…
- Conditions
- Sodium Excess, Cardiovascular Risk Factor, Education Entertainment Intervention, Short, Animated Storytelling
- Trial name
- NCT05735457
- Testing
- A short, animated storytelling video on dietary sodium
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Behavior, Eating
Menu to Meal (M2M) Menu Labeling Intervention Study
This study evaluates the impact of culturally tailored menu labeling interventions on psychosocial factors and ordering behavior among customers in two independently owned Hispanic restaurants in East-Central Texas.
- Trial name
- NCT07329452
- Testing
- Paper menu, Digital menu condition
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Hypertension, Body Weight
Increasing Calcium Dietary Intake Helps to Control Blood Presure and Body Weight
Mediterranean diet is relatively poor in calcium (about 700 mg/daily) whilst there are several reports indicating beneficial effects of calcium-rich diets.
- Trial name
- NCT02295852
- Testing
- LOW-SODIUM LOW LIPID CALCIUM RICH DIET, LOW-SODIUM LOW LIPID DIET
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Federico II University
Hypertension
A Pilot Randomized Controlled Trial to Reduce Salt Intake Among Hypertensive Young Adults in Hong Kong
A pilot randomized controlled trial will be conducted to investigate the feasibility and effectiveness of a salt intake reduction intervention to young hypertension patients in Hong Kong who had high salt intake.
- Trial name
- NCT02920437
- Testing
- Four-week weekly intervention to reduce salt intake, Usual government pamphlets
- Where
- China
- Volunteers
- 19 people
- Sponsor
- The University of Hong Kong
Salty Taste, Spicy Diet
Spicy Diet on Salty Taste and Salt Intake
Excess dietary salt intake is closely associated with the development of hypertension and cardiocerebral vascular diseases. Reduction in high salt intake significantly prevents hypertension and cardiocerebral events.
- Trial name
- NCT01982669
- Testing
- No Intervention
- Where
- China
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- Zhiming Zhu
Hypertension, Hypertension With Abnormal Renal Function
A Pilot Trial of Manlikang in Reducing Salt Intake and Blood Pressure Among Patients With Hypertension
This study is a single arm trial with before-after comparison design. Three groups of patients with hypertension will be recruited: not taking antihypertension drugs and having normal renal function, taking antihypertension drugs…
- Trial name
- NCT03226327
- Testing
- formula salt with very low sodium (Brand name: Manlikang)
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Peking University
Healthy Adult, Alcohol Abstinence
Evaluation of Sodium Excretion and Dietary Intake Via a New Sodium Food Frequency Questionnaire
DETERMINATION OF URINARY SODIUM EXCRETION AND DIETARY SODIUM INTAKE IN ADULTS BY DEVELOPING A FOOD FREQUENCY QUESTIONNAIRE FOR ADDED-SALT FOODS Dear Participant, A doctoral thesis study titled "Determination of Urinary Sodium…
- Conditions
- Healthy Adult, Alcohol Abstinence, Tobacco Abstinence
- Trial name
- NCT07717645
- Testing
- Dietary Assessment (BTS-Salt), Urinary Analysis (Gold Standard vs. Practical), Nutritional Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Toros University
Cardiovascular Risk Factor
The Salty Gut: Effects of High Dietary Salt Intake on the Gut Microbiota
Gut microbiota has a role in cardiovascular disease and recent findings in rodents show dietary salt can negatively alter gut microbiota composition. High salt intake is a risk factor for cardiovascular disease.
- Trial name
- NCT04229680
- Testing
- High Salt, Recommended Salt
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Delaware