Clinical trials: Soft Tissue
Local Analgesia Via Infiltration, Wound Heal
Comparison of Postoperative Effects of Articaine and Lidocaine in Mucogingival Surgery
The aim of this study is to compare and evaluate the effects of using lidocaine 2% (with adrenaline) and articaine 4% (with adrenaline) in free gingival graft (FGG) surgery on postoperative wound healing, changes in blood flow in…
- Conditions
- Local Analgesia Via Infiltration, Wound Heal, Pain, Postoperative, Hemorrhage
- Trial name
- NCT07145879
- Testing
- Lidocaine hydrochloride 2% with epinephrine 1:100 000, Articaine 4% with epinephrine 1:100,000, Free gingival graft (FGG)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Lymphangioleiomyomatosis, Tuberous Sclerosis Complex
Lymphangioleiomyomatosis, a Study on Cathepsin K
This is a physiopathological case-control, non-interventional, monocentric study of adult patients with lymphangioleiomyomatosis.
- Trial name
- LAM-CAK (NCT05323370)
- Testing
- 24h urine, urine sample
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Hamstring Shortness
Acute Effects of Different Soft Tissue Techniques on Hamstring Tightness
Flexibility is one of the key components of health-related physical fitness and is influenced by various factors such as age, gender, joint structure, and muscle anatomy.
- Trial name
- NCT07260630
- Testing
- Stretching Group, Self-Myofascial Release, Instrument-Assisted Soft Tissue Mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Gazi University
Ankle Injuries
Sural Flap and Anterolateral Thigh Flap in Tissue Reconstruction Around the Ankle
The aim of the study is to evaluate the outcomes of coverage of soft tissue defects of leg and foot by modified sural flap versus anterolateral thigh flap
- Trial name
- NCT04906967
- Testing
- flaps
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sohag University
Muscle Soreness
Investigating the Effects of Different Soft Tissue Mobilizations on Delayed Onset Muscle Soreness
Delayed onset muscle soreness (DOMS) is associated with the initiation of a new physical activity or a sudden increase in exercise volume and intensity.
- Trial name
- NCT04248764
- Testing
- Foam roller application, Massage application
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Wrinkles Such as Nasolabial Folds
Post Market Study of Safety and Performance of RefillHA Volume+ for Facial Soft Tissue Augmentation and Correction of Wrinkles and Folds
This post market study was designed to collect clinical data regarding the safety and performance of RefillHA Volume+ upon its launch, from patients treated with the product in a routine clinical setting of treatments.
- Trial name
- NCT07109635
- Where
- Israel
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Glyance
Healing Surgical Wounds, Pain
L-PRF vs PBM on Extraction Socket Healing
The aim of this study is to compare leukocyte and platelet-rich fibrin (L-PRF) and photobiomodulation (PBM) applications, which have been repeatedly reported to be superior to control groups, in terms of pain, soft tissue and…
- Trial name
- NCT06328413
- Testing
- photobiomodulation, Leukocyte and Platelet Rich Fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Badly Broken Maxillary Premolars Indicated for Extraction, Badly Broken Down Vital Teeth
Soft Tissue Healing After Tooth Extraction
Statement of the problem: Tooth extraction results in hard and soft tissue loss which complicates prosthodontic rehabilitation, So different techniques of alveolar ridge preservation should be done to maintain hard and soft…
- Trial name
- NCT06835543
- Testing
- Amnion membrane., Chorion membrane
- Where
- Egypt
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Uterine Fibroids, Myomas
Laparoscopic Uterine Sparing Techniques Outcomes and Reinterventions
The purpose of this study is to compare the outcomes of two uterine-conserving treatment alternatives for symptomatic uterine fibroids: laparoscopic myomectomy (LM) and global fibroid ablation (GFA) using the Halt System.
- Trial name
- LUSTOR (NCT01750008)
- Testing
- Global Fibroid Ablation, Myomectomy
- Where
- Germany
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Acessa Health, Inc.
Uterine Leiomyoma, Uterine Fibroids
MR Guided Focused Ultrasound Treatment of Uterine Fibroids With Enhanced Sonication
This is a phase 3 study to determine the safety of the new features to the FDA approved ExAblate device using a new method to ablate fibroids deemed Enhanced Sonication.
- Trial name
- NCT00365989
- Testing
- ExAblate Enhanced Sonication
- Where
- 5 sites in United States, Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- InSightec
Uterine Fibroid, Myoma
OCL 500 Treatment of Women With Symptomatic Uterine Fibroids
This is a prospective, open-label, single-arm, safety and effectiveness study of Occlusin 500 microspheres in women with symptomatic uterine fibroids.
- Conditions
- Uterine Fibroid, Myoma, Leiomyoma
- Trial name
- NCT03427671
- Testing
- Occlusin 500 Microspheres
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- IMBiotechnologies Ltd.
Dental Diseases
Soft Tissue Graft Over Immediately Placed Dental Implant in Maxillary Molar Socket
Compare between free tissue graft of buccal pad of fat BFP and free palatal gingival tissue graft for primary soft tissue closure over immediately placed dental implant
- Trial name
- NCT06730191
- Testing
- soft tissue graft covering immediate dental implant
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Mai Ahmed Haggag
Endometriosis, Fibroids
Evaluating Tibolone Add-back in Patients With Endometriosis and Fibroids
While there are many medical options for managing endometriosis and fibroids, GnRH-agonist (GnRH-a) therapy remains a very common method of treating these complex conditions.
- Trial name
- eTAPE (NCT05568940)
- Testing
- Tibolone 2.5 Mg Oral Tablet
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Immediate Implant and Bone Graft
Clinical Evaluation of Soft Tissue Esthetics Around Immediate Implant Using Dual Zone Therapeutic Concept Versus Buccal Gap Fill to Bone Level
Immediate implant placement in the esthetic zone is very challenging procedure although it is documented as a promising procedure (Berglundh, Persson and Klinge, 2002)(Cosyn et al., 2011).
- Trial name
- NCT03768297
- Testing
- dual zone concept
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Disorder of Soft Tissue of Body Wall Region
Investigation of A-ECM for the Correction of Soft Tissue Defects
Soft tissue injury leads to significant deformity in size, shape and body contour. Adipose tissue, continues to be the tissue of choice in repairing soft tissue defects due to traumatic or other defects.
- Trial name
- NCT01992315
- Testing
- Adipose-derived ECM
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aegeria Soft Tissue LLC
Fibroids
Ulipristal vs. GnRHa Prior to Laparoscopic Myomectomy
Rationale: Laparoscopic myomectomy is increasingly performed over laparotomic myomectomy, because of the many benefits for the patient in terms of pain, hospital stay and recovery.
- Trial name
- MYOMEX (NCT02288130)
- Testing
- GnRHa, Ulipristal
- Where
- 9 sites in Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Necrotizing Soft Tissue Infection
Characteristics of Patients With Necrotizing Soft Tissue Infections
To study the demographic characteristic of patients with necrotizing soft tissue infections.
- Trial name
- NCT04801615
- Testing
- Surgery
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Dupuytren's Contracture
Safety and Efficacy of Two Concurrent Injections of AA4500 in Adult Subjects With Multiple Dupuytren's Contractures
The primary objective of this study is to assess the safety of two concurrent injections of AA4500 into the same hand in subjects with multiple Dupuytren's contractures with palpable cords followed 24 to 72 hours later by a…
- Trial name
- NCT01674634
- Testing
- XIAFLEX / XIAPEX
- Where
- 25 sites in United States
- Volunteers
- 715 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Vasodilatation, Oral Soft Tissue Conditions
Endothelium Dependent and Non-dependent Vasodilatation in Human Gingiva
The aim of this study is to compare the endothelim-dependent and non-dependent vasodilatation between genders in the human gingiva.
- Trial name
- NCT04918563
- Testing
- Nitroglycerin, Acetylcholine
- Where
- Hungary
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Edentulous Alveolar Ridge
Zero Echo Time MR for the Assessment of Maxillary Sinus and Dental Regions
The aim of this study is to evaluate the efficacy of zero echo time magnetic resonance imaging (ZTE MRI) as an ionizing radiation-free diagnostic method to evaluate both hard and soft tissues and maxillary sinus region before…
- Trial name
- ZTE-DENTAL (NCT06449443)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University