Clinical trials: Sodium Lactate
Dietary Supplements, Heart Rate/Drug Effects
Caffeine and Sodium Citrate Ingestion
A positive ergogenic effect of sodium citrate and caffeine ingestion in a short-term, high-intensity exercise task was shown by several studies. These studies were conducted with healthy, able-bodied subjects.
- Conditions
- Dietary Supplements, Heart Rate/Drug Effects, Lactic Acid/Metabolism, Physical Education and Training/Methods
- Trial name
- NCT01591226
- Testing
- Caffeine, Sodium Citrate, Mannitol
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Coronary Heart Disease
Efficacy and Safety of Hypertonic Sodium Lactate Solution Compared With 6% HES Solution in CABG Patients
The choice of fluid therapy is controversial in cardiac surgery. Numerous studies have shown that colloid is better as compared to crystalloids.
- Trial name
- NCT01654653
- Testing
- Hypertonic sodium lactate, 6% Hydroxy Ethyl Starch
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Congenital Heart Disease
Pre Bypass Ultrafiltration (PBUF) in Children Requiring Cardiopulmonary Bypass
Newborn babies and children with congenital heart defects who need heart surgery need to be placed on the heart-lung machine for heart surgery.
- Trial name
- PBUF (NCT03576534)
- Testing
- Use of prebypass ultrafiltration (PBUF)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Boston Children's Hospital
Hepatic Ischemia
Application of Sodium Bicarbonate Ringer's Solution in Laparoscopic Hepatectomy
Compared the effects of Sodium bicarbonate Ringer's solution and lactate Ringer's solution on the internal environment and hemodynamics of patients during laparoscopic liver resection, to observe the application prospect of…
- Trial name
- NCT05830136
- Testing
- sodium bicarbonate Ringer's solution
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Traumatic Brain Injury
Effect of Exogenous Lactate on Neurocognitive in Brain Trauma
Mild traumatic brain injury (TBI) is the most common type of brain injury. Post-mild TBI disability could stem from cognitive, physical, psychological and social dysfunction which resulted in significant disability and…
- Trial name
- NCT01455376
- Testing
- hyperosmolar sodium lactate
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Padjadjaran
Dengue Shock Syndrome
Effect of Hypertonic Sodium Lactate on sVCAM-1 Level as Surrogate Marker of Endothelial Capillary Leakage in Pediatric Dengue Shock Syndrome Patients (DSS)
Dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) are among the leading causes of pediatric hospitalization in Asia.Mortality rates range from 1% at centres experienced in fluid resuscitation, to upto 44% in…
- Trial name
- NCT00966628
- Testing
- Hypertonic sodium lactate, Ringer's lactate
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Hemorrhagic Shock
Efficacy, Safety of Solution Containing Hyperosmolar Sodium Lactate Infusion for Resuscitation of Patients With Hemorrhagic Shock
Indication: Resuscitation in pts with hemorrhagic shock due to multiple injuries Prospective, open label RCT in pts. with traumatic hemorrhagic shock in RS Hasan Sadikin Hospital, Indonesia. PI: Dr.
- Trial name
- NCT01433276
- Testing
- Hyperosmolar sodium lactate, Ringer's lactate
- Where
- Indonesia
- Volunteers
- 71 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Traumatic Brain Injury
Sodium Lactate in Severe TBI
This is a safety phase 2 clinical trial of intravenous infusion of sodium lactate in patients with severe TBI. This study is intended for patients in the acute setting in an intensive care unit at centers that have been selected…
- Trial name
- NCT06701760
- Testing
- Sodium Lactate
- Volunteers
- 264 people
- Sponsor
- University of California, Los Angeles
Severe Sepsis With Septic Shock, Lactate
Using Sodium Lactate Ringer's Injection Resuscitate Septic Shock Patients
Using sodium lactate Ringer's injection resuscitate septic shock patients and Compared with other solution, in order to make clear whether can improve the prognosis.
- Trial name
- NCT02449928
- Testing
- sodium lactate Ringer's injection(Baxter, ShangHai, China), Compound Sodium Chloride Injection (CR Double-Crane, Beijing, China)
- Sponsor
- Peking Union Medical College Hospital
HIV Infections
Effects of Storage on Lactate in Blood Samples
The purpose of this study is to determine whether laboratory storage of samples affects the amount of lactate over 3 years. Lactate is a natural substance normally present in the body.
- Trial name
- NCT00011050
- Where
- 3 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Intra Cerebral Hypertension, Lactate Sodium Solution
Sodium Lactate Versus Hypertonic Saline Solution in the Treatment of Intracranial Hypertensive Episodes in Severe Brain Injured Patients
Brain oedema is a major complication of brain injury (TBI). It increases the risk of intracranial hypertension (ICH) and brain hypoxia, leading to an increase in mortality and poor neurologic outcome.
- Trial name
- SLHYSS (NCT06110429)
- Testing
- Lactate, Sodium, Hypertonic saline
- Volunteers
- 52 people
- Sponsor
- University Hospital, Geneva
Cardiac Arrest, Ischemia Reperfusion Injury
Hypertonic Lactate After Cardiac Arrest
The study is intended to test the hypothesis that sodium lactate infusion after resuscitation from a cardiac arrest will decrease the magnitude of brain damage, as measured by the serum biomarker concentration of NSE.
- Conditions
- Cardiac Arrest, Ischemia Reperfusion Injury, Anoxic Brain Injury
- Trial name
- LATTE (NCT05004610)
- Testing
- Sodium Lactate Solution
- Where
- Belgium
- Volunteers
- 125 people
- Sponsor
- Erasme University Hospital
Septic Shock, Intracranial Hypertension
Study SOLACE SEPSIS
A Pilot, Randomized, Double-Blinded, Controlled Study of Hemodynamic and Acid Base Effects of 0.5M Sodium Lactate and 3% Saline Solutions in Septic Shock Patients
- Trial name
- MJIP1_0 (NCT06634069)
- Testing
- Sodium Lactate, 3% NaCl
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- University Hospital Pilsen
Acute Heart Failure
0.5M Na Lactate Solution in Acute Heart Failure (AHF)
The objective of this trial to see whether: -Cardiac performance (cardiac index and secondary outcomes)can be improved in patients with acute heart failure (AHF) and symptoms and consequences of fluid overload (pulmonary and…
- Trial name
- SOLACE1 (NCT01981655)
- Testing
- 0.5M Sodium lactate, Hartmann's solution
- Where
- Australia
- Volunteers
- 41 people
- Sponsor
- Nepean Blue Mountains Local Health District
Septic Shock
Utility of Sodium Lactate Infusion During Septic Shock
ULIS-1 is an open-label pilot study concerning utility of molar sodium lactate in fluid balance in septic shock patients
- Trial name
- ULIS1 (NCT03528213)
- Testing
- Sodium Lactate light dose, Sodium Lactate high dose, Normal saline
- Where
- 7 sites in France
- Volunteers
- 59 people
- Sponsor
- University Hospital, Lille
Severe Trauma Brain Injury, Intracranial Hypertension
Sodium-Lactate and Traumatic Brain Injury
The purpose of this study is to compare the effect of bolus of either sodium-lactate or mannitol on the evolution of intracranial pressure (ICP) during intracranial hypertensive episodes (IHE)
- Trial name
- NCT00319345
- Testing
- Mannitol, Sodium-Lactate
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Institut d'Anesthesiologie des Alpes Maritimes
Submucosal Tumor of Gastrointestinal Tract
Hydrogel Injection to Assist Endoscopic Submucosal Dissection
The aim of the investigators' study is to evaluate the mucosa-elevating capacity and clinical safety of Sodium Alginate (SA) mixed with Calcium Lactate in assisting Endoscopic Submucosal Dissection/Endoscopic Mucosal Resection.
- Trial name
- NCT03321396
- Testing
- sodium alginate mixed with calcium lactate
- Where
- Taiwan
- Volunteers
- 13 people
- Sponsor
- National Cheng-Kung University Hospital
Acute Kidney Injury
Isotonic Solution Administration Logistical Testing
The administration of intravenous crystalloids is ubiquitous in the care of the critically ill. Commonly available crystalloid solutions contain a broad spectrum of electrolyte compositions including a range of chloride…
- Trial name
- SALT (NCT02345486)
- Testing
- 0.9% sodium chloride, Physiologically balanced fluid
- Where
- United States
- Volunteers
- 974 people
- Sponsor
- Vanderbilt University
Oral Bacterial Infection
Evaluation of the Antibacterial Effect of a Toothpaste Containing Zinc Lactate
The aim of this study is to evaluate the antibacterial effect 12 hours after 4-week use of a toothpaste containing amine base, zinc lactate, and fluoride.
- Trial name
- NCT05628571
- Testing
- Zinc toothpaste, Fluoride Toothpaste
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Subarachnoid Hemorrhage, Aneurysmal
Molar Sodium Lactate Filling in Severe Meningeal Hemorrhage
Subarachnoid hemorrhage by aneurysmal rupture is a serious condition associated with a high mortality rate. Among the complications presented by these patients, vasospasm is one of the main causes of secondary aggravation, in…
- Trial name
- NCT04141371
- Testing
- Molar Sodium Lactate, physiological serum
- Where
- 3 sites in France
- Volunteers
- 3 people
- Sponsor
- Centre Hospitalier Universitaire de Nice